compositions, methods and uses for cleaning, disinfection and / or sterilization

专利摘要:
This specification discloses a composition that comprises, essentially consists of or consists of available free chlorine or hypochlorous acid and one or more disinfectants, a composition that comprises, essentially consists of or consists of available free chlorine or chlorine acid, one or more disinfectants and a or more surfactants, a composition that comprises, essentially consists of or consists of available free chlorine or hypochlorous acid and one or more surfactants, a composition comprising, essentially consists of or consists of one or more compounds containing guanide and one or more alcohols, kits that comprise, essentially consist of or consist of a disclosed composition, as well as methods and uses for cleaning, disinfecting and / or sterilizing a device using such compositions, methods and uses for cleaning, disinfecting and / or sterilizing a surface area with the use of such compositions, methods and uses to clean, disinfect and / or sterilize a micro infection biana in an individual using such compositions.
公开号:BR112019028093A2
申请号:R112019028093-6
申请日:2018-06-28
公开日:2020-07-28
发明作者:Hojabr Alimi；Sridhar Govinda Prasad；Surya Kanta De
申请人:Collidion, Inc.；
IPC主号:

专利说明:

[0001] [0001] This application claims the priority benefit and filing date, in accordance with 35 USC § 119 (e) of US Provisional Patent Application No. 62 / 526,175, filed on June 28, 2017, and the Patent Application Provisional in US 62 / 577,225, deposited on October 26, 2017, in which the entire content of each of them is incorporated herein by reference in its entirety.
[0002] [0002] In the United States, approximately 46.5 million surgical and even more invasive medical procedures, including approximately 5 million gastrointestinal endoscopies, are performed each year.
[0003] [0003] Endoscopes are used for the diagnosis and treatment of numerous medical conditions and are part of a family of valuable therapeutic and diagnostic tools. Unfortunately, endoscopes have been attributed to more health-related disease outbreaks than any other medical device. This is mainly due to the fact that endoscopes 1) acquire high levels of microbial contamination (biological load) during use due to the types of body cavities to which this device is exposed; and 2) they are fundamentally difficult to clean, disinfect and / or sterilize. For example, in 2012, the source of transmission of “superbug” infections of Carbapenem-resistant Enterobacteriaceae (CRE) in patients in hospitals in Seattle, Pittsburg and Chicago was attributed to contaminated endoscopes.
[0004] [0004] Sterilization of a medical device is preferred since this process destroys or eliminates all forms of microbial life. However, the high temperature and pressures used in sterilization processes are not suitable for heat-sensitive medical devices.
[0005] [0005] This specification describes disinfection compositions, methods and uses that provide superior cleaning and disinfection of a medical device, including a heat-sensitive medical device and a device classified as a critical, semi-critical or non-critical item. At the same time, the disclosed disinfection compositions, methods and uses are less stringent than conventional compositions, methods and uses, resulting in a longer life span of a medical device.
[0006] [0006] Aspects of this specification reveal a composition comprising hypochlorous acid or free available chlorine and one or more disinfectants. A disinfectant disclosed herein may be one or more compounds containing a guanide moiety or functional group, one or more compounds containing aldehyde, or one or more organic peroxides, or any combination thereof.
[0007] [0007] In other respects, this specification discloses a composition comprising hypochlorous acid or free available chlorine, one or more disinfectants and one or more surfactants. A disinfectant disclosed herein may be one or more compounds containing a guanide moiety or functional group, one or more compounds containing aldehyde, or one or more organic peroxides, or any combination thereof. A disclosed guanide-containing compound includes one or more compounds containing biguanide, one or more compounds containing biguanidine, one or more compounds containing triguanide, or any combination thereof. A disclosed aldehyde-containing compound includes one or more aldehydes, one or more dialdehydes, or any combination thereof. A surfactant disclosed in this document can be one or more ionic surfactants, one or more zwitterionic (amphoteric) surfactants or one or more non-ionic surfactants.
[0008] [0008] In other respects, this specification discloses a composition comprising hypochlorous acid or available free chlorine and one or more surfactants. A disinfectant disclosed herein may be one or more compounds containing a guanide moiety or functional group, one or more compounds containing aldehyde, or one or more organic peroxides, or any combination thereof. A disclosed guanide-containing compound includes one or more compounds containing biguanide, one or more compounds containing biguanidine, one or more compounds containing triguanide, or any combination thereof. A disclosed aldehyde-containing compound includes one or more aldehydes, one or more dialdehydes, or any combination thereof. A surfactant disclosed in this document can be one or more ionic surfactants, one or more zwitterionic (amphoteric) surfactants or one or more non-ionic surfactants.
[0009] [0009] In other respects, this specification describes a composition comprising one or more compounds containing guanide and one or more alcohols. A disclosed guanide-containing compound includes one or more compounds containing biguanide, one or more compounds containing biguanidine, one or more compounds containing triguanide, or any combination thereof. A disclosed alcohol includes ethanol, methanol, isopropyl alcohol or any combination thereof.
[0010] [0010] In other respects, this specification describes a method for cleaning, disinfecting and / or sterilizing a device. The method disclosed comprises applying a composition disclosed in this document to a device, wherein applying the clean composition,
[0011] [0011] In other respects, this specification describes a method for cleaning, disinfecting and / or sterilizing a surface area. The disclosed method comprises applying a composition disclosed in this document to a surface area, where applying the composition cleans, disinfects and / or sterilizes the surface area. The method disclosed may further comprise rinsing a clean, disinfected and / or sterilized surface area with a rinse solution disclosed in this document. In other respects, this specification discloses a composition disclosed in this document for use in cleaning, disinfecting and / or sterilizing a surface area. In other respects, this specification discloses a use of a revealed composition that cleans, disinfects and / or sterilizes a surface area.
[0012] [0012] In other respects, this specification describes a method for cleaning, disinfecting and / or sterilizing a microbial infection in an individual. The disclosed method comprises applying a composition disclosed herein to an individual, wherein applying the composition cleans, disinfects and / or sterilizes a microbial infection. In other respects, this specification discloses a composition disclosed in this document for use in cleaning, disinfecting and / or sterilizing a microbial infection in an individual. In other aspects of this specification, the use of a composition revealed to clean, disinfect and / or sterilize a microbial infection in an individual. In other respects, this specification discloses a use of a disclosed composition in the manufacture of a drug to clean, disinfect and / or sterilize a microbial infection in an individual.
[0013] [0013] Disinfection and sterilization are essential to ensure that a medical device does not transmit infectious pathogens to an individual. During manufacture, a medical device for human or veterinary health must be cleaned according to implantable standards before coating and packaging. After use, a medical device must be cleaned, disinfected and / or sterilized to prevent the spread of nosocomial infections (induced by treatment) to a subsequent individual.
[0014] [0014] With regard to cleaning, disinfection and / or sterilization, a medical device can be classified as a critical, semi-critical or non-critical item. A critical item is a device that must be sterile due to the fact that it may be associated with a high risk of infection, since the medical device enters sterile tissue or the vascular system and any microbial contamination can transmit the disease. Non-limiting examples of a medical device that is a critical item include a surgical instrument, a catheter, such as a cardiac or urinary catheter, an implant, a heart-lung machine, and an ultrasound probe used in sterile body cavities .
[0015] [0015] A semi-critical item is a medical device that comes in contact with a mucous membrane or skin that is not intact. Although a medical device must be free of all microorganisms, a small number of bacterial spores are allowed, as the mucous membrane or non-intact skin is generally resistant to infection by common bacterial spores, but susceptible to other organisms, like bacteria, mycobacteria and viruses. As such, a medical device classified as a semi-critical item must undergo minimally high-level disinfection using chemical disinfectants, as this procedure completely eliminates all microorganisms present in the medical device, except for a small number of bacterial spores. Non-limiting examples of a medical device that is a semi-critical item include respiratory therapy equipment, anesthesia equipment, an endoscope, such as a gastrointestinal endoscope, bronchoscope or nasopharyngoscope, arthroscope, laparoscope, blade laryngoscope, esophageal manometry probe, cystoscope, spirometer, anorectal manometry catheter, in vitro fertilization instruments and diaphragm adjustment ring.
[0016] [0016] A non-critical item is a medical device that comes into contact with intact skin, but not with the mucosa. The intact skin acts as an effective barrier for most microorganisms; therefore, the sterility of items that come into contact with intact skin is "non-critical". Virtually no risk has been documented for the transmission of infectious agents to patients through non-critical items when used as non-critical items and do not come into contact with non-intact skin and / or mucous membranes. In contrast to critical and semi-critical items, most non-critical reusable items can be decontaminated where they are used and do not need to be transported to a central processing area. As such, a medical device classified as a non-critical item can be cleaned with a low-level disinfectant. Non-critical items can be divided into a non-critical patient care item and a non-critical environmental surface. Non-limiting examples of a medical device that is a non-critical patient care item include a bedpan, a blood pressure cuff, crutches and a computer. Non-limiting examples of a non-critical environmental surface include a bed rack, a food utensil, a bedside table, furniture and flooring.
[0017] [0017] A composition disclosed in this document is suitable for cleaning, disinfecting and / or sterilizing a medical device. In one aspect of this embodiment, a composition disclosed in the present document is suitable for cleaning, disinfecting and / or sterilizing a heat sensitive medical device. In another aspect of this modality, a composition disclosed in this document is suitable for cleaning, disinfecting and / or sterilizing a medical device classified as a semi-critical or non-critical item.
[0018] [0018] A composition disclosed herein may comprise hypochlorous acid. A weak acid, the chemical formula for hypochlorous acid is HOCl, while its molecular formula is written as HClO. As shown in formula I, hypochlorous acid is a simple molecule with the central oxygen atom connected to the chlorine and hydrogen atoms through simple bonds and has a molar mass of 52.46 g / mol. (I)
[0019] [0019] Hypochlorous acid is a colorless solution and its exact physical properties vary, depending on the concentration of hypochlorous in the solution. Hypochlorous acid reacts with bases to form salts called hypochlorites. For example, sodium hypochlorite (NaOCl), the active ingredient in bleach, is formed by the reaction of hypochlorous acid with sodium hydroxide. Hypochlorous acid also reacts readily with a variety of organic molecules and biomolecules.
[0020] [0020] The hypochlorous acid solution can be produced, for example, by dissolving chlorine in water, by hydrolysis of chlorine gas, electrolysis of a saline solution or acidification of hypochloride. For example, stable hypochlorous salts, such as alkali metal hypochlorites such as sodium hypochlorite, calcium hypochlorite, potassium hypochlorite, lithium hypochlorite and magnesium hypochlorite, can be obtained by dissolving chlorine gas in an aqueous hydroxide solution alkali metal, such as a sodium hydroxide solution, a calcium hydroxide solution, a potassium hydroxide solution, a lithium hydroxide solution, or a magnesium hydroxide solution, respectively. Hypochlorous acid can also be prepared by dissolving dichloride monoxide in water. As another example, hypochlorous acid can also be produced by electrolytic treatment of a saline solution. In one method, an electric current is applied to a three-compartment cell comprising a cathode chamber, an anode chamber and a central saline chamber interposed between the other two chambers, in which each chamber is separated by a semipermeable membrane. . During electrolysis, sodium chloride (NaCl) dissociates into negatively charged chloride (Cl-) and positively charged sodium (Na +).
[0021] [0021] In one embodiment, a composition disclosed in this document comprises an amount of hypochlorous acid that provides a desired beneficial effect to a composition disclosed in this document.
[0022] [0022] In other aspects of this embodiment, a composition disclosed in this document comprises hypochlorous acid in an amount of, for example, about 0.01%, about 0.02%, about 0.025%, about 0.03 %, about 0.04%, about 0.05%, about 0.06%, about 0.07%, about 0.075%, about 0.08%, about 0.09%, about from 0.10%, about 0.11%, about 0.12%, about 0.13%, about 0.14% or about 0.15% by weight of the composition. In still other aspects of this embodiment, a composition disclosed herein comprises hypochlorous acid in an amount of, for example, at least 0.01%, at least 0.02%, at least 0.025%, at least 0.03%, at least 0.04%, at least 0.05%, at least 0.06%, at least 0.07%, at least 0.075%, at least 0.08%, at least 0.09%, at least 0 , 10%, at least 0.11%, at least 0.12%, at least 0.13%, at least 0.14%, or at least 0.15% by weight of the composition.
[0023] [0023] In aspects of this embodiment, a composition disclosed herein comprises hypochlorous acid in an amount of, for example, 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm, 0.30 ppm, 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm, 0.80 ppm, 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm , 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 950 ppm, 1,000 ppm, 1,025 ppm, 1,050 ppm, 1,075 ppm, 1,100 ppm, 1,125 ppm,
[0024] [0024] In still other aspects of this embodiment, a composition disclosed herein comprises hypochlorous acid in an amount of, for example, about 0.5 ppm to about 20 ppm, about 0.5 ppm to about 25 ppm , about 0.5 ppm to about 30 ppm, about 0.5 ppm to about 35 ppm, about 0.5 ppm to about 40 ppm, about 0.5 ppm to about 45 ppm, about from 0.5 ppm to about 50 ppm, about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 60 ppm, about 0 , 5 ppm to about 65 ppm, about 0.5 ppm to about 70 ppm, about 0.5 ppm to about 75 ppm, about 0.5 ppm to about 80 ppm, about 0.5 ppm to about 85 ppm, about 0.5 ppm to about 90 ppm, about 0.5 ppm to about 95 ppm, about 0.5 ppm to about 100 ppm, about 0.75 ppm to about 20 ppm, about 0.75 ppm to about 25 ppm, about 0.75 ppm to about 30 ppm, about 0.75 ppm to about
[0025] [0025] In other aspects of this embodiment, a composition disclosed herein comprises hypochlorous acid in an amount of, for example, about 1 ppm to about 25 ppm, about 1 ppm to about 50 ppm, about 1 ppm at about 75 ppm, about 1 ppm at about 100 ppm, about 1 ppm at about 125 ppm, about 1 ppm at about 150 ppm, about 1 ppm at about 175 ppm, about 1 ppm about 200 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, about 1 ppm to about 250 ppm, about 1 ppm to about 275 ppm, about 1 ppm at about 300 ppm, about 1 ppm at about 325 ppm, about 1 ppm at about 350 ppm, about 1 ppm at about 375 ppm, about 1 ppm at about 400 ppm, about 10 ppm about 25 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, about 10 ppm to about 100 ppm, about 10 ppm at about 125 ppm, about 10 ppm at about 150 ppm, ce about 10 ppm to about 175 ppm, about 10 ppm to about 200 ppm, about 10 ppm to about 225 ppm, about 10 ppm to about 250 ppm, about 10 ppm to about 275 ppm, about 10 ppm to about 275 ppm, about 10 ppm to about 300 ppm, about 10 ppm to about 325 ppm,
[0026] [0026] In other aspects of this embodiment, a composition disclosed herein comprises hypochlorous acid in an amount of, for example, about 400 ppm to about 500 ppm, about 400 ppm to about 600 ppm, about 400 ppm about 700 ppm, about 400 ppm to about 800 ppm, about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 400 ppm to about
[0027] [0027] The concentration of hypochlorous acid in solution can be described as free available chlorine in parts per million. Hypochlorous acid is in equilibrium with hypochlorite ions (OCl-) and dissolved chlorine (Cl2). The extent of equilibrium is determined predominantly by the pH of the solution. Temperature also affects the proportion of the chlorine-free component. Therefore, both FAC and pH need to be known to understand the amount of chlorine present as hypochlorous acid. In general, when the pH range is from about 4.0 to about 5.6, approximately 100% of the available chlorine is present as HOCl. As the pH is reduced below about 4, there is an increase in the dissolved chlorine gas (Cl2). Thus, at a pH of about 3, about 90% of the available chlorine is present as a hypochlorous acid, at a pH of about 2, about 75% of the available chlorine is present as a hypochlorous acid, at a pH of about 1.5, about 50% of the available chlorine is present as hypochlorous acid, while at a pH of about 1, about 25% of the available chlorine is present as hypochlorous acid. As the pH rises above about 5.6, there is an increase in hypochlorite ions (OCl-). Thus, at a pH of a pH of about 6.5, about 90% of the available chlorine is present as hypochlorous acid, at a pH of about 7, about 75% of the available chlorine is present as hypochlorous acid, at at a pH of about 7.5, about 50% of the available chlorine is present as hypochlorous acid, while at a pH of about 8, about 25% of the available chlorine is present as hypochlorous acid.
[0028] [0028] The amount of chlorine can be measured by methods known in the art, like the DPD colorimeter method (Lamotte Company, Chestertown, Maryland) or other known methods established by the Environmental Protection Agency. In the DPD colorimeter method, a yellow color is formed by the reaction of free chlorine with N, N-diethyl-p-phenylenediamine (DPD) and the intensity is measured with a calibrated calorimeter that provides production in parts per million. The additional addition of potassium iodide turns the solution a pink color to provide the total chlorine value.
[0029] [0029] In aspects of this embodiment, a composition disclosed in this document comprises free available chlorine in an amount of, for example, 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm , 0.30 ppm, 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm 0.80 ppm, 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm , 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1,000 ppm, 1,025 ppm, 1,050 ppm , 1,075 ppm, 1,100 ppm, 1,125 ppm, 1,150 ppm, 1,175 ppm, 1,200 ppm, 1,225 ppm,
[0030] [0030] In still other aspects of this embodiment, a composition disclosed in the present document comprises free available chlorine in an amount of, for example, about 0.5 ppm to about 20 ppm, about 0.5 ppm to about 25 ppm, about 0.5 ppm to about 30 ppm, about 0.5 ppm to about 35 ppm, about 0.5 ppm to about 40 ppm, about 0.5 ppm to about 45 ppm, about 0.5 ppm to about 50 ppm, about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 60 ppm, about 0.5 ppm to about 65 ppm, about 0.5 ppm to about 70 ppm, about 0.5 ppm to about 75 ppm, about 0.5 ppm to about 80 ppm, about 0, 5 ppm to about 85 ppm, about 0.5 ppm to about 85 ppm, about 0.5 ppm to about 90 ppm, about 0.5 ppm to about 95 ppm, about 0.5 ppm about 100 ppm, about 0.75 ppm to about 20 ppm, about 0.75 ppm to about 25 ppm, about 0.75 ppm to about 30 ppm, about 0.75 ppm to about 35 ppm, about 0.75 ppm to about 40 ppm, about 0.75 ppm to about 45 ppm, about 0.75 ppm to about 50 ppm, about 0.75 ppm to about 55 ppm, about 0.75 ppm to about 60 ppm, about 0.75 ppm to about 65 ppm, about 0.75 ppm to about 70 ppm, about 0.75 ppm to about 75 ppm, about 0, 75 ppm to about 80 ppm, about 0.75 ppm to about
[0031] [0031] In other aspects of this embodiment, a composition disclosed herein comprises free available chlorine in an amount of, for example, about 1 ppm to about 25 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 75 ppm, about 1 ppm to about 100 ppm, about 1 ppm to about 125 ppm, about 1 ppm to about 150 ppm, about 1 ppm to about 175 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, about 1 ppm to about 250 ppm, about 1 ppm to about 275 ppm, about 1 ppm to about 300 ppm, about 1 ppm to about 325 ppm, about 1 ppm to about 350 ppm, about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, about 10 ppm to about 100 ppm, about 10 ppm to about 125 ppm, about 10 ppm to about 150 ppm, about 10 ppm to about 175 ppm, about 10 ppm to about 200 ppm, about 10 ppm to about 225 ppm, about 10 ppm to about 250 ppm, about 10 ppm to about 275 ppm, about 10 ppm to about 275 ppm, about 10 ppm to about 300 ppm, about 10 ppm to about 325 ppm, about 10 ppm to about 350 ppm, about 10 ppm to about 375 ppm, about 10 ppm to about 400 ppm, about 25 ppm to about 50 ppm, about 25 ppm to about 75 ppm, about
[0032] [0032] In other aspects of this embodiment, a composition disclosed in the present document comprises free available chlorine in an amount of, for example, about 400 ppm to about 500 ppm, about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 400 ppm to about 1,100 ppm, about 400 ppm to about 1,200 ppm, about 400 ppm to about 1,300 ppm, about 400 ppm to about 1,400 ppm, about 400 ppm to about 1,500 ppm, about 500 ppm to about 600 ppm, about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about 500 ppm to about 1,000 ppm, about 500 ppm to 1,100 ppm, about 500 ppm to about 1,200 ppm, about 500 ppm to about 1,300 ppm, about 500 ppm to about 1,400 ppm, about 500 ppm to about
[0033] [0033] In one embodiment, a composition disclosed in this document does not comprise ozone. In another embodiment, a composition disclosed herein may comprise ozone.
[0034] [0034] In one embodiment, a composition disclosed in this document does not comprise hydrogen peroxide. In another embodiment, a composition disclosed herein may comprise hydrogen peroxide.
[0035] [0035] A composition disclosed in this document may comprise a disinfectant. A disinfectant can be one or more compounds containing a portion of biguanide or functional group, one or more compounds containing aldehyde, or one or more organic peroxides, or any combination thereof.
[0036] [0036] A composition disclosed herein may comprise a compound containing a guanid fraction and / or functional group. Non-limiting examples of a compound containing guanide include an organic compound containing a biguanide functional group, a biguanidine functional group or a triguanide functional group. In one embodiment, a guanide-containing compound disclosed herein is a biguanide or a compound containing biguanide. In one aspect of this embodiment, a compound containing biguanide comprises one, two, three, four or five functional groups of biguanide. In one aspect of this modality, a compound containing biguanide comprises formula II,
[0037] [0037] In one embodiment, a compound containing guanide disclosed herein is a biguanidine or a compound containing biguanidine. In one aspect of this embodiment, a compound containing biguanidine comprises one, two, three, four or five functional groups of biguanidine.
[0038] [0038] In one embodiment, a compound containing guanide disclosed herein is a triguanide or a compound containing triguanide. In one aspect of this embodiment, a compound containing triguanide comprises one, two, three, four or five functional groups of triguanide.
[0039] [0039] In one embodiment, a single compound containing guanide is present in a composition disclosed in this document. In another embodiment, a plurality of guanide-containing compounds are present in a composition disclosed herein. In aspects of that embodiment, a composition disclosed herein comprises, for example, one or more compounds containing guanide, two or more compounds containing guanide, three or more compounds containing guanide, four or more compounds containing guanide, four or more compounds containing guanide or five or more guanide containing compounds. In other aspects of this embodiment, a composition disclosed in this document comprises, for example, only one compound containing guanide, a maximum of two compounds containing guanide, a maximum of three compounds containing guanide, a maximum of four compounds containing guanide, or a maximum of five compounds containing guanida. In still other aspects of this embodiment, a composition disclosed herein comprises, for example, 1 to 2 compounds containing guanide, 1 to 3 compounds containing guanide, 1 to 4 compounds containing guanide, 1 to 4 compounds containing guanide, 1 to 5 compounds containing guanide, 2 to 3 compounds containing guanide, 2 to 4 compounds containing guanide, 2 to 5 compounds containing guanide, 3 to 4 compounds containing guanide, 3 to 4 compounds containing guanide, 3 to 5 compounds containing guanide or 4 to 5 compounds containing guanide.
[0040] [0040] Any amount of a compound containing guanide disclosed in this document may be used, provided that the amount is useful for practicing the methods disclosed in this document. In aspects of this embodiment, a composition disclosed herein comprises a compound containing guanide in an amount of, for example, about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about 3.0%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0%, about 10 , 0%. about 11%, about 12%, about 13%, about 14%, about 15%, about 20%, about 25% or about 30% by weight of the composition. In other aspects of this embodiment, a composition disclosed herein comprises a compound containing guanide in an amount of, for example, at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1% , at least 0.25%, at least 0.5%, at least 0.75%, at least 1.0%, at least 1.5%, at least 2.0%, at least 2.5% at least 3.0%, at least 4.0%, at least 5.0%, at least 6.0%, at least 7.0%, at least 7.5%, at least 8.0%, at least 9.0%, at least 10.0%, at least 11%, at least 12%, at least 13%, at least 14%, at least 15%, at least at least 20%, at least 25% or at least 30% by weight of the composition. In still other aspects of this modality, a composition disclosed in the present document comprises a compound containing guanide in an amount of, for example, at most 0.01%, at most 0.05%, at most 0.075%, at most 0.1 %, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0%, maximum 2.5% maximum 3.0%, maximum 4.0%, maximum 4.0%, maximum 5.0%, maximum 6.0%, maximum 7.5%, maximum 8.0%, maximum 9.0%, maximum 10.0%, maximum 11%, maximum 12%, maximum 13%, maximum 14%, maximum 14%, maximum 15%, maximum 20%, maximum 25% or maximum 30% by weight of the composition.
[0041] [0041] In still other aspects of this embodiment, a composition disclosed herein comprises a compound containing guanide in an amount of, for example, about 0.1% to about 0.5%, about 0.1% to about
[0042] [0042] In another embodiment, a composition disclosed herein does not comprise a compound containing guanide. In another embodiment, a composition disclosed in this document does not comprise biguanide. In another embodiment, a composition disclosed herein does not comprise a compound containing biguanide. In another embodiment, a composition disclosed herein does not comprise biguanidine. In another embodiment, a composition disclosed herein does not comprise a compound containing biguanidine. In another embodiment, a composition disclosed in the present document does not comprise triguanide. In another embodiment, a composition disclosed herein does not comprise a compound containing triguanide.
[0043] [0043] A composition disclosed herein may comprise an aldehyde-containing compound. An aldehyde-containing compound can be a linear aldehyde, a branched aldehyde, a cyclic aldehyde, an aromatic aldehyde, a linear dialdehyde, a branched dialdehyde, a cyclic dialdehyde or an aromatic dialdehyde.
[0044] [0044] An aldehyde is an organic compound that contains a functional group −CHO and has a carbonyl center (a carbon with double bond to oxygen) with the carbon atom also attached to hydrogen and an R group. In one embodiment, a aldehyde disclosed herein is a compound of formula V, wherein the group R1 may be H, a C1-6 alkyl, a C1-6 alkane, a C1-6 alkaline, a C3-6 cyclic alkyl or a C3- 6.
[0045] [0045] A dialdehyde is an organic chemical compound with two aldehyde groups. In one embodiment, an aldehyde disclosed herein is a compound of formula VI, wherein group R2 may be a single bond, a C1-6 alkyl, a C1-6 alkane, a C1-6 alkaline, a C3- cyclic alkyl 6 or a C3-6 aryl.
[0046] [0046] In one embodiment, a single compound containing aldehyde is present in a composition disclosed in this document. In another embodiment, a plurality of compounds containing aldehyde is present in a composition disclosed herein. In aspects of this embodiment, a composition disclosed herein comprises, for example, one or more compounds containing aldehyde, two or more compounds containing aldehyde, three or more compounds containing aldehyde, four or more compounds containing aldehyde, four or more compounds containing aldehyde or five or more aldehyde containing compounds. In other aspects of this embodiment, a composition disclosed in this document comprises, for example, only one compound containing aldehyde, at most two compounds containing aldehyde, at most three compounds containing aldehyde, at most four compounds containing aldehyde, at most four compounds containing aldehyde , or at most five compounds containing aldehyde. In yet other aspects of this embodiment, a composition disclosed herein comprises, for example, 1 to 2 compounds containing aldehyde, 1 to 3 compounds containing aldehyde, 1 to 4 compounds containing aldehyde, 1 to 4 compounds containing aldehyde, 1 to 5 compounds containing aldehyde, 2 to 3 compounds containing aldehyde, 2 to 4 compounds containing aldehyde, 2 to 5 compounds containing aldehyde, 3 to 4 compounds containing aldehyde, 3 to 5 compounds containing aldehyde, 3 to 5 compounds containing aldehyde or 4 to 5 compounds containing aldehyde.
[0047] [0047] Any amount of an aldehyde-containing compound disclosed in this document may be used, provided that the amount is useful for practicing the methods disclosed in this document. In aspects of this embodiment, a composition disclosed herein comprises a compound containing aldehyde in an amount of, for example, about 0.01%, about 0.05%, about
[0048] [0048] In still other aspects of this embodiment, a composition disclosed herein comprises a compound containing aldehyde in an amount of, for example, about 0.1% to about 0.5%, about 0.1% to about 0.75%, about 0.1% to about 1.0%, about 0.1% to about 1.5%, about 0.1% to about 2.0%, about from 0.1% to about 2.5%, about 0.2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1.0%, about 0.2% to about 1.5%, about 0.2% to about 2.0%, about 0.2% to about 2.5%, about 0 , 5% to about 1.0%, about 0.5% to about 1.5%, about 0.5% to about 2.0%, about 0.5% to about 2, 5%, about 0.5% to about 3.0%, about 0.5% to about 4.0%, about 0.5% to about 5.0%, about 1.0 % to about 2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0% , about 1.0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%, about 1.0% to fence from 8.0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 2.0% to about 2.5%, about 2.0% to about 3.0%, about 2.0% to about 4.0%, about 2.0% to about 5.
[0049] [0049] In aspects of this embodiment, a composition disclosed herein comprises a compound containing aldehyde in an amount of, for example, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm , 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 975 ppm or 1,000 ppm. In other aspects of this embodiment, a composition disclosed herein comprises an aldehyde-containing compound in an amount of, for example, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm , at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least at least 950 ppm, at least at least 975 ppm or at least 1,000 ppm. In still other aspects of this embodiment, a composition disclosed in this document comprises a compound containing aldehyde in an amount of, for example, a maximum of 100 ppm, a maximum of 125 ppm, a maximum of 150 ppm, a maximum of 175 ppm, a maximum of 175 ppm , maximum 200 ppm, maximum 225 ppm, maximum 250 ppm, maximum 275 ppm, maximum 300 ppm, maximum 325 ppm, maximum 350 ppm, maximum 375 ppm, maximum 375 ppm, maximum 400 ppm , maximum 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm, maximum 550 ppm, maximum 575 ppm, maximum 600 ppm, maximum 625 ppm, maximum 650 ppm , maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, maximum 775 ppm, maximum 800 ppm, maximum 825 ppm, maximum 850 ppm, maximum 875 ppm , maximum 900 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm or maximum 1,000 ppm.
[0050] [0050] In still other aspects of this modality, a composition disclosed in the present document comprises a compound containing aldehyde in an amount of, for example,
[0051] [0051] In another embodiment, a composition disclosed herein does not comprise an aldehyde-containing compound.
[0052] [0052] In one embodiment, a single aldehyde is present in a composition disclosed in this document.
[0053] [0053] Any amount of an aldehyde disclosed in this document can be used, provided that the amount is useful for practicing the methods disclosed in this document. In aspects of this embodiment, a composition disclosed herein comprises an aldehyde in an amount of, for example, about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0 , 9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about 3.0%, about 3.0%, about 4, 0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0% or about 10.0 % by weight of the composition. In other aspects of this embodiment, a composition disclosed herein comprises an aldehyde in an amount of, for example, at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1%, at least at least 0.25%, at least 0.5%, at least 0.75%, at least 1.0%, at least 1.5%, at least 2.0%, at least 2.5%, at least 3.0%, at least 4.0%, at least 5.0%, at least 6.0%, at least 7.0%, at least 7.5%, at least 8.0%, at least 9 , 0% or at least 10.0% by weight of the composition. In still other aspects of this modality, a composition disclosed in this document comprises an aldehyde in an amount of, for example, at most 0.01%, at most 0.05%, at most 0.075%, at most 0.1%, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0%, maximum 2.5% maximum 3.0%, maximum 4.0%, maximum 4.0%, maximum 5.0%, maximum 6.0%, maximum 7.5%, maximum 8.0%, maximum 9.0% or at most 10.0% by weight of the composition.
[0054] [0054] In still other aspects of this modality, a composition disclosed in the present document comprises an aldehyde in an amount of, for example, about 0.1% to about 0.5%, about 0.1% to about 0.75%, about 0.1% to about 1.0%, about 0.1% to about 1.5%, about 0.1% to about 2.0%, about 0 , 1% to about 2.5%, about 0.2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1, 0%, about 0.2% to about 1.5%, about 0.2% to about 2.0%, about 0.2% to about 2.5%, about 0.5 % to about 1.0%, about 0.5% to about 1.5%, about 0.5% to about 2.0%, about 0.5% to about 2.5% , about 0.5% to about 3.0%, about 0.5% to about 4.0%, about 0.5% to about 5.0%, about 1.0% to about 2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0%, about from 1.0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%,
[0055] [0055] In aspects of this embodiment, a composition disclosed herein comprises an aldehyde in an amount of, for example, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm or
[0056] [0056] In still other aspects of this embodiment, a composition disclosed herein comprises an aldehyde in an amount of, for example, about 100 ppm to about 200 ppm, about 100 ppm to about 300 ppm, about 100 ppm to about 400 ppm, about 100 ppm to about 500 ppm, about 100 ppm to about 600 ppm, about 100 ppm to about 700 ppm, about 100 ppm to about 800 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 1,000 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 400 ppm, about 200 ppm to about 500 ppm, about 200 ppm to about 600 ppm, about 200 ppm to about 700 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 900 ppm, about 200 ppm to about 1,000 ppm, about 300 ppm to about 400 ppm, about 300 ppm to about 500 ppm, about 300 ppm to about 600 ppm, about 300 ppm at about 6 00 ppm, about 300 ppm to about 700 ppm, about 300 ppm to about 800 ppm, about 300 ppm to about 900 ppm, about 300 ppm to about 1,000 ppm, about 400 ppm to about 500 ppm, about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about
[0057] [0057] In another embodiment, a composition disclosed in this document does not comprise an aldehyde.
[0058] [0058] In one embodiment, a single dialdehyde is present in a composition disclosed in this document.
[0059] [0059] Any amount of a dialdehyde disclosed in this document can be used, provided that the amount is useful for practicing the methods disclosed in this document. In aspects of this embodiment, a composition disclosed herein comprises a dialdehyde in an amount of, for example, about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0 , 9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about 3.0%, about 3.0%, about 4, 0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0% or about 10.0 % by weight of the composition. In other aspects of this embodiment, a composition disclosed herein comprises a dialdehyde in an amount of, for example, at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1%, at least least 0.25%, at least
[0060] [0060] In still other aspects of this modality, a composition disclosed in the present document comprises a dialdehyde in an amount of, for example, about 0.1% to about 0.5%, about 0.1% to about 0.75%, about 0.1% to about 1.0%, about 0.1% to about 1.5%, about 0.1% to about 2.0%, about 0 , 1% to about 2.5%, about 0.2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1, 0%, about 0.2% to about 1.5%, about 0.2% to about 2.0%, about 0.2% to about 2.5%, about 0.5 % to about 1.0%, about 0.5% to about 1.5%, about 0.5% to about 2.0%, about 0.5% to about 2.5% ,
[0061] [0061] In aspects of this embodiment, a composition disclosed herein comprises a dialdehyde in an amount of, for example, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm or 1,000 ppm. In other aspects of this embodiment, a composition disclosed herein comprises a dialdehyde in an amount of, for example, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm or at least
[0062] [0062] In still other aspects of this embodiment, a composition disclosed herein comprises a dialdehyde in an amount of, for example, about 100 ppm to about 200 ppm, about 100 ppm to about 300 ppm, about 100 ppm to about 400 ppm, about 100 ppm to about 500 ppm, about 100 ppm to about 600 ppm, about 100 ppm to about 700 ppm, about 100 ppm to about 800 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 1,000 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 400 ppm, about 200 ppm to about 500 ppm, about 200 ppm to about 600 ppm, about 200 ppm to about 700 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 900 ppm, about 200 ppm to about 1,000 ppm, about 300 ppm to about 400 ppm, about 300 ppm to about 500 ppm, about 300 ppm to about 600 ppm, about 300 ppm about 600 ppm, about 300 ppm to about 700 ppm, about 300 ppm to about 800 ppm, about 300 ppm to about 900 ppm, about 300 ppm to about 1,000 ppm, about 400 ppm to about 500 ppm, about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 500 ppm to about 600 ppm, about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about 500 ppm to about 1,000 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 1,000 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 800 ppm to about 900 ppm, about 800 ppm to about 1,000 ppm or about 90 0 ppm to about 1,000 ppm.
[0063] [0063] In another embodiment, a composition disclosed in this document does not comprise a dialdehyde.
[0064] [0064] A composition disclosed in this document can comprise an organic peroxide. An organic peroxide is an organic compound containing a functional peroxide group (ROOR '). If one of the R groups is hydrogen, the compound is referred to as an organic hydroperoxide. In one embodiment, an organic peroxide disclosed herein is a compound of formula VII, wherein R 3 and R 4 can each be, independently, H, a C1-6 alkyl, a C1-6 alkane, a C1- alkaline 6, a C3-6 cyclic alkyl or a C3-
[0065] [0065] In one embodiment, a single organic peroxide is present in a composition disclosed in this document. In another embodiment, a plurality of organic peroxides are present in a composition disclosed herein. In aspects of this embodiment, a composition disclosed herein comprises, for example, one or more organic peroxides, two or more organic peroxides, three or more organic peroxides, four or more organic peroxides or five or more organic peroxides. In other aspects of this embodiment, a composition disclosed in this document comprises, for example, only one organic peroxide, a maximum of two organic peroxides, a maximum of three organic peroxides, a maximum of four organic peroxides or a maximum of five organic peroxides. In yet other aspects of this embodiment, a composition disclosed in this document comprises, for example, 1 to 2 organic peroxides, 1 to 3 organic peroxides, 1 to 4 organic peroxides, 1 to 5 organic peroxides, 2 to 3 organic peroxides, 2 to 4 organic peroxides, 2 to 5 organic peroxides, 3 to 4 organic peroxides, 3 to 5 organic peroxides or 4 to 5 organic peroxides.
[0066] [0066] Any amount of organic peroxide disclosed in this document may be used, provided that the amount is useful for practicing the methods disclosed in this document. In aspects of this embodiment, a composition disclosed herein comprises an organic peroxide in an amount of, for example, about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about 3.0%, about 3.0%, about 4 , 0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0% or about 10, 0% by weight of the composition. In other aspects of this embodiment, a composition disclosed herein comprises an organic peroxide in an amount of, for example, at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1%, at least 0.25%,
[0067] [0067] In still other aspects of this modality, a composition disclosed in this document comprises an organic peroxide in an amount of, for example, about 0.1% to about 0.5%, about 0.1% to about 0.75%, about 0.1% to about 1.0%, about 0.1% to about 1.5%, about 0.1% to about 2.0%, about 0.1% to about 2.5%, about 0.2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1 , 0%, about 0.2% to about 1.5%, about 0.2% to about 2.0%, about 0.2% to about 2.5%, about 0, 5% to about 1.0%, about 0.5% to about 1.5%, about 0.5% to about 2.0%, about 0.5% to about 2.5 %, about 0.5% to about 3.0%, about 0.5% to about 4.0%, about 0.5% to about 5.0%, about 1.0% about 2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0%, about 1.0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%, about 1.0% to about 8.0% , about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 2.0% to about 2.5%, about 2.0% to about 3.0%, about 2.0% to about 4.0%, about 2.0% to about 5.0%, about 2.
[0068] [0068] In aspects of this embodiment, a composition disclosed herein comprises an organic peroxide in an amount of, for example, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm,
[0069] [0069] In still other aspects of this embodiment, a composition disclosed herein comprises an organic peroxide in an amount of, for example, about 100 ppm to about 200 ppm, about 100 ppm to about 300 ppm, about 100 ppm to about 400 ppm, about 100 ppm to about 500 ppm, about 100 ppm to about 600 ppm, about 100 ppm to about 700 ppm, about 100 ppm to about 800 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 1,000 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 400 ppm, about 200 ppm to about 500 ppm, about 200 ppm to about 600 ppm, about 200 ppm to about 700 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 900 ppm, about 200 ppm to about 1,000 ppm, about 300 ppm to about 400 ppm, about 300 ppm to about 500 ppm,
[0070] [0070] In another embodiment, a composition disclosed in this document does not comprise an organic peroxide.
[0071] [0071] A composition disclosed in this document can comprise one or more alcohols. An organic peroxide is an organic compound containing a functional peroxide group (ROOR '). If one of the R groups is hydrogen, the compound is referred to as an organic hydroperoxide. In one mode,
[0072] [0072] An alcohol is an organic molecule that comprises a hydroxyl functional group (-OH) attached to a carbon atom, where the carbon atom is saturated.
[0073] [0073] In one embodiment, a single alcohol is present in a composition disclosed in this document.
[0074] [0074] In aspects of this modality, a plurality of alcohols is present in a composition disclosed in the present document can comprise, for example, about 95% of a first alcohol and about 5% of a second alcohol, about 90% of a first alcohol and about 10% of a second alcohol, about 80% of a first alcohol and about 20% of a second alcohol, about 70% of a first alcohol and about 30% of a second alcohol, about 66.7% of a first alcohol and about 33.3% of a second alcohol, about 60% of a first alcohol and about 40% of a second alcohol, about 50% of a first alcohol and about 50% of a second alcohol, about 40% of a first alcohol and about 60% of a second alcohol, about 30% of a first alcohol and about 70% of a second alcohol, about 20% of a first alcohol and about 80% of a second alcohol, about 10% of a first alcohol and about 90% of a second alcohol, about 5% of a first alcohol and about 95 % of a second alcohol. In other aspects of this modality, the ratio between a first alcohol and a second alcohol is, for example, 100: 1, 90: 1, 80: 1, 70: 1, 60: 1, 50: 1, 40: 1, 30 : 1, 20: 1, 19: 1, 18: 1, 17: 1, 16: 1, 15: 1, 14: 1, 13: 1, 12: 1, 11: 1, 10: 1, 9: 1 , 8: 1, 7: 1, 6: 1, 5: 1, 4: 1, 3: 1, 2: 1, 1: 1, 1: 2, 1: 3, 1: 4, 1: 5, 1 : 6, 1: 7, 1: 8, 1: 9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18 , 1:19, 1:20, 1:30, 1:40, 1:50, 1:60, 1:70, 1:80, 1:90 or 1: 100. In other respects, the first alcohol is isopropanol and the second alcohol is ethanol.
[0075] [0075] Any amount of alcohol disclosed in this document may be used, provided that the amount is useful for practicing the methods disclosed in this document. In aspects of this embodiment, a composition disclosed herein comprises an alcohol in an amount of, for example, about 5%, about 10%, about 15%, about 20%, about 25%, about 30 %, about
[0076] [0076] In aspects of this embodiment, a composition disclosed in this document comprises a plurality of alcohols in a total amount of, for example, about 5%, about 10%, about 15%, about 15%, about 20%, about 25%, about 30%, about 35%, about 40%, about 45%, about 50%, about 55%, about 60%, about 65%, about 70%, about 75%, about 80%, about 85%, about 85%, about 95%, about 95%, about 96%, about 97%, about 98%, or about 99% by weight of the composition.
[0077] [0077] In another embodiment, a composition disclosed in this document does not comprise an alcohol. In one aspect of this embodiment, a composition disclosed herein does not comprise ethanol. In another aspect of this embodiment, a composition disclosed herein does not comprise an isopropanol.
[0078] [0078] A composition disclosed in this document may comprise a carrier. A carrier, also known as a vehicle, can be any material typically known in the art of skin care, cosmetic and medical that is used as the basis for formulating a composition disclosed in this document. A carrier can be an aqueous carrier, a semi-solid carrier or a solid carrier. A carrier can also provide a skin care benefit, as revealed in this document.
[0079] [0079] In one embodiment, a single carrier is present in a composition revealed in this document.
[0080] [0080] In another embodiment, a composition disclosed in this document comprises an amount of carrier that provides a desired formulated or beneficial effect to a composition disclosed in this document. In aspects of this embodiment, a composition disclosed in this document comprises a carrier in an amount of, for example, at least 25%, at least 30%, at least 35%, at least 40%, at least 45%, at least 50 %, at least 55%, at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96 %, at least 97%, at least 98% or at least 99% by weight of the composition. In other aspects of this modality, a composition disclosed in this document comprises a carrier in an amount of, for example, a maximum of 25%, a maximum of 30%, a maximum of 35%, a maximum of 40%, a maximum of 45%, a maximum 50%, maximum 55%, maximum 60%, maximum 65%, maximum 70%, maximum 75%, maximum 80%, maximum 85%, maximum 90%, maximum 95%, maximum 96%, maximum 97%, maximum 98% or maximum 99% by weight of the composition. In yet other aspects of this embodiment, a composition disclosed in the present document comprises a carrier in an amount of, for example, about 25% to about 50%, about 25% to about 75%, about 25% to about from 90%, about 25% to about 95%, about 25% to about 96%, about 25% to about 97%, about 25% to about 98%, about 25% to about from 99%, about 50% to about 75%, about 50% to about 90%, about 50% to about 95%, about 50% to about 96%, about 50% to about from 97%, about 50% to about 98%, about 50% to about 99%, about 75% to about 80%, about 75% to about 85%, about 75% to about from 90%, about 75% to about 95%, about 75% to about 96%, about 75% to about 97%, about 75% to about 98%, about 75% to about from 99%, about 80% to about 85%, about 80% to about 90%, about 80% to about 95%, about 80% to about 96%, about 80% to about from 97%, about 80% to about 98%, about 80 % to about 99%, about 85% to about 90%, about 85% to about 95%, about 85% to about 96%, about 85% to about 97%, about 85 % to about 98%, about 85% to about 99%, about 90% to over 95%, about 90% to about 96%, about 90% to about 97%, about 90 % to about 98%, about 90% to about 99%, or about 95% to about 99% by weight of the composition.
[0081] [0081] In another embodiment, a composition disclosed in this document comprises a carrier that is not an alcohol. In aspects of this embodiment, when a composition disclosed in this document comprises hypochlorous acid or free available chlorine, then the composition may comprise a carrier in which the carrier is not an alcohol.
[0082] [0082] A composition disclosed in this document may optionally also include additional ingredients. An additional ingredient is known to be useful in finishing a composition disclosed in this document. An additional ingredient includes, without limitation, a surfactant, a preservative or a chelating agent. An additional ingredient disclosed in the present document is known in the art.
[0083] [0083] Surfactants are compounds that decrease the surface tension of a liquid, allowing easier spreading and decreasing the interfacial tension between two liquids or between a liquid and a solid. When acting on the interface of two surfaces, the surfactants modulate the interfacial tension, resulting in the formation of foam. A single surfactant can be mixed with the buffered solution disclosed in this document, or a plurality of surfactants can be mixed with the buffered solution disclosed in this document. Useful surfactants include, without limitation, ionic surfactants, zwitterionic (amphoteric) surfactants, non-ionic surfactants or any combination thereof. The surfactant used in a composition disclosed herein may vary as appropriate by one skilled in the art and generally depends, in part, on the specific buffer being used, the protein being eluted and the conductivity values employed.
[0084] [0084] Ionic surfactants include anionic surfactants. Anionic surfactants include those based on permanent functional groups attached to the head, such as sulfate, sulfonate, phosphate carboxylates) or pH-dependent anionic surfactants. Anionic surfactants include, without limitation, alkyl sulfates such as ammonium lauryl sulfate and sodium lauryl sulfate (SDS); alkyl ether sulfates such as sodium laureth sulfate and sodium mireth sulfate; docusates like sodium dioctyl sulfosuccinate; sulfonate fluorotensive agents such as perfluorooctane sulfonate (PFOS) and perfluorobutanesulfonate; alkyldiphenyloxide disulfonates such as DOWFAX ™ 2A1 (phenyl-Lauryl-disodium ether disulfonate), DOWFAX ™ 3B2 (phenyl-decyl-disodium ether disulfonate), DOWFAX ™ C10L (phenyl-decyl-disodium ether disulfonate), DO ™ 2EP and ether-phenyl-disodium disulfonate)); potassium phosphate polyether esters such as TRITON ™ H-55 and TRITON ™ H-66; alkylbenzene sulfonates; alkyl aryl phosphates ether; alkyl phosphate ether; alkylcarboxylates as salts of fatty acids and sodium stearate; sodium lauroyl sarcosinate; carboxylate fluorotensive agents such as perfluorononanoate and perfluorooctanoate; and Hexildiphenyl Ether Sulphonate Ether (DOWFAX ™ C6L).
[0085] [0085] Ionic surfactants also include cationic surfactants. Cationic surfactants include those based on permanent or pH-dependent cationic surfactants, such as, for example, primary, secondary or tertiary amines. Cationic surfactants include, without limitation, quaternary ammonium surfactants, such as alkyl trimethylammonium salts and alkyl benzyl dimethylammonium salts, as well as pH-dependent primary, secondary or tertiary amines, as surfactants, in which the primary amines are positively charged in pH greater than 10 or secondary, amines are charged at pH less than 4, such as octenidine dihydrochloride. Non-limiting examples of quaternary ammonium surfactants include first generation quaternary ammonium surfactants comprising C12-18 alkyl chains, second generation quaternary ammonium surfactants which includes aromatic ring groups, third generation quaternary ammonium surfactants comprising compounds of first generation of double quaternary ammonium and / or mixtures of alkyl dimethyl ammonium chloride, fourth generation ammonium surfactants comprising dialkylmethyl amines with twin chains, fifth generation quaternary ammonium surfactants comprising synergistic combinations of double quaternary ammonium compounds, quaternary surfactants sixth generation ammonium compounds comprising polymeric quaternary ammonium compounds and polymeric quaternary ammonium surfactants and seventh generation quaternary surfactants comprising bisquaternary ammonium compounds with polymeric quaternary ammonium compounds.
[0086] [0086] The zwitterionic surfactants are based on primary, secondary or tertiary amines or quaternary ammonium cation with a sulfonate, carboxylate or phosphate. Zwitterionic surfactants include, without limitation, 3 - [(3-colamidopropyl) dimethylammonium] -1- propanesulfonate (CHAPS); sultainas such as cocamidopropyl hydroxysultaine; betaines such as cocamidopropyl betaine; or lecithins.
[0087] [0087] Nonionic surfactants are less denaturing and, as such, are useful for solubilizing membrane proteins and lipids, maintaining protein-protein interactions. Non-ionic surfactants include non-ionic polyether surfactants, non-ionic polyhydroxyl surfactants and biotensoatives. Nonionic surfactants include alcohol ethoxylates, alkylphenol ethoxylates, phenol ethoxylates, amide ethoxylates, glyceride ethoxylates, fatty acid ethoxylates, fatty amine ethoxylates and polyethoxylated tallow amine (POEA). Other useful nonionic surfactants include bio-based nonionic surfactants, including, without limitation, STEPOSOL® MET-10U, a metathesis-derived nonionic surfactant that is a short, unsaturated amide.
[0088] [0088] Non-limiting examples of surfactants include polyoxyethylene glycol sorbitan alkyl esters (or ethoxylated esters of sorbitol) such as sorbitan monooleate polysorbate 20 (TWEEN® 20), sorbitan monooleate polysorbate 40 (TWEEN® 40), sorbitan polysorbate 60 (sorbitan monooleate) TWEEN® 60), polysorbate 61 sorbitan monooleate (TWEEN® 61), polysorbate 65 sorbitan monooleate (TWEEN® 65), polysorbate 80 sorbitan monooleate (TWEEN® 80), polysorbate 81 sorbitan monooleate (TWEEN® 81) and polysorbate 85 monooleate sorbitan (Tween® 85); esters sorbicomo as sorbitan monooleate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate and sorbitan tristearate; polyglycerol esters such as glycerol monooleate, glycerol monolaurate, glycerol monopalmitate, glycerol monostearate, glycerol trioleate, glycerol ricinoleate, glycerol tristearate, glycerol mono and glycerol triacetate; ethoxylated polyglycerol esters; alkyl glucosides such as arachidyl glucoside, C12-20 alkyl glucoside,
[0089] [0089] In one embodiment, a single surfactant is present in a composition disclosed in this document.
[0090] [0090] Any amount of a surfactant disclosed in this document may be used, provided that the amount is useful for practicing the methods disclosed in this document. In aspects of this embodiment, a composition disclosed in this document comprises a surfactant in an amount of, for example, about 0.001%, about 0.005%, about 0.0075%, about 0.01%, about 0, 05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about about 2.5%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0% or about 10.0% by weight of the composition. In other aspects of this embodiment, a composition disclosed herein comprises a surfactant in an amount of, for example, at least 0.001%, at least 0.005%, at least 0.0075%, at least 0.01%, at least
[0091] [0091] In still other aspects of this modality, a composition disclosed in the present document comprises a surfactant in an amount of, for example, about 0.001% to about 0.005%, about 0.001% to about 0.0075%, about from 0.001% to about 0.01%, about 0.001% to about 0.025%, about 0.001% to about 0.05%, about 0.001% to about 0.075%, about 0.001% to about 0.1%, about 0.001% to about 0.25%, about 0.001% to about 0.75%, about 0.001% to about 1.0%, about 0.005% to about
[0092] [0092] In another embodiment, a composition disclosed in this document does not comprise a surfactant.
[0093] [0093] A preservative preserves the stability of a composition disclosed in this document. A preservative can also prevent the growth of microbial organisms in a composition disclosed in this document. Non-limiting examples of a preservative include methyl paraben, phenoxyethanol, capryl glycol, glyceryl caprylate, benzoic acid, sorbic acid, gallic acid and propylparaben.
[0094] [0094] A composition disclosed in this document can be adjusted to any pH that allows a composition disclosed in this document to achieve a desired beneficial effect. In aspects of that embodiment, the pH of a composition disclosed in this document is, for example, at least 2, at least 3, at least 4, at least 5, at least 6, at least 7, at least 8, at least 9 , at least at least 10 or at least 11. In other aspects of this modality, the pH of a composition disclosed in this document is, for example, maximum 2, maximum 3, maximum 4, maximum 5, maximum 6 , maximum 7, maximum 8, maximum 9, maximum 10 or maximum 11.
[0095] [0095] In still other aspects of this modality, the pH of a composition disclosed in the present document is between, for example, about 2 to about 5, about 2 to about 5.5, about 2 to about 6 , about 2 to about
[0096] [0096] In still other aspects of this modality, the pH of a composition disclosed in the present document is between, for example, about 6 to about 8, about 6.7 to about 7.7, about 6.8 to about 7.6, about 6.9 to about 7.6, about 6.9 to about 7.5, about 7.0 to about 7.4, about 7.1 to about of 7.3 or about 7.2.
[0097] [0097] A composition revealed in this document is stable. In one embodiment, a composition disclosed in this document is stable when it shows, for example, a maximum of 1% degradation, a maximum of 2% degradation, a maximum of 3% degradation, a maximum of 4% degradation, a maximum of 5% degradation, maximum 6% degradation, maximum 7%, maximum 8%, maximum 9% or maximum 10% hypochlorous acid. In another embodiment, a composition disclosed in this document is stable when it shows, for example, a maximum of 10% degradation, a maximum of 15% degradation, a maximum of 20% degradation, a maximum of 25% degradation, a maximum of 30% degradation, maximum 35% degradation, maximum
[0098] [0098] In one embodiment, a composition disclosed in this document is stable when it shows, for example, a maximum of 1% degradation, a maximum of 2% degradation, a maximum of 3% degradation, a maximum of 4% degradation, in the maximum 5% degradation, more than 6% degradation, maximum 7% degradation, maximum 8% degradation, maximum 9% degradation or maximum 10% degradation of free chlorine available. In another embodiment, a composition disclosed in this document is stable when it shows, for example, a maximum of 10% degradation, a maximum of 15% degradation, a maximum of 20% degradation, a maximum of 25% degradation, a maximum of 30% degradation, maximum 35% degradation, maximum 40%, maximum 45%, maximum 50%, maximum 55%, maximum 55%, maximum 60%, maximum 65%, maximum 65%, maximum 70% and maximum 75%, maximum 80% degradation, maximum 85% degradation, maximum 90% degradation or maximum 95% degradation of available free chlorine.
[0099] [0099] In aspects of this modality, a composition disclosed in this document is stable for, for example, about 1 day, about 2 days, 3 days, 4 days, 5 days, 6, days, 7 days, 8 days, 9 days, 10 days, 11 days, 12 days, 13 days, 14 days or 15 days. In other aspects of this embodiment, a composition disclosed in this document is stable for, for example, at least 1 day, at least 2 days, at least 3 days, at least 4 days, at least 5 days, at least 6 days, at least 7 days, at least 8 days, at least 9 days, at least 10 days, at least 11 days, at least 12 days, at least 13 days, at least 14 days or at least 15 days. In still other aspects of this modality, a composition revealed in this document is stable for, for example, a maximum of 1 day, a maximum of 2 days, a maximum of 3 days, a maximum of 4 days, a maximum of 5 days, a maximum of 6 days, in maximum 7 days, maximum 8 days, maximum 9 days, maximum 10 days, maximum 11 days, maximum 12 days, maximum 13 days, maximum 14 days or maximum 15 days.
[0100] [0100] In still aspects of this modality, a composition disclosed in this document is stable for, for example, about 1 day to about 2 days, about 1 day to about 3 days, about 1 day to about 4 days, about 1 day to about 5 days, about 1 day to about 6 days, about 1 day to about 7 days, about 1 day to about
[0101] [0101] In other aspects of this embodiment, a composition disclosed in this document is stable for, for example, about 1 week, about 2 weeks, 3 weeks, 4 weeks, 5 weeks, 6, weeks, 7 weeks, 8 weeks , 9 weeks, 10 weeks, 11 weeks, 12 weeks, 13 weeks, 14 weeks or 15 weeks. In still other aspects of this embodiment, a composition disclosed in this document is stable for, for example, at least 1 week, at least 2 weeks, at least 3 weeks, at least 4 weeks, at least 5 weeks, at least 6 weeks, at least 7 weeks, at least 8 weeks, at least 9 weeks, at least 10 weeks, at least 11 weeks, at least 12 weeks, at least 13 weeks, at least 14 weeks or at least 15 weeks. In still other aspects of this modality, a composition disclosed in this document is stable for, for example, a maximum of 1 week, a maximum of 2 weeks, a maximum of 3 weeks, a maximum of 4 weeks, a maximum of 5 weeks, a maximum of 6 weeks, maximum 7 weeks, maximum 8 weeks, maximum 9 weeks, maximum 10 weeks, maximum 11 weeks, maximum 12 weeks, maximum 13 weeks, maximum 14 weeks or maximum 15 weeks.
[0102] [0102] In aspects of this embodiment, a composition disclosed in this document is stable for, for example, about 1 week to about 2 weeks, about 1 week to about 3 weeks, about 1 week to about 4 weeks , about 1 week to about 5 weeks, about 1 week to about 6 weeks, about 1 week to about 7 weeks, about 1 week to about 8 weeks, about 1 week to about 9 weeks , about 1 week to about 10 weeks,
[0103] [0103] In other aspects of this modality, a composition disclosed in this document is stable for, for example, about 1 month, about 2 months, 3 months, 4 months, 5 months, 6, months, 7 months, 8 months , 9 months, 10 months, 11 months, 12 months, 13 months, 14 months, 15 months, 16 months, 17 months or 18 months. In still other aspects of this modality,
[0104] [0104] In aspects of this modality, a composition disclosed in the present document is stable for, for example, about 1 month to about 2 months, about 1 month to about 3 months, about 1 month to about 4 months , about 1 month to about 5 months, about 1 month to about 6 months, about 1 month to about 7 months, about 1 month to about 8 months, about 1 month to about 9 months , about 1 month to about 10 months, about 1 month to about 11 months, about 1 month to about 12 months, about 1 month to about 13 months, about 1 month to about 14 months , about 1 month to about 15 months, about 1 month to about 16 months, about 1 month to about 16 months, about 1 month to about 17 months, about 1 month to about 18 months , about 2 months to about 3 months, about 2 months to about 4 months,
[0105] [0105] In other aspects of this modality, a composition revealed in this document is stable for, for example, about 1 year, about 2 years, about 3 years,
[0106] [0106] A composition disclosed in this document can be formulated in any form that allows the application of a composition disclosed in this document in a manner that achieves a desired beneficial effect. In one embodiment, a composition disclosed in this document can be formulated into, for example, a monophasic formulation or a biphasic formulation comprising a medium phase and a dispersed phase. In another embodiment, a composition disclosed herein can be formulated into, for example, a liquid composition, a colloidal composition, a semi-solid composition or a solid composition. In another embodiment, a composition disclosed herein can be formulated into, for example, a liquid aerosol, foam, emulsion, gel, sol or solid sol. In another embodiment, a composition disclosed in the present document can be formulated in, for example, a sprinkler, a liquid aerosol, a soap or a suspension.
[0107] [0107] In one embodiment, a composition disclosed herein comprises about 80 ppm to about 115 ppm free hypochlorous acid or available chlorine and about 0.01% to about 0.5% of a dialdehyde. In aspects of that embodiment, a composition disclosed herein comprises about 85 ppm to about 110 ppm of free available chlorine or hypochlorous acid and about 0.025% to about 0.4% of a dialdehyde. In other aspects of this embodiment, a composition disclosed herein comprises about 90 ppm to about 105 ppm free hypochlorous acid or chlorine and about 0.05% to about 0.3% of a dialdehyde. In still other aspects of that embodiment, a composition disclosed herein comprises about 95 ppm to about 100 ppm free hypochlorous acid or chlorine and about 0.075% to about 0.2% of a dialdehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 97 ppm of free available chlorine or hypochlorous acid and about 0.1% of a dialdehyde.
[0108] [0108] In one embodiment, a composition disclosed herein comprises about 80 ppm to about 115 ppm free hypochlorous acid or chlorine and about 0.01% to about 0.5% glutaraldehyde. In aspects of that embodiment, a composition disclosed in the present document comprises about 85 ppm to about 110 ppm free hypochlorous acid or chlorine and about 0.025% to about 0.4% glutaraldehyde. In other aspects of that embodiment, a composition disclosed in the present document comprises about 90 ppm to about 105 ppm free hypochlorous acid or chlorine and about 0.05% to about 0.3% glutaraldehyde. In still other aspects of that embodiment, a composition disclosed herein comprises about 95 ppm to about 100 ppm free hypochlorous acid or chlorine and about 0.075% to about 0.2% glutaraldehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 97 ppm of available hypochlorous acid or free chlorine and about 0.1% of glutaraldehyde.
[0109] [0109] In one embodiment, a composition disclosed herein comprises about 80 ppm to about 115 ppm free hypochlorous acid or chlorine and about 0.05% to about 0.6% of a dialdehyde. In aspects of that embodiment, a composition disclosed herein comprises about 85 ppm to about 110 ppm free hypochlorous acid or available chlorine and about 0.075% to about 0.5% of a dialdehyde. In other aspects of this embodiment, a composition disclosed in the present document comprises about 90 ppm to about 105 ppm free hypochlorous acid or chlorine and about 0.1% to about 0.4% of a dialdehyde. In still other aspects of that embodiment, a composition disclosed herein comprises about 95 ppm to about 100 ppm free hypochlorous acid or chlorine and about 0.2% to about 0.3% of a dialdehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 97 ppm of free available chlorine or hypochlorous acid and about 0.25% of a dialdehyde.
[0110] [0110] In one embodiment, a composition disclosed in this document comprises about 80 ppm to about 115 ppm free hypochlorous acid or chlorine and about 0.05% to about 0.6% glutaraldehyde. In aspects of that embodiment, a composition disclosed herein comprises about 85 ppm to about 110 ppm of free available chlorine or hypochlorous acid and about 0.075% to about 0.5% glutaraldehyde. In other aspects of that embodiment, a composition disclosed in the present document comprises about 90 ppm to about 105 ppm free hypochlorous acid or chlorine and about 0.1% to about 0.4% glutaraldehyde. In yet other aspects of that embodiment, a composition disclosed herein comprises about 95 ppm to about 100 ppm free hypochlorous acid or chlorine and about 0.2% to about 0.3% glutaraldehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 97 ppm of available hypochlorous acid or free chlorine and about 0.25% glutaraldehyde.
[0111] [0111] In one embodiment, a composition disclosed herein comprises about 80 ppm to about 115 ppm free hypochlorous acid or chlorine and about 0.1% to about 1.0% of a dialdehyde. In aspects of that embodiment, a composition disclosed herein comprises about 85 ppm to about 110 ppm free hypochlorous acid or chlorine and about 0.2% to about 0.8% of a dialdehyde. In other aspects of this embodiment, a composition disclosed in the present document comprises about 90 ppm to about 105 ppm available hypochlorous acid or free chlorine and about 0.3% to about 0.7% of a dialdehyde. In yet other aspects of that embodiment, a composition disclosed herein comprises about 95 ppm to about 100 ppm free hypochlorous acid or chlorine and about 0.4% to about 0.6% of a dialdehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 97 ppm of available free chlorine or hypochlorous acid and about 0.5% of a dialdehyde.
[0112] [0112] In one embodiment, a composition disclosed in this document comprises about 80 ppm to about 115 ppm free hypochlorous acid or chlorine and about 0.1% to about 1.0% glutaraldehyde. In aspects of that embodiment, a composition disclosed in the present document comprises about 85 ppm to about 110 ppm free hypochlorous acid or chlorine and about 0.2% to about 0.8% glutaraldehyde. In other aspects of this embodiment, a composition disclosed in the present document comprises about 90 ppm to about 105 ppm free hypochlorous acid or chlorine and about 0.3% to about 0.7% glutaraldehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 95 ppm to about 100 ppm free hypochlorous acid or chlorine and about 0.4% to about 0.6% glutaraldehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 97 ppm of available hypochlorous acid or free chlorine and about 0.5% glutaraldehyde.
[0113] [0113] In one embodiment, a composition disclosed in the present document comprises about 4% to about 12% of the compound containing biguanide, about 60% to about 80% of an alcohol and about 0.1% to about 5.0% of a dialdehyde.
[0114] [0114] In one embodiment, a composition disclosed herein comprises about 4% to about 12% polyhexamethylene biguanide, about 60% to about 80% isopropanol and about 0.1% to about 5.0% glutaraldehyde.
[0115] [0115] In one embodiment, a composition disclosed herein comprises about 5% to about 15% of the compound containing biguanide, about 60% to about 80% of an alcohol and about 0.1% to about 1.0% of a dialdehyde.
[0116] [0116] In one embodiment, a composition disclosed herein comprises about 5% to about 15% polyhexamethylene biguanide, about 60% to about 80% isopropanol and about 0.1% to about 1.0% ortho-phthalaldehyde. In aspects of that embodiment, a composition disclosed in the present document comprises about 6.5% to about 12.5% polyhexamethylene biguanide, about 62% to about 78% isopropanol and about 0.2% to about 0.8% ortho-phthalaldehyde. In other aspects of this embodiment, a composition disclosed in this document comprises about 7.5% to about 11.5% polyhexamethylene biguanide, about 65% to about 75% isopropanol and about 0.3% to about 0.7% ortho-phthalaldehyde. In still other aspects of this embodiment, a composition disclosed herein comprises about 8.5% to about 10.5% polyhexamethylene biguanide, about 67% to about 73% isopropanol and about 0.4 %
[0117] [0117] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide, about 60% to about 80% of an alcohol and about 1% to about 10% of a quaternary ammonium surfactant. In aspects of this embodiment, a composition disclosed in this document comprises about 2% to about 8% of compound containing biguanide, about 62% to about 78% of an alcohol and about 2% to about 8% of an quaternary ammonium surfactant. In other aspects of this embodiment, a composition disclosed in this document comprises about 3% to about 7% of the compound containing biguanide, about 65% to about 75% of an alcohol and about 3% to about 7% of a quaternary ammonium surfactant. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 4% to about 6% of compound containing biguanide, about 67% to about 73% of an alcohol and about 4% to about 6% of a quaternary ammonium surfactant. In still other aspects of this modality, a composition disclosed in the present document comprises about 5% of compound containing biguanide, about 70% of an alcohol and about 5% of a quaternary ammonium surfactant.
[0118] [0118] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide, about 60% to about 80% isopropanol and about 1% to about 10% of benzalkonium chloride. In aspects of that embodiment, a composition disclosed herein comprises about 2% to about 8% polyhexamethylene biguanide, about 62% to about 78% isopropanol and about 2% to about 8% chloride benzalkonium. In other aspects of this embodiment, a composition disclosed in the present document comprises about 3% to about 7% of polyhexamethylene biguanide, about 65% to about 75% of isopropanol and about 3% to about 7% of benzalkonium chloride. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 4% to about 6% of polyhexamethylene biguanide, about 67% to about 73% isopropanol and about 4% to about 6% of benzalkonium chloride. In yet other aspects of this embodiment, a composition disclosed herein comprises about 5% polyhexamethylene biguanide, about 70% isopropanol and about 5% benzalkonium chloride.
[0119] [0119] In one embodiment, a composition disclosed herein comprises about 5% to about 15% of the compound containing biguanide, about 55% to about 75% of an alcohol and about 1% to about 10% of a quaternary ammonium surfactant. In aspects of this embodiment, a composition disclosed in this document comprises about 7% to about 13% of compound containing biguanide, about 57% to about 73% of an alcohol and about 2% to about 8% of an quaternary ammonium surfactant. In other aspects of that embodiment, a composition disclosed in the present document comprises about 8% to about 12% of the compound containing biguanide, about 60% to about 70% of an alcohol and about 3% to about 7% of a quaternary ammonium surfactant. In yet other aspects of this embodiment, a composition disclosed in the present document comprises about 9% to about 11% of the compound containing biguanide, about 62% to about 68% of an alcohol and about 4% to about 6% of a quaternary ammonium surfactant. In still other aspects of this modality, a composition disclosed in the present document comprises about 10% of compound containing biguanide, about 65% of an alcohol and about 5% of a quaternary ammonium surfactant.
[0120] [0120] In one embodiment, a composition disclosed herein comprises about 5% to about 15% polyhexamethylene biguanide, about 55% to about 75% isopropanol and about 1% to about 10% of benzalkonium chloride. In aspects of this embodiment, a composition disclosed in this document comprises about 7% to about 13% polyhexamethylene biguanide, about 57% to about 73% isopropanol and about 2% to about 8% chloride benzalkonium. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% of polyhexamethylene biguanide, about 60% to about 70% of isopropanol and about 3% to about 7% of benzalkonium chloride. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to 11% polyhexamethylene biguanide, about 62% to about 68% isopropanol and about 4% to about 6% chloride benzalkonium. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 10% polyhexamethylene biguanide, about 65% isopropanol and about 5% benzalkonium chloride.
[0121] [0121] In one embodiment, a composition disclosed herein comprises about 85 ppm to about 120 ppm free hypochlorous acid or chlorine and about 1.0% to about 3.0% biguanide-containing compound. In aspects of that embodiment, a composition disclosed herein comprises about 90 ppm to about 115 ppm free hypochlorous acid or chlorine and about 1.25% to about 2.75% biguanide-containing compound. In other aspects of that embodiment, a composition disclosed herein comprises about 95 ppm to about 110 ppm free hypochlorous acid or chlorine and about 1.5% to about 2.5% of the compound containing biguanide. In still other aspects of that embodiment, a composition disclosed herein comprises about 100 ppm to about 106 ppm available hypochlorous acid or free chlorine and about 1.75% to about 2.25% biguanide-containing compound. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 103 ppm of available hypochlorous acid or free chlorine and about 2.0% of compound containing biguanide.
[0122] [0122] In one embodiment, a composition disclosed herein comprises about 85 ppm to about 120 ppm free hypochlorous acid or available chlorine and about 1.0% to about 3.0% polyhexamethylene biguanide. In aspects of that embodiment, a composition disclosed herein comprises about 90 ppm to about 115 ppm free hypochlorous acid or chlorine and about 1.25% to about 2.75% polyhexamethylene biguanide. In other aspects of this embodiment, a composition disclosed in the present document comprises about 95 ppm to about 110 ppm free hypochlorous acid or chlorine and about 1.5% to about 2.5% polyhexamethylene biguanide. In yet other aspects of that embodiment, a composition disclosed herein comprises about 100 ppm to about 106 ppm free hypochlorous acid or chlorine and about 1.75% to about 2.25% polyhexamethylene biguanide. In still other aspects of this embodiment, a composition disclosed herein comprises about 103 ppm of available free chlorine or hypochlorous acid and about 2.0% of polyhexamethylene biguanide.
[0123] [0123] In one embodiment, a composition disclosed herein comprises about 85 ppm to about 120 ppm free hypochlorous acid or available chlorine and about 0.5% to about 2.5% of the compound containing biguanide. In aspects of that embodiment, a composition disclosed herein comprises about 90 ppm to about 115 ppm free hypochlorous acid or chlorine and about 0.75% to about 2.25% biguanide-containing compound. In other aspects of this embodiment, a composition disclosed in the present document comprises about 95 ppm to about 110 ppm free hypochlorous acid or chlorine and about 1.0% to about 2.0% biguanide-containing compound. In still other aspects of that embodiment, a composition disclosed herein comprises about 100 ppm to about 106 ppm free hypochlorous acid or chlorine and about 1.25% to about 1.75% biguanide-containing compound. In yet other aspects of this embodiment, a composition disclosed herein comprises about 103 ppm of free available chlorine or hypochlorous acid and about 1.5% of compound containing biguanide.
[0124] [0124] In one embodiment, a composition disclosed herein comprises about 85 ppm to about 120 ppm free hypochlorous acid or chlorine and about 0.5% to about 2.5% polyhexamethylene biguanide. In aspects of that embodiment, a composition disclosed herein comprises about 90 ppm to about 115 ppm free hypochlorous acid or chlorine and about 0.75% to about 2.25% polyhexamethylene biguanide. In other aspects of this embodiment, a composition disclosed herein comprises about 95 ppm to about 110 ppm free hypochlorous acid or chlorine and about 1.0% to about 2.0% polyhexamethylene biguanide. In still other aspects of this embodiment, a composition disclosed herein comprises about 100 ppm to about 106 ppm free hypochlorous acid or chlorine and about 1.25% to about 1.75% polyhexamethylene biguanide. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 103 ppm of available hypochlorous acid or free chlorine and about 1.5% of polyhexamethylene biguanide.
[0125] [0125] In one embodiment, a composition disclosed herein comprises about 0.1% to about 7% of the compound containing biguanide and about 60% to about 80% of one or more alcohols. In aspects of that embodiment, a composition disclosed in the present document comprises about 0.5% to about 6% of compound containing biguanide and about 62% to about 78% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 1% to about 5% of compound containing biguanide and about 65% to about 75% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 2% to about 4% of compound containing biguanide and about 67% to about 73% of one or more alcohols.
[0126] [0126] In one embodiment, a composition disclosed herein comprises about 0.1% to about 7% polyhexamethylene biguanide and about 60% to about 80% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 0.5% to about 6% of polyhexamethylene biguanide and about 62% to about 78% of isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 1% to about 5% of polyhexamethylene biguanide and about 65% to about 75% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 2% to about 4% polyhexamethylene biguanide and about 67% to about 73% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 3% polyhexamethylene biguanide and about 70% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0127] [0127] In one embodiment, a composition disclosed herein comprises about 0.1% to about 7% of the compound containing biguanide and about 50% to about 70% of one or more alcohols. In aspects of that embodiment, a composition disclosed in the present document comprises about 0.5% to about 6% of compound containing biguanide and about 52% to about 68% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 1% to about 5% of compound containing biguanide and about 55% to about 65% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 2% to about 4% of compound containing biguanide and about 57% to about 63% of one or more alcohols.
[0128] [0128] In one embodiment, a composition disclosed herein comprises about 0.1% to about 7% polyhexamethylene biguanide and about 50% to about 70% isopropanol. In aspects of this embodiment, a composition disclosed in the present document comprises about 0.5% to about 6% polyhexamethylene biguanide and about 52% to about 68% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 1% to about 5% of polyhexamethylene biguanide and about 55% to about 65% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 2% to about 4% polyhexamethylene biguanide and about 57% to about 63% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 3% polyhexamethylene biguanide and about 60% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0129] [0129] In one embodiment, a composition disclosed herein comprises about 0.1% to about 7% of the compound containing biguanide and about 40% to about 60% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 0.5% to about 6% of compound containing biguanide and about 42% to about 58% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 1% to about 5% of compound containing biguanide and about 45% to about 55% of one or more alcohols. In still other aspects of that embodiment, a composition disclosed herein comprises about 2% to about 4% of compound containing biguanide and about 47% to about 53% of one or more alcohols.
[0130] [0130] In one embodiment, a composition disclosed herein comprises about 0.1% to about 7% polyhexamethylene biguanide and about 40% to about 60% isopropanol. In aspects of this embodiment, a composition disclosed herein comprises about 0.5% to about 6% polyhexamethylene biguanide and about 42% to about 58% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 1% to about 5% of polyhexamethylene biguanide and about 45% to about 55% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 2% to about 4% polyhexamethylene biguanide and about 47% to about 53% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 3% polyhexamethylene biguanide and about 50% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0131] [0131] In one embodiment, a composition disclosed herein comprises about 1% to about 15% of the compound containing biguanide and about 20% to about 85% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 25% to about 80% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 12% of the compound containing biguanide and about 30% to about 75% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 35% to about 70% of one or more alcohols.
[0132] [0132] In one embodiment, a composition disclosed herein comprises about 1% to about 15% polyhexamethylene biguanide and about 20% to about 85% isopropanol. In aspects of that embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 25% to about 80% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 4% to about 12% polyhexamethylene biguanide and about 30% to about 75% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 11% polyhexamethylene biguanide and about 35% to about 70% isopropanol. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 6% to about 10% of polyhexamethylene biguanide and about 40% to about 60% of isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0133] [0133] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide and about 60% to about 80% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 3% to about 9% of the compound containing biguanide and about 62% to about 78% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% of the compound containing biguanide and about 65% to about 75% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 67% to about 73% of one or more alcohols.
[0134] [0134] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide and about 60% to about 80% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 3% to about 9% polyhexamethylene biguanide and about 62% to about 78% isopropanol. In other aspects of that embodiment, a composition disclosed herein comprises about 4% to about 8% polyhexamethylene biguanide and about 65% to about 75% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% polyhexamethylene biguanide and about 67% to about 73% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 6% polyhexamethylene biguanide and about 70% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0135] [0135] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide and about 55% to about 75% of one or more alcohols. In aspects of that embodiment, a composition disclosed in the present document comprises about 3% to about 9% of the compound containing biguanide and about 57% to about 73% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% of compound containing biguanide and about 60% to about 70% of one or more alcohols. In still other aspects of that embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 62% to about 68% of one or more alcohols.
[0136] [0136] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide and about 55% to about 75% isopropanol. In aspects of such an embodiment, a composition disclosed in the present document comprises about 3% to about 9% polyhexamethylene biguanide and about 57% to about 73% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% polyhexamethylene biguanide and about 60% to about 70% isopropanol. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 5% to about 7% of polyhexamethylene biguanide and about 62% to about 68% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 6% polyhexamethylene biguanide and about 65% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0137] [0137] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide and about 50% to about 70% of one or more alcohols. In aspects of that embodiment, a composition disclosed in the present document comprises about 3% to about 9% of the compound containing biguanide and about 52% to about 68% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% of compound containing biguanide and about 55% to about 65% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 57% to about 63% of one or more alcohols.
[0138] [0138] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide and about 50% to about 70% isopropanol. In aspects of that embodiment, a composition disclosed herein comprises about 3% to about 9% polyhexamethylene biguanide and about 52% to about 68% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% polyhexamethylene biguanide and about 55% to about 65% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% polyhexamethylene biguanide and about 57% to about 63% isopropanol. In yet other aspects of this embodiment, a composition disclosed herein comprises about 6% polyhexamethylene biguanide and about 60% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0139] [0139] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide and about 45% to about 65% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 3% to about 9% of the compound containing biguanide and about 47% to about 63% of one or more alcohols. In other aspects of this embodiment, a composition disclosed in the present document comprises about 4% to about 8% of compound containing biguanide and about 50% to about 60% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 52% to about 58% of one or more alcohols.
[0140] [0140] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide and about 45% to about 65% isopropanol. In aspects of this embodiment, a composition disclosed herein comprises about 3% to about 9% polyhexamethylene biguanide and about 47% to about 63% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% polyhexamethylene biguanide and about 50% to about 60% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% polyhexamethylene biguanide and about 52% to about 58% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 6% polyhexamethylene biguanide and about 55% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0141] [0141] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide and about 40% to about 60% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 3% to about 9% of the compound containing biguanide and about 42% to about 58% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% of the compound containing biguanide and about 45% to about 55% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 47% to about 53% of one or more alcohols.
[0142] [0142] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide and about 40% to about 60% isopropanol. In aspects of this embodiment, a composition disclosed herein comprises about 3% to about 9% polyhexamethylene biguanide and about 42% to about 58% isopropanol. In other aspects of that embodiment, a composition disclosed herein comprises about 4% to about 8% polyhexamethylene biguanide and about 45% to about 55% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% polyhexamethylene biguanide and about 47% to about 53% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 6% polyhexamethylene biguanide and about 50% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0143] [0143] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide and about 35% to about 55% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 3% to about 9% of the compound containing biguanide and about 37% to about 53% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% of compound containing biguanide and about 40% to about 50% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 42% to about 48% of one or more alcohols.
[0144] [0144] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide and about 35% to about 55% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 3% to about 9% polyhexamethylene biguanide and about 37% to about 53% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% polyhexamethylene biguanide and about 40% to about 50% isopropanol. In still other aspects of that embodiment, a composition disclosed in the present document comprises about 5% to about 7% of polyhexamethylene biguanide and about 42% to about 48% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 6% polyhexamethylene biguanide and about 45% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0145] [0145] In one embodiment, a composition disclosed in this document comprises about 1% to about 10% of the compound containing biguanide and about 30% to about 50% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 3% to about 9% of the compound containing biguanide and about 32% to about 48% of one or more alcohols. In other aspects of this embodiment, a composition disclosed in the present document comprises about 4% to about 8% of compound containing biguanide and about 35% to about 45% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 37% to about 43% of one or more alcohols.
[0146] [0146] In one embodiment, a composition disclosed in this document comprises about 1% to about 10% polyhexamethylene biguanide and about 30% to about 50% isopropanol.
[0147] [0147] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide and about 25% to about 45% of one or more alcohols. In aspects of that embodiment, a composition disclosed in the present document comprises about 3% to about 9% of the compound containing biguanide and about 27% to about 43% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% of the compound containing biguanide and about 30% to about 40% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide and about 32% to about 38% of one or more alcohols.
[0148] [0148] In one embodiment, a composition disclosed herein comprises about 1% to about 10% polyhexamethylene biguanide and about 25% to about 45% isopropanol. In aspects of that embodiment, a composition disclosed herein comprises about 3% to about 9% polyhexamethylene biguanide and about 27% to about 43% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% polyhexamethylene biguanide and about 30% to about 40% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% polyhexamethylene biguanide and about 32% to about 38% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 6% polyhexamethylene biguanide and about 35% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0149] [0149] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 60% to about 80% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 62% to about 78% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 65% to about 75% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 67% to about 73% of one or more alcohols.
[0150] [0150] In one embodiment, a composition disclosed in this document comprises about 3% to about 13% polyhexamethylene biguanide and about 60% to about 80% isopropanol. In aspects of this embodiment, a composition disclosed herein comprises about 5% to about 11% polyhexamethylene biguanide and about 62% to about 78% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% polyhexamethylene biguanide and about 65% to about 75% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% polyhexamethylene biguanide and about 67% to about 73% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 8% polyhexamethylene biguanide and about 70% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0151] [0151] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 55% to about 75% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 57% to about 73% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 60% to about 70% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 62% to about 68% of one or more alcohols.
[0152] [0152] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 55% to about 75% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 5% to about 11% polyhexamethylene biguanide and about 57% to about 73% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 6% to about 10% polyhexamethylene biguanide and about 60% to about 70% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% polyhexamethylene biguanide and about 62% to about 68% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 8% polyhexamethylene biguanide and about 65% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0153] [0153] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 50% to about 70% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 52% to about 68% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 55% to about 65% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 57% to about 63% of one or more alcohols.
[0154] [0154] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 50% to about 70% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 5% to about 11% polyhexamethylene biguanide and about 52% to about 68% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% polyhexamethylene biguanide and about 55% to about 65% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% polyhexamethylene biguanide and about 57% to about 63% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 8% polyhexamethylene biguanide and about 60% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0155] [0155] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 45% to about 65% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 47% to about 63% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 50% to about 60% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 52% to about 58% of one or more alcohols.
[0156] [0156] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 45% to about 65% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 5% to about 11% polyhexamethylene biguanide and about 47% to about 63% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% polyhexamethylene biguanide and about 50% to about 60% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% polyhexamethylene biguanide and about 52% to about 58% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 8% polyhexamethylene biguanide and about 55% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0157] [0157] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 40% to about 60% of one or more alcohols. In aspects of that embodiment, a composition disclosed in the present document comprises about 5% to about 11% of the compound containing biguanide and about 42% to about 58% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 45% to about 55% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 47% to about 53% of one or more alcohols.
[0158] [0158] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 40% to about 60% isopropanol. In aspects of this embodiment, a composition disclosed in the present document comprises about 5% to about 11% polyhexamethylene biguanide and about 42% to about 58% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 6% to about 10% of polyhexamethylene biguanide and about 45% to about 55% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% polyhexamethylene biguanide and about 47% to about 53% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 8% polyhexamethylene biguanide and about 50% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0159] [0159] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 35% to about 55% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 37% to about 53% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 40% to about 50% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 42% to about 48% of one or more alcohols.
[0160] [0160] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 35% to about 55% isopropanol. In aspects of that embodiment, a composition disclosed herein comprises about 5% to about 11% polyhexamethylene biguanide and about 37% to about 53% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 6% to about 10% of polyhexamethylene biguanide and about 40% to about 50% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% polyhexamethylene biguanide and about 42% to about 48% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 8% polyhexamethylene biguanide and about 45% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0161] [0161] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 30% to about 50% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 32% to about 48% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 35% to about 45% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 37% to about 43% of one or more alcohols.
[0162] [0162] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 30% to about 50% isopropanol. In aspects of this embodiment, a composition disclosed in the present document comprises about 5% to about 11% polyhexamethylene biguanide and about 32% to about 48% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% polyhexamethylene biguanide and about 35% to about 45% isopropanol. In yet other aspects of this embodiment, a composition disclosed in the present document comprises about 7% to about 9% polyhexamethylene biguanide and about 37% to about 43% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 8% polyhexamethylene biguanide and about 40% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0163] [0163] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide and about 25% to about 45% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 5% to about 11% of the compound containing biguanide and about 27% to about 43% of one or more alcohols. In other aspects of that embodiment, a composition disclosed herein comprises about 6% to about 10% of the compound containing biguanide and about 30% to about 40% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% of the compound containing biguanide and about 32% to about 38% of one or more alcohols.
[0164] [0164] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide and about 25% to about 45% isopropanol. In aspects of this embodiment, a composition disclosed herein comprises about 5% to about 11% polyhexamethylene biguanide and about 27% to about 43% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 6% to about 10% polyhexamethylene biguanide and about 30% to about 40% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 7% to about 9% polyhexamethylene biguanide and about 32% to about 38% isopropanol. In yet other aspects of this embodiment, a composition disclosed in the present document comprises about 8% polyhexamethylene biguanide and about 35% isopropanol. In other aspects of this modality, isopropanol can be replaced by a 5: 1 mixture at
[0165] [0165] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 60% to about 80% of one or more alcohols. In aspects of this embodiment, a composition disclosed in the present document comprises about 7% to about 13% of the compound containing biguanide and about 62% to about 78% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 8% to about 12% of the compound containing biguanide and about 65% to about 75% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 67% to about 73% of one or more alcohols.
[0166] [0166] In one embodiment, a composition disclosed herein comprises about 6% to about 15% polyhexamethylene biguanide and about 60% to about 80% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 7% to about 13% polyhexamethylene biguanide and about 62% to about 78% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 8% to about 12% polyhexamethylene biguanide and about 65% to about 75% isopropanol. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 9% to about 11% polyhexamethylene biguanide and about 67% to about 73% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 10% polyhexamethylene biguanide and about 70% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0167] [0167] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 55% to about 75% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 7% to about 13% of the compound containing biguanide and about 57% to about 73% of one or more alcohols. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% of the compound containing biguanide and about 60% to about 70% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 62% to about 68% of one or more alcohols.
[0168] [0168] In one embodiment, a composition disclosed herein comprises about 6% to about 15% polyhexamethylene biguanide and about 55% to about 75% isopropanol. In aspects of this embodiment, a composition disclosed in the present document comprises about 7% to about 13% polyhexamethylene biguanide and about 57% to about 73% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 8% to about 12% polyhexamethylene biguanide and about 60% to about 70% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% polyhexamethylene biguanide and about 62% to about 68% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 10% polyhexamethylene biguanide and about 65% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0169] [0169] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 50% to about 70% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 7% to about 13% of the compound containing biguanide and about 52% to about 68% of one or more alcohols. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% of the compound containing biguanide and about 55% to about 65% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 57% to about 63% of one or more alcohols.
[0170] [0170] In one embodiment, a composition disclosed herein comprises about 6% to about 15% polyhexamethylene biguanide and about 60% to about 70% isopropanol. In aspects of this embodiment, a composition disclosed herein comprises about 7% to about 13% polyhexamethylene biguanide and about 52% to about 68% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 8% to about 12% polyhexamethylene biguanide and about 55% to about 65% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% polyhexamethylene biguanide and about 57% to about 63% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 10% polyhexamethylene biguanide and about 60% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0171] [0171] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 45% to about 65% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 7% to about 13% of the compound containing biguanide and about 47% to about 63% of one or more alcohols. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% of the compound containing biguanide and about 50% to about 60% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 52% to about 58% of one or more alcohols.
[0172] [0172] In one embodiment, a composition disclosed herein comprises about 6% to about 15% polyhexamethylene biguanide and about 45% to about 65% isopropanol.
[0173] [0173] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 40% to about 60% of one or more alcohols. In aspects of this embodiment, a composition disclosed in the present document comprises about 7% to about 13% of the compound containing biguanide and about 42% to about 58% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 8% to about 12% of the compound containing biguanide and about 45% to about 55% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 47% to about 53% of one or more alcohols.
[0174] [0174] In one embodiment, a composition disclosed herein comprises about 6% to about 15% polyhexamethylene biguanide and about 40% to about 60% isopropanol. In aspects of that embodiment, a composition disclosed in the present document comprises about 7% to about 13% polyhexamethylene biguanide and about 42% to about 58% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% polyhexamethylene biguanide and about 45% to about 55% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% polyhexamethylene biguanide and about 47% to about 53% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 10% polyhexamethylene biguanide and about 50% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0175] [0175] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 35% to about 55% of one or more alcohols. In aspects of this embodiment, a composition disclosed herein comprises about 7% to about 13% of the compound containing biguanide and about 37% to about 53% of one or more alcohols. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% of the compound containing biguanide and about 40% to about 50% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 42% to about 48% of one or more alcohols.
[0176] [0176] In one embodiment, a composition disclosed herein comprises about 6% to about 15% polyhexamethylene biguanide and about 35% to about 55% isopropanol. In aspects of that embodiment, a composition disclosed herein comprises about 7% to about 13% polyhexamethylene biguanide and about 37% to about 53% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% of polyhexamethylene biguanide and about 40% to about 50% of isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% polyhexamethylene biguanide and about 42% to about 48% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 10% polyhexamethylene biguanide and about 45% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0177] [0177] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 30% to about 50% of one or more alcohols. In aspects of that embodiment, a composition disclosed in the present document comprises about 7% to about 13% of the compound containing biguanide and about 32% to about 48% of one or more alcohols. In other aspects of this embodiment, a composition disclosed herein comprises about 8% to about 12% of the compound containing biguanide and about 35% to about 45% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 37% to about 43% of one or more alcohols.
[0178] [0178] In one embodiment, a composition disclosed herein comprises about 6% to about 15% polyhexamethylene biguanide and about 30% to about 50% isopropanol. In aspects of this embodiment, a composition disclosed in the present document comprises about 7% to about 13% polyhexamethylene biguanide and about 32% to about 48% isopropanol. In other aspects of this embodiment, a composition disclosed in the present document comprises about 8% to about 12% polyhexamethylene biguanide and about 35% to about 45% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% polyhexamethylene biguanide and about 37% to about 43% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 10% polyhexamethylene biguanide and about 40% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0179] [0179] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide and about 25% to about 45% of one or more alcohols. In aspects of that embodiment, a composition disclosed herein comprises about 7% to about 13% of the compound containing biguanide and about 27% to about 43% of one or more alcohols. In other aspects of that embodiment, a composition disclosed herein comprises about 8% to about 12% of the compound containing biguanide and about 30% to about 40% of one or more alcohols. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% of the compound containing biguanide and about 32% to about 38% of one or more alcohols.
[0180] [0180] In one embodiment, a composition disclosed in this document comprises about 6% to about 15% polyhexamethylene biguanide and about 25% to about 45% isopropanol. In aspects of this embodiment, a composition disclosed in the present document comprises about 7% to about 13% polyhexamethylene biguanide and about 27% to about 43% isopropanol. In other aspects of this embodiment, a composition disclosed herein comprises about 8% to about 12% polyhexamethylene biguanide and about 30% to about 40% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 9% to about 11% polyhexamethylene biguanide and about 32% to about 38% isopropanol. In still other aspects of this embodiment, a composition disclosed herein comprises about 10% polyhexamethylene biguanide and about 35% isopropanol. In other aspects of this modality, isopropanol can be replaced by a mixture of 5: 1 to 1: 5 isopropanol: ethanol. In still other aspects of this embodiment, the compositions still comprise about 2% to about 7% cetylpyridinium chloride. In still other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0181] [0181] In one embodiment, a composition disclosed herein comprises about 6% to about 15% of the compound containing biguanide. In aspects of this embodiment, a composition disclosed herein comprises about 7% to about 13% of the compound containing biguanide.
[0182] [0182] In one embodiment, a composition disclosed in the present document comprises about 6% to about 15% polyhexamethylene biguanide. In aspects of this embodiment, a composition disclosed in the present document comprises about 7% to about 13% of polyhexamethylene biguanide.
[0183] [0183] In one embodiment, a composition disclosed herein comprises about 3% to about 13% of the compound containing biguanide. In aspects of this embodiment, a composition disclosed in the present document comprises about 5% to about 11% of the compound containing biguanide.
[0184] [0184] In one embodiment, a composition disclosed herein comprises about 3% to about 13% polyhexamethylene biguanide. In aspects of this modality,
[0185] [0185] In one embodiment, a composition disclosed herein comprises about 1% to about 10% of the compound containing biguanide. In aspects of this embodiment, a composition disclosed in the present document comprises about 3% to about 9% of the compound containing biguanide. In other aspects of this embodiment, a composition disclosed herein comprises about 4% to about 8% of the compound containing biguanide. In still other aspects of this embodiment, a composition disclosed herein comprises about 5% to about 7% of the compound containing biguanide. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 6% of compound containing biguanide. In other aspects of this modality, the compositions also comprise about 2% to about 7% of a quaternary ammonium surfactant. In still other aspects of this embodiment, the compositions are used to clean, disinfect and / or sterilize a device or a hard surface, as disclosed herein.
[0186] [0186] In one embodiment, a composition disclosed herein comprises from about 1% to about 10% of polyhexamethylene biguanide. In aspects of this embodiment, a composition disclosed in the present document comprises about 3% to about 9% of polyhexamethylene biguanide. In other aspects of this embodiment, a composition disclosed in the present document comprises about 4% to about 8% of polyhexamethylene biguanide. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 5% to about 7% of polyhexamethylene biguanide. In still other aspects of this embodiment, a composition disclosed in the present document comprises about 6% polyhexamethylene biguanide. In other aspects of this modality, the compositions are used to clean, disinfect and / or sterilize an endoscope, a heart-lung machine or a hard surface, as disclosed in this document.
[0187] [0187] Aspects of this specification reveal a kit. In one embodiment, the kit may comprise a container including a composition disclosed herein. In another embodiment, a kit may comprise one or more containers, wherein each container includes an individual component or more than one individual component disclosed in the present document in combination. For example, a kit can comprise a container including free available chlorine or hypochlorous acid and a second container including one or more disinfectants. As another example, a kit can comprise a container including one or more alcohols and a second container including one or more disinfectants. As yet another example, a kit can comprise a container that includes isopropanol and a second container that includes polyhexamethylene biguanide. As yet another example, a kit can comprise a container including a mixture of isopropanol and ethanol and a second container including polyhexamethylene biguanide. As another example, a kit can comprise a container that includes isopropanol, a second container that includes ethanol and a third container that includes polyhexamethylene biguanide.
[0188] [0188] In another example, a kit may comprise a container including hypochlorous acid and / or free available chlorine, a second container including one or more disinfectants and a third container including a rinse solution. As another example, a kit can comprise a container including one or more alcohols, a second container including one or more disinfectants and a third container including a rinse solution. As yet another example, a kit can comprise a container including isopropanol, a second container including polyhexamethylene biguanide and a third container including a rinse solution. As yet another example, a kit can comprise a container including a mixture of isopropanol and ethanol, a second container including polyhexamethylene biguanide and a third container including a rinse solution. As another example, a kit can comprise a container that includes isopropanol, a second container that includes ethanol, a third container that includes polyhexamethylene biguanide and a fourth container that includes a rinse solution. As another example, a kit can comprise a container that includes isopropanol, a second container that includes polyhexamethylene biguanide, a third container that includes one or more cationic surfactants and a fourth container that includes a rinse solution.
[0189] [0189] In another embodiment, a kit may comprise a container including a composition disclosed in this document and a second container including a rinse solution disclosed in this document. For example, a kit may comprise a container that includes hypochlorous acid and / or free available chlorine and one or more disinfectants and a second container that includes a rinse solution. As another example, a kit can comprise a container including one or more alcohols and one or more disinfectants and a second container including a rinse solution. As yet another example, a kit can comprise a container that includes isopropanol and polyhexamethylene biguanide and a second container that includes a rinse solution. As yet another example, a kit can comprise a container that includes a mixture of isopropanol and ethanol and polyhexamethylene biguanide and a second container that includes a rinse solution. As another example, a kit can comprise a container that includes isopropanol, polyhexamethylene biguanide and one or more cationic surfactant and a second container that includes a rinse solution. The remainder of the components of a composition disclosed in this document can be included in the first container or can be included separately in at least a third container. Packing individual components in a separate container can help extend the stability of the individual components and thus the product's life.
[0190] [0190] A kit disclosed in this document may comprise a delivery or application system. The delivery or application system of the kit is useful for applying a composition disclosed in this document and / or individual components disclosed in this document to a location of interest, such as, for example, a surface of a device disclosed in this document. A delivery or application system disclosed in this document includes, without limitation, one or more of an applicator brush, swab or porous foam pad, hollow tube, dipstick or a combination thereof. In one embodiment, a kit comprises a single application or delivery system. In another embodiment, a kit comprises a plurality of delivery or delivery systems. For example, in a 30-day supply kit, there can be 30 delivery or delivery systems, so there is one delivery or delivery system per day for 30 days. Alternatively, there can be 2, 10, 20, 30, 40, 50, 60, 90, 120, etc. kit delivery or application systems. Within the kit, the delivery or application system can be packed individually or in sets of 2 or more. The delivery or application system can be packaged to remain sterile until use. In certain embodiments, a delivery or delivery system disclosed in this document may be packaged in plastic sheaths. In addition, to avoid contamination, the delivery or application system disclosed in this document is preferably the single use disposable delivery or application system.
[0191] [0191] The kit can also include a set of instructions. The instructions may include information useful to the end user, such as using a delivery system or application to apply a composition and / or individual components disclosed in this document and / or how often to apply an individual composition and / or components disclosed in this document. . In addition, these instructions may include information on how to mix the individual components disclosed in this document to form a composition disclosed in this document. Such instructions may indicate that the mixing must be carried out at a certain time before application, such as, immediately before use. The instructions disclosed in this document may also include information on how to apply the individual components disclosed in this document directly to a location of interest, such as, for example, a surface of a device disclosed in this document and in which order the individual components should be applied to those places of interest.
[0192] [0192] The contents of the kit, including the container, including a composition or component disclosed in this document, the delivery or application system and instructions, are placed in an external coating. The outer wrapper can be a box, a sealed bag, a foil pouch, etc. In certain embodiments, the delivery system, container and instructions are enclosed in a box. In other modalities of the kit, the container and instructions are contained in a first box, the delivery system is contained in a second box and the first and second boxes are contained together in a third box.
[0193] [0193] Aspects of this specification reveal a method for cleaning, disinfecting and / or sterilizing a device, including a medical device. In one aspect of this embodiment, a method disclosed in this document comprises applying a composition disclosed in this document to a device for a specified period of time, in which the application results in cleaning,
[0194] [0194] Aspects of this specification reveal a method for cleaning, disinfecting and / or sterilizing an endoscope. In one aspect of this embodiment, a method disclosed in the present document comprises applying a composition disclosed in this document to an endoscope for a specified period of time, where the application results in cleaning, disinfecting and / or sterilizing the endoscope. In another aspect of this modality, a method disclosed in this document further comprises rinsing the clean, disinfected and / or sterilized endoscope with a rinse solution disclosed in this document. In other aspects, this specification discloses a composition disclosed in this document for use in cleaning, disinfecting and / or sterilizing an endoscope.
[0195] [0195] A device, including a medical device, is cleaned by removing visible soil, such as organic and inorganic material, from objects and surfaces and is usually carried out manually or mechanically. Thorough cleaning is essential before disinfection and sterilization, due to the fact that inorganic and organic materials that remain on the surfaces of a medical device interfere with the effectiveness of these processes.
[0196] [0196] A device, including a medical device, is disinfected by eliminating many or all pathogenic microorganisms, except bacterial spores.
[0197] [0197] A medical device is an instrument, apparatus, material or other article, used alone or in combination, including the software necessary for its application, intended by the manufacturer to be used by humans for diagnosis, prevention, treatment monitoring, or disease relief; diagnosis, monitoring, treatment or relief or compensation for an injury or disability; investigation, replacement or modification of anatomy or a physiological process; or control of conception and that does not reach its intended primary action in the human body by pharmacological, immunological or metabolic means, but can be aided in its function by these means. A medical device includes, without limitation, a surgical instrument, a respiratory therapy instrument, an anesthesia instrument, a catheter, an implant, a probe, an endoscope, an arthroscope, a laparoscope, a blade, a cystoscope, a spirometer, a CPAP mask and tube, dialysis instrument and accessories, heart-lung accessories and machine, accessories and heart-lung bypass machine and a diaphragm adjustment ring. Non-limiting examples of a probe include an ultrasound probe and an esophageal manometry probe.
[0198] [0198] Aspects of this specification reveal a method for cleaning, disinfecting and / or sterilizing a hard surface area. In one aspect of this embodiment, a method disclosed in the present document comprises applying a composition disclosed in this document to a hard surface area for a specified period of time, where the application results in cleaning, disinfecting and / or sterilizing the area hard surface.
[0199] [0199] In another aspect of this modality, a method disclosed in this document comprises the application of one or more individual components disclosed in this document to a hard surface area for a specified period of time, in which the application results in cleaning, disinfection and / or sterilizing the hard surface area. In one aspect of this embodiment, the one or more individual components include a first component including available free chlorine or hypochlorous acid and a second component including one or more disinfectants. In another aspect, the application of one or more individual components occurs in a specific order, such as, for example, first applying a first component including hypochlorous acid or free available chlorine and then applying a second component including one or more disinfectants. A hard surface area can be a porous surface area or a non-porous surface area.
[0200] [0200] A hard surface area can include any items present in a residence or commercial, industrial and / or agricultural facility, such as a hospital, laboratory, restaurant, educational center, processing facility food processing, a dairy processing facility, an airport, an oilfield system, a sports facility, an export dock, a cargo transportation center, or any other commercial or industrial environment.
[0201] [0201] A composition or component disclosed in this document can be applied to a hard surface area according to a method disclosed in this document as many times as necessary and / or desired. A composition disclosed in this document can be applied to a hard surface area daily, every other day, every third of the day, once a week, several times a week, once a month, several times a month, once per year or several times per year, as desired. A composition disclosed in this document can be applied to a hard surface area several times a day, for example, twice a day, three times a day, four times a day, five times a day, six times a day or as many times Wish.
[0202] [0202] Aspects of this specification reveal a method for cleaning, disinfecting and / or sterilizing a microbial infection in an individual. In one aspect of this embodiment, a method disclosed in this document comprises applying a composition disclosed in this document to an individual for a specified period of time, where the application results in the cleaning, disinfection and / or sterilization of a microbial infection in the individual. Other aspects, this specification discloses a composition disclosed in this document for use in cleaning, disinfecting and / or sterilizing a microbial infection in an individual. In still other aspects, this specification discloses the use of a disclosed composition to clean, disinfect and / or sterilize a microbial infection in an individual. In still other aspects, the present specification discloses a composition disclosed in the present document for the manufacture of a drug to clean, disinfect and / or sterilize a microbial infection in an individual.
[0203] [0203] A method and / or use disclosed in this document cleans, disinfects and / or sterilizes a microbial infection. A microbial infection includes a viral infection, a bacterial infection and a yeast infection.
[0204] [0204] A method and / or use disclosed in this document applies a composition disclosed in this document to an individual. An individual refers to any animal, including, without limitation, a fish, an amphibian, a bird and a mammal. A mammal includes a human, a horse, a cow, a sheep, a dog and a cat. As such, a method disclosed in this document is for human as well as veterinary use.
[0205] [0205] In applications to an individual, a composition disclosed in this document can be applied to a skin surface or can be administered internally. In one embodiment, a composition disclosed in this document is applied topically to an individual's skin region in order to clean, disinfect and / or sterilize the skin region. A region of the skin includes, without limitation, the face, forehead, lips, scalp, neck, shoulder, arms, hands, thighs, legs, knees, feet, chest, chest, back, groin, buttocks and the like.
[0206] [0206] In one embodiment, a composition disclosed in this document is administered internally to an individual. Such routes of administration include enteral routes of administration and parenteral routes of administration.
[0207] [0207] A composition disclosed in this document can be applied according to a method disclosed in this document to a region of the skin. The application of a composition disclosed in this document may be by rubbing, pouring, spraying or spraying on, or otherwise applied to, the human body. A composition disclosed in this document can be applied by inserting the composition on or on a solid support, such as, for example, a towel, a towel, a towel, a glove, a glove or a mask and then applying the composition to a region of the skin. A composition disclosed in this document can be applied using a delivery device, such as an aerosol dispenser, a pump spray, a trigger sprinkler, a compression bottle, a topical adhesive, a transdermal patch or an implant dermal to apply the composition to a region of the skin.
[0208] [0208] A composition disclosed in this document can be applied to an individual according to a method disclosed in this document as many times as necessary and / or desired. A composition disclosed in this document can be applied to an individual daily, every other day, every third of the day, once a week, several times a week, once a month, several times a month, once a year or several times a year, as desired. A composition disclosed in this document can be applied to an individual several times a day, for example, twice a day, three times a day, four times a day, five times a day, six times a day or as many times as desired.
[0209] [0209] A disclosed method and / or use applies a disclosed composition in this document for a specified period of time. In one embodiment, a specified amount of time is sufficient time to clean a medical device, a surface, or an individual. In another embodiment, a specified amount of time is sufficient time to disinfect a medical device, a surface or an individual. In yet another embodiment, a specified amount of time is sufficient time to sterilize a medical device, a surface, or an individual.
[0210] [0210] In aspects of this embodiment, a composition disclosed in this document is applied to a device, such as a medical device, a surface or an individual for, for example, about 1 minute, about 5 minutes, about 10 minutes, about 15 minutes, about 20 minutes, about 25 minutes, about 30 minutes, about 35 minutes, about 40 minutes, about 45 minutes, about 50 minutes, about 55 minutes, about 60 minutes, about 70 minutes, about 80 minutes, about 90 minutes, about 100 minutes, 110 minutes or 120 minutes.
[0211] [0211] In still other aspects of this modality, a composition disclosed in the present document is applied to a device, such as a medical device, a surface or an individual for, for example, about 1 minute to about 5 minutes, about 1 minute to about 10 minutes, about 1 minute to about 15 minutes, about 1 minute to about 20 minutes, about 1 minute to about 25 minutes, about 1 minute to about 30 minutes, about 1 minute to about 35 minutes, about 1 minute to about 40 minutes, about 1 minute to about 45 minutes, about 1 minute to about 50 minutes, about 1 minute to about 55 minutes, about 1 minute to about 60 minutes, about 5 minutes to about 10 minutes, about 5 minutes to about 15 minutes,
[0212] [0212] A disclosed composition, method and / or use is less severe on a medical device, resulting in longer use of the medical device.
[0213] [0213] In still other aspects of this modality, a medical device can be cleaned, disinfected and / or sterilized, for example, about 50 times to about 60 times, about 50 times to about 70 times, about 50 to about 80 times, about 50 times to about 90 times, about 50 times to about 100 times, about 50 times to about 110 times, about 50 times to about 120 times, about 50 times to about 130 times, about 50 times about 140 times, about 50 times about 150 times, about 50 times about 175 times, about 50 times about 200 times, about 50 times about 225 times, about 50 times to about 250 times, about 50 times to about 275 times, about 50 times to about 300 times,
[0214] [0214] A method disclosed in this document may further comprise a rinse step using a rinse solution. Typically, the rinse solution is used to rinse a clean, disinfected and / or sterilized medical device or surface. The rinse solution is preferably a sterile solution. In one embodiment, a rinse solution disclosed in this document comprises water. In another embodiment, a rinse solution disclosed in this document comprises hypochlorous acid or freely available chlorine and water. In another embodiment, a rinse solution disclosed in this document does not comprise hypochlorous acid and / or free available chlorine. When present in a kit disclosed in this document, the rinse solution is present in a separate container.
[0215] [0215] The amount of available hypochlorous acid or free chlorine present in a rinse solution disclosed herein is any amount that provides an antimicrobial effect, with the proviso that the total amount of available available hypochlorous acid or chlorine is an amount below the threshold level that results in the oxidation of a surface medical device, as disclosed in this document. In aspects of this modality, the amount of available free hypochlorous acid or chlorine present in a rinse solution can be, for example, about 5 ppm, about 10 ppm, about 20 ppm, about 30 ppm, about 40 ppm , about 50 ppm, about 60 ppm, about 70 ppm, about 80 ppm, about 90 ppm, about 100 ppm, about 110 ppm, or about 120 ppm. In other aspects of this modality, the amount of available hypochlorous acid or free chlorine present in a rinse solution can be, for example, a maximum of 5 ppm, a maximum of 10 ppm, a maximum of 20 ppm, a maximum of 30 ppm, a maximum of 40 ppm, maximum 50 ppm, maximum 60 ppm, maximum 70 ppm, maximum 80 ppm, maximum 90 ppm, maximum 100 ppm, maximum 110 ppm or maximum 120 ppm. In yet other aspects of this modality, the amount of available free hypochlorous acid or chlorine present in a rinse solution can be, for example, about 5 ppm to about 10 ppm,
[0216] [0216] The following non-limiting examples are provided for illustrative purposes only, in order to facilitate a more complete understanding of the representative modalities now contemplated. These examples should not be interpreted to limit any of the modalities described in this specification, including those pertaining to the compositions, methods and uses disclosed in this document.
[0217] [0217] This example illustrates how to formulate a composition revealed in this document. The components listed below were mixed at room temperature using a high shear mixer until the mixture was uniform. The pH of the mixture was adjusted as shown. For amounts of hypochlorous acid, unless otherwise stated, the amount is the final concentration after mixing with other components.
[0218] [0218] This example illustrates how to conduct a spore viability assay using compositions disclosed in this document.
[0219] [0219] To prepare pathogenic spore stock cultures, 10 ml of nutrient broth were inoculated using a stock culture of Bacillus subtilis (ATCC No. 19659) and incubated on an orbital shaker for 24 ± 2 hours at approximately 150 rpm at 36 ± 1 ºC. This culture was used to inoculate plates of Triptych Soy Agar (TSA). Each plate was inoculated with 500 µl of broth culture and the inoculum spread with a sterile L spreader.
[0220] [0220] The test samples were assembled with or without serum, such as, for example, Triptych Soy Broth (TSB) or Bovine Serum (BS). The purpose of the serum was to better simulate the organic load of blood and other tissues that tend to deactivate an antimicrobial agent. In general, assays were conducted by first incubating a sample of pathogen spores with a composition disclosed in this document for a specified period of treatment time, optionally with serum, and then culturing the sample in growth medium to assess spore viability. .
[0221] [0221] In a series of experiments, the assays in which the samples were treated with serum were set up to contain 100 µl of pathogen spore suspension (containing about 1 x 106 cfu / ml), 50 µl of serum and 850 µl of a composition described in Example 1. For assays in which the samples were not treated with serum, the samples contained 100 µl of pathogen spore suspension (containing about 1 x 106 cfu / ml) and 900 µl of a composition described in Example 1. All samples were incubated for 15 minutes and then seeded in Petri dishes containing TSA growth medium. The inoculated plates were incubated at 37 ºC for 48 hours and the number of bacterial colonies, if any, was counted. Note that, while specific quantities and volumes are described, different quantities and volumes can be used. For example, a treated sample may contain 100 ml of pathogen spore suspension (containing about 1 x 10 6 cfu / ml), 500 µl of serum, and 9,400 µl of a composition described herein. An untreated sample can contain 100 µl of pathogen spore suspension (containing about 1 x 10 6 cfu / ml) and 9,900 µl of a composition described herein.
[0222] [0222] The results of this series of experiments are shown in Table 16. The results indicate that Compositions F4, F6, F13, F14, F42, F45, F45, F80, F83, F88, F89 and F90 have greater potential as a disinfectant for applications involving hard surfaces, devices and other devices. Compositions that did not show growth in the treated samples were selected for further analysis, as described in Example 3.
[0223] [0223] This example illustrates how to conduct a spore viability assay using compositions disclosed in this document.
[0224] [0224] Spore suspensions of stock pathogens were prepared as described in Example 2.
[0225] [0225] In a series of experiments, the test samples were prepared as described in Example 2, except that only the treated samples were prepared for each composition, the samples were incubated for 30 minutes, a neutralizing agent was used to inhibit the activity of the microbial agent being tested, for each treatment period the samples were diluted in series 1 in 10, in a range of 6 times after treatment with a neutralizing agent, and the treated sample was seeded in Petri dishes containing TSA growth medium , incubated at 30 ºC to 35 ºC for 5 days and the number of bacterial colonies, if any, counted. The purpose of the neutralizing agent, such as Dey-Engley Broth (DE), was to deactivate an antimicrobial agent such as hypochlorous acid, polyhexamethylene biguanide and / or another agent whose activity functions as a cleaner, disinfectant or sterilizer, thereby improving accuracy of point-in-time measurement.
[0226] [0226] The results are shown in Table 17.
[0227] [0227] In another series of experiments, the test samples were prepared as described in Example 2, except that only the treated samples were prepared for each composition, the samples were incubated for 30 minutes, 500 µl of pathogenic spore suspension containing about 5 x 106 cfu / ml was used for Composition F60, a neutralizing agent was used to inhibit the activity of the microbial agent being tested, for each treatment period the samples were diluted in series 1 in 10 in a range of 6 times after the treatment with a neutralizing agent, and the treated sample was sown in Petri dishes containing TSA growth medium, incubated at 35 ºC ± 2 ºC for 2 days and counting the number of bacterial colonies, if any.
[0228] [0228] The results are shown in Table 18.
[0229] [0229] This example illustrates how to conduct composition stability studies using compositions disclosed in this document.
[0230] [0230] Pathogenic spore stock suspensions were prepared as described in Example 2.
[0231] [0231] In a series of experiments, the compositions disclosed in this document were prepared, loaded into a bottle and stored at room temperature for 6 months. Test samples of the stored bottle compositions were prepared as described in Example 2, except that only treated samples were prepared for each composition, the samples were incubated for 30 minutes, the spore suspension of pathogens contained about 1 x 108 cfu / ml, a neutralizing agent was used to inhibit the activity of the microbial agent being tested, for each treatment period the samples were diluted in series 1 in 10, in a range of 6 times after treatment with a neutralizing agent, and the treated sample it was coated in Petri dishes containing TSA growth medium, incubated from 30 ºC to 35 ºC for 5 days and the number of bacterial colonies, if any, counted on the second day of incubation.
[0232] [0232] The results are shown in Table 19.
[0233] [0233] This example illustrates how to conduct composition stability studies using compositions disclosed in this document.
[0234] [0234] Clostridium difficile pathogenic bacteria stock suspensions were prepared by a laboratory contracted by third parties, in accordance with industry standard procedures.
[0235] [0235] In a series of experiments, test samples of the compositions were prepared as described in Example 2, except that only treated samples were prepared for each composition, the samples were incubated for 1 minute, a neutralizing agent was used to inhibit the activity of the microbial agent being tested, for each treatment period the samples were diluted in series 1 in 10, in a range of 6 times after treatment with a neutralizing agent, and the treated sample was bathed in Petri dishes containing TSA growth medium , incubated at 30 ºC to 35 ºC for 2 days and the number of bacterial colonies, if any, was counted.
[0236] [0236] The results are shown in Table 20.
[0237] [0237] Spore suspensions of stock pathogens were prepared as described in Example 2.
[0238] [0238] A test assay was set up by placing an endoscope in a sterile container inside a biosafety cabinet and inoculating this device with 4.0 ml of a test inoculum solution comprising 1 x 106 cfu / ml of the pathogenic spore suspension. over 5% organic soil was used to simulate the level of contamination of the endoscope in clinical use. The dirty endoscope was then removed from the test inoculum solution and air dried for one hour. The dirty device was then transferred to a sterile plastic container inside a biosafety cabinet and cleaned with Composition F60 (see Example 1).
[0239] [0239] The F60 composition showed a 6 log reduction in the viability of B. subtilis spores. The results indicate that formulation F60 effectively disinfected a device inoculated at an exposure time not exceeding 30 minutes.
[0240] [0240] To conclude, it should be understood that, although aspects of this specification are highlighted by reference to specific modalities, one skilled in the art will readily appreciate that these revealed modalities are only illustrative of the principles of the subject disclosed in this document. Therefore, it should be understood that the material disclosed is not limited to a particular compound, composition, article, apparatus, methodology, protocol and / or reagent, described herein, unless expressly stated as such. In addition, those skilled in the art will recognize that certain changes, modifications, exchanges, alterations, additions, subtractions and subsets can be made in accordance with the teachings contained herein, without departing from the spirit of this specification. It is intended, therefore, that the following amended claims and claims presented below are interpreted to include all such changes, modifications, exchanges, alterations, additions, subtractions and subsets that are within their true spirit and scope.
[0241] [0241] Certain embodiments of the present invention are described here, including the best way known to the inventors for carrying out the invention. Obviously, variations in these described modalities will be evident to those skilled in the art after reading the previous description. The inventor expects those skilled in the art to employ such variations as appropriate, and the inventors intend that the present invention be practiced in a manner other than specifically described herein. Accordingly, this invention includes all modifications and equivalents of the object recited in the amended claims, as permitted by applicable law. In addition, any combination of the modalities described above in all possible variations is covered by the invention, unless otherwise indicated here or clearly contradicted by the context.
[0242] [0242] The groupings of modalities, elements or alternative stages of the present invention should not be interpreted as limitations. Each group member can be referred to and claimed individually or in any combination with other group members disclosed in this document. It is envisaged that one or more members of a group may be included or excluded from a group for reasons of convenience and / or patentability. When any inclusion or exclusion occurs, the specification is considered to contain the modified group, thus fulfilling the written description of all Markush groups used in the amended claims.
[0243] [0243] Unless otherwise indicated, all numbers expressing a characteristic, item, quantity, parameter, property, term and so on used in this specification and claims must be understood as modified in all instances by the term “about ”. As used herein, the term “about” means that the characteristic, item, quantity, parameter, property or term so qualified covers a range of plus or minus ten percent above and below the declared characteristic, item, quantity, parameter value , property or term. Therefore, unless otherwise indicated, the numerical parameters set out in the specification and in the amended claims are approximations that may vary. For example, since mass spectrometry instruments can vary slightly in determining the mass of a given analyte, the term “about” in the context of the mass of an ion or the mass / charge ratio of an ion refers to + / - 0.50 atomic mass unit. At a minimum, and not as an attempt to limit the application of the doctrine of equivalents to the scope of the claims, each numerical indication should at least be interpreted in light of the number of significant digits reported and applying common rounding techniques.
[0244] [0244] The use of the terms "must" or "can" in reference to a modality or aspect of a modality also brings with it the alternative meaning of "must not" or "cannot". As such, if the present specification reveals that a modality or an aspect of a modality can be or can be included as part of the inventive object, then the negative limitation or exclusion condition is also explicitly understood, meaning that a modality or aspect of a modality may or may not be included as part of the inventive object. Similarly, the use of the term "optionally" in reference to a modality or aspect of a modality means that that modality or aspect of the modality can be included as part of the inventive object or cannot be included as part of the inventive material. The application of such negative limitation or exclusion condition will be based on the recitation of the negative limitation or exclusion on the claimed object.
[0245] [0245] Although the numerical ranges and values that establish the broad scope of the invention are approximations, the numerical ranges and values established in the specific examples are reported as accurately as possible. Any range or numerical value, however, inherently contains certain errors necessarily resulting from the standard deviation found in their respective test measurements. The recitation of numerical ranges of values in this document is only intended to serve as an abbreviated method of referring individually to each separate numerical value within the range. Unless otherwise indicated here, each individual value in a numerical range is incorporated into this specification as if it were recited here individually.
[0246] [0246] The terms “um”, “uma”, “o / a” and similar references used in the context of the description of the present invention (especially in the context of the following claims) should be interpreted to cover both the singular and the plural, unless otherwise indicated here or clearly contradicted by the context. In addition, ordinal indicators - such as "first", "second", "third", etc. - for identified elements they are used to distinguish between the elements and do not indicate or imply a necessary or limited number of such elements and do not indicate a specific position or order of such elements, unless otherwise specified. All methods described herein may be performed in any suitable order, unless otherwise indicated here or clearly contradicted by the context. The use of any example or exemplary language (for example, "how") provided herein is intended only to better illuminate the present invention and does not represent a limitation on the scope of the otherwise claimed invention. No language in this specification should be construed to indicate any unclaimed elements essential to the practice of the invention.
[0247] [0247] When used in the claims, presented or added by amendment, the open transitional term "comprises" (and its equivalent open transitional expressions, such as include, contain and have), encompasses all elements expressly recited, limitations, steps and / or resources alone or in combination with the unspecified subject; the named elements, limitations and / or features are essential, but other unnamed elements, limitations and / or features can be added and still form a construction within the scope of the claim.
[0248] [0248] All patents, patent publications and other publications referenced and identified in this specification are incorporated individually and expressly here for reference in their entirety, with the aim of describing and revealing, for example, the compositions and methodologies described in those publications that can be used in connection with the present invention. These publications are provided for disclosure only prior to the filing date of this application. Nothing in this regard should be construed as an admission that inventors have no right to precede this disclosure by virtue of a previous invention or for any other reason. All statements regarding the date or representation regarding the content of these documents are based on the information available to applicants and do not constitute any admission as to the accuracy of the dates or the content of these documents.
[0249] [0249] Finally, the terminology used in this document is intended to describe only particular modalities and is not intended to limit the scope of the present invention, which is defined only by the claims. Therefore, the present invention is not limited to that exactly as shown and described.

权利要求:
Claims (5)
[1]
1. Composition characterized by the fact that it comprises, essentially consists of, or consists of available hypochlorous acid or free chlorine and one or more disinfectants.
[2]
2. Composition according to claim 1, characterized by the fact that the available hypochlorous acid or free chlorine is in an amount of about 0.00005%, about 0.00006%, about 0.00007%, about 0.000075%, about 0.00008%, about 0.00009%, about 0.0001%, about 0.0005%, about 0.001%, about 0.0015%, about 0.002 %, about 0.0025%, about 0.003%, about 0.0035%, about 0.004%, about 0.0045%, about 0.005%, about 0.0055%, about 0.006%, about 0.007%, about 0.0075%, about 0.008%, about 0.009%, about 0.01%, about 0.02%, about 0.03%, about 0.04%, about 0.05%, about 0.06%, about 0.07%, about 0.075%, about 0.08%, about 0.09%, about 0.10%, about 0 , 11%, about 0.12%, about 0.13%, about 0.14% or about 0.15% by weight of the composition, or at least 0.00005%, at least 0.00006% at least 0.00007%, at least 0.000075%, at least 0.00008%, at least 0.00009%, at least 0.0001%, at least at least 0.0005%, at least 0.001%, at least 0.0015%, at least 0.002%, at least 0.0025%, at least 0.003%, at least 0.0035%, at least 0.004%, at least 0 , 0045%,
at least 0.005%, at least 0.0055%, at least 0.006%,
at least 0.007%, at least 0.0075%, at least 0.008%,
at least 0.009%, at least 0.01%, at least 0.02%, at least 0.03%, at least 0.04%, at least 0.05%, at least
0.06%, at least 0.07%, at least 0.075%, at least 0.08%,
at least 0.09%, at least 0.10%, at least 0.11%, at least 0.12%, at least 0.13%, at least 0.14% or at least
0.15% by weight of the composition, or a maximum of 0.00005%, a maximum
0.00006%, maximum 0.00007%, maximum 0.000075%, maximum
0.00008%, maximum 0.00009%, maximum 0.0001%, maximum
0.0005%, maximum 0.001%, maximum 0.0015%, maximum
0.002%, maximum 0.0025%, maximum 0.003%, maximum
0.0035%, maximum 0.004%, maximum 0.0045%, maximum
0.005%, maximum 0.0055%, maximum 0.006%, maximum
0.007%, maximum 0.0075%, maximum 0.008%, maximum
0.009%, maximum 0.01%, maximum 0.02%, maximum 0.03%,
maximum 0.04%, maximum 0.05%, maximum 0.06%, maximum
0.07%, maximum 0.075%, maximum 0.08%, maximum 0.09%,
maximum 0.10%, maximum 0.11%, maximum 0.12%, maximum
0.13%, maximum 0.14% or maximum 0.15% by weight of the composition or about 0.00075% to about 0.002%, about
0.00075% to about 0.003%, about 0.00075% to about
0.004%, about 0.00075% to about 0.005%, about
0.00075% to about 0.006%, about 0.00075% to about
0.007%, about 0.00075% to about 0.008%, about
0.00075% to about 0.009%, about 0.00075% to about 0.01%, about 0.001% to about 0.002%, about 0.001% to about 0.003%, about 0.001% to about from 0.004%, about 0.001% to about 0.005%, about 0.001% to about 0.006%, about 0.001% to about 0.007%, about 0.001% to about 0.008%, about 0.001% to about from 0.009%, about 0.001% to about 0.01%, about 0.002% to about 0.003%, about 0.002% to about 0.004%, about 0.002% to about 0.005%, about 0.002% about 0.006%, about 0.002% to about 0.007%, about 0.002% to about 0.008%, about 0.002% to about 0.009%, about 0.002% to about 0.01% by weight of composition.
[3]
3. Composition according to claim 1, characterized by the fact that the available free chlorine or hypochlorous acid is in an amount of 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0, 25 ppm, 0.30 ppm, 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0, 75 ppm, 0.80 ppm, 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm , 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1,000 ppm, 1,025 ppm, 1,050 ppm, 1,075 ppm, 1,100 ppm, 1,125 ppm, 1,150 ppm, 1,175 ppm, 1,200 ppm, 1,225 ppm,
1,250 ppm, 1,275 ppm, 1,300 ppm, 1,325 ppm, 1,350 ppm, 1,375 ppm, 1,400 ppm, 1,425 ppm, 1,450 ppm, 1,475 ppm or 1,500 ppm, or at least 0.05 ppm, at least 0.10 ppm, at least 0.20 ppm, at least 0.30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least 0.80 ppm, at least 0 , 90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm, at least 40 ppm, at least 50 ppm, at least 60 ppm, at least 70 ppm, at least 80 ppm, at least least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1,000 ppm, at least 1,025 ppm, at least 1,050 ppm, at least 1,075 ppm, at least 1,100 ppm, at least
1,125 ppm, at least 1,150 ppm, at least 1,175 ppm, at least 1,200 ppm, at least 1,225 ppm, at least 1,250 ppm, at least 1,275 ppm, at least 1,300 ppm, at least 1,325 ppm, at least 1,350 ppm, at least 1,375 ppm at least
1,400 ppm, at least 1,425 ppm, at least 1,450 ppm, at least 1,475 ppm or at least 1,500 ppm, or at most 0.05 ppm, at most 0.10 ppm, at most 0.20 ppm, at most 0.30 ppm, maximum 0.40 ppm, maximum 0.50 ppm, maximum 0.60 ppm, maximum 0.70 ppm, maximum 0.80 ppm, maximum 0.90 ppm, maximum 1 ppm, no maximum 10 ppm, maximum 20 ppm, maximum 30 ppm, maximum 40 ppm, maximum 50 ppm, maximum 60 ppm, maximum 70 ppm, maximum 80 ppm, maximum 90 ppm, maximum 100 ppm, no maximum 125 ppm, maximum 150 ppm, maximum 175 ppm, maximum 200 ppm, maximum 225 ppm, maximum 250 ppm, maximum 275 ppm, maximum 300 ppm, maximum 325 ppm, maximum 350 ppm, no maximum 375 ppm, maximum 400 ppm, maximum 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm, maximum 550 ppm, maximum 575 ppm, maximum 600 ppm, no maximum 625 ppm, maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, m maximum 775 ppm, maximum 800 ppm, maximum 825 ppm, maximum 850 ppm, maximum 875 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm, maximum 1,000 ppm maximum 1,025 ppm maximum
1,050 ppm, at most 1,075 ppm, at most 1,100 ppm, at most 1,125 ppm, at most 1,150 ppm, at most 1,175 ppm, at most 1,200 ppm, at most 1,225 ppm, at most 1,250 ppm, at most 1,275 ppm, at most 1,300 ppm maximum
1,325 ppm, at most 1,350 ppm, at most 1,375 ppm, at most 1,400 ppm, at most 1,425 ppm, at most 1,450 ppm, at most 1,475 ppm or at most 1,500 ppm, or about 0.5 ppm at about 20 ppm, about 0.5 ppm to about 25 ppm, about 0.5 ppm to about 30 ppm, about 0.5 ppm to about 35 ppm, about 0.5 ppm to about 40 ppm, about 0.5 ppm to about 45 ppm, about 0.5 ppm to about 50 ppm, about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 60 ppm, about 0, 5 ppm to about 65 ppm, about 0.5 ppm to about 70 ppm, about 0.5 ppm to about 75 ppm, about 0.5 ppm to about 80 ppm, about 0.5 ppm at about 85 ppm, about 0.5 ppm to about 90 ppm, about 0.5 ppm to about 95 ppm, about 0.5 ppm to about 100 ppm, about 0.75 ppm to about 20 ppm, about 0.75 ppm to about 25 ppm, about 0.75 ppm to about 30 ppm, about 0.75 ppm to about 35 ppm, about 0.75 ppm to about 40 ppm, about 0.75 ppm to about 45 ppm, about from 0.75 ppm to about 50 ppm, about 0.75 ppm to about 55 ppm, about 0.75 ppm to about 60 ppm, about 0.75 ppm to about 65 ppm, about 0.75 ppm to about 70 ppm, about 0.75 ppm to about 75 ppm, about 0.75 ppm to about
80 ppm, about 0.75 ppm to about 85 ppm, about 0.75 ppm to about 90 ppm, about 0.75 ppm to about 95 ppm,
about 0.75 ppm to about 100 ppm, about 1 ppm to about 20 ppm, about 1 ppm to about 25 ppm, about 1 ppm to about 30 ppm, about 1 ppm to about 35 ppm, about 1 ppm to about 40 ppm, about 1 ppm to about 45 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 55 ppm, about 1 ppm to about 60 ppm, about 1 ppm to about 65 ppm, about 1 ppm to about 70 ppm, about 1 ppm to about 75 ppm, about 1 ppm to about 80 ppm, about 1 ppm to about 85 ppm, about 1 ppm to about 90 ppm, about 1 ppm to about 95 ppm, about 1 ppm to about 100 ppm, about 5 ppm to about 20 ppm, about 5 ppm to about 25 ppm, about 5 ppm to about 30 ppm, about 5 ppm to about 35 ppm, about 5 ppm to about 40 ppm, about 5 ppm to about 45 ppm, about 5 ppm to about 50 ppm, about 5 ppm to about 55 ppm, about 5 ppm to about 60 ppm, about 5 ppm to about 65 ppm, about 5 ppm to about 70 ppm, about 5 ppm to about 75 ppm, about 5 ppm to about 80 ppm, about 5 ppm to about 85 ppm, about 5 ppm to about 90 ppm, about 5 ppm to about 95 ppm, about 5 ppm to about 100 ppm, about 10 ppm to about 20 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 30 ppm, about
10 ppm to about 35 ppm, about 10 ppm to about 40 ppm,
about 10 ppm to about 45 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 55 ppm, about 10 ppm to about 60 ppm, about 10 ppm to about 65 ppm,
about 10 ppm to about 70 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 80 ppm, about 10 ppm to about 85 ppm, about 10 ppm to about 90 ppm,
about 10 ppm to about 95 ppm, or about 10 ppm to about 100 ppm or about 1 ppm to about 25 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 75 ppm ,
about 1 ppm to about 100 ppm, about 1 ppm to about
125 ppm, about 1 ppm to about 150 ppm, about 1 ppm to about 175 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, about 1 ppm to about 250 ppm, about 1 ppm to about 275 ppm, about 1 ppm to about 300 ppm, about 1 ppm to about 325 ppm, about 1 ppm to about 350 ppm, about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about
10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, about 10 ppm to about 125 ppm, about 10 ppm to about 150 ppm, about 10 ppm to about 175 ppm, about 10 ppm to about 200 ppm, about 10 ppm to about 225 ppm, about 10 ppm to about 250 ppm, about 10 ppm to about 275 ppm, about 10 ppm to about 300 ppm, about 10 ppm to about 325 ppm, about 10 ppm to about 350 ppm, about 10 ppm to about 375 ppm, about 10 ppm to about 400 ppm, about 25 ppm to about 50 ppm, about 25 ppm to about 75 ppm, about 25 ppm to about 100 ppm, about 25 ppm to about 125 ppm, about 25 ppm to about 150 ppm, about 25 ppm to about 175 ppm, about 25 ppm to about 200 ppm, about 25 ppm to about 225 ppm, about 25 ppm to about 250 ppm, about 25 ppm to about 275 ppm, about 25 ppm to about 300 ppm, about 25 ppm to about 325 ppm, about 25 ppm to about 350 ppm, about 25 ppm to about 375 ppm, about from 25 ppm to about 400 ppm, about 50 ppm to about 75 ppm, about 50 ppm to about 100 ppm, about 50 ppm to about 125 ppm, about 50 ppm to about 150 ppm, about 50 ppm to about 175 ppm, about 50 ppm to about 200 ppm, about 50 ppm to about 225 ppm, about 50 ppm to about 250 ppm, about 50 ppm to about 275 ppm, about 50 ppm to about 300 ppm, about 50 ppm to about 325 ppm, about 50 ppm to about 350 ppm, about 50 ppm to about 375 ppm, about 50 ppm to about 400 ppm, about 75 ppm to about 100 ppm, about 75 ppm to about 125 ppm, about 75 ppm to about 150 ppm, about 75 ppm to about 175 ppm, about 75 ppm to about 200 ppm, about 75 ppm to about 225 ppm, about 75 ppm to about 250 ppm, about 75 ppm to about 275 ppm, about 75 ppm to about 300 ppm, about 75 ppm to about 325 ppm, about 75 ppm to about 350 ppm, about 75 ppm to about 375 ppm, about 75 ppm to about 400 pp m, about 100 ppm to about
125 ppm, about 100 ppm to about 150 ppm, about 100 ppm to about 175 ppm, about 100 ppm to about 200 ppm,
about 100 ppm to about 225 ppm, about 100 ppm to about 250 ppm, about 100 ppm to about 275 ppm, about
100 ppm to about 300 ppm, about 100 ppm to about 325 ppm, about 100 ppm to about 350 ppm, about 100 ppm to about 375 ppm, about 100 ppm to about 400 ppm,
about 150 ppm to about 175 ppm, about 150 ppm to about 200 ppm, about 150 ppm to about 225 ppm, about
150 ppm to about 250 ppm, about 150 ppm to about 275 ppm, about 150 ppm to about 300 ppm, about 150 ppm to about 325 ppm, about 150 ppm to about 350 ppm,
about 150 ppm to about 375 ppm, about 150 ppm to about 400 ppm, about 200 ppm to about 225 ppm, about
200 ppm to about 250 ppm, about 200 ppm to about 275 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 325 ppm, about 200 ppm to about 350 ppm,
about 200 ppm to about 375 ppm, about 200 ppm to about 400 ppm, about 250 ppm to about 275 ppm, about
250 ppm to about 300 ppm, about 250 ppm to about 325 ppm, about 250 ppm to about 350 ppm, about 250 ppm to about 375 ppm, about 250 ppm to about 400 ppm,
about 300 ppm to about 325 ppm, about 300 ppm to about 350 ppm, about 300 ppm to about 375 ppm, about 300 ppm to about 400 ppm, about 350 ppm to about 375 ppm, about 350 ppm to about 400 ppm, about 375 ppm to about 400 ppm, about 400 ppm to about 500 ppm, about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 400 ppm to about 1,100 ppm, about 400 ppm to about 1,200 ppm, about 400 ppm to about 1,300 ppm, about 400 ppm to about 1,400 ppm, about 400 ppm to about 1,500 ppm, about 500 ppm to about 600 ppm, about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about 500 ppm to about 1,000 ppm, about 500 ppm to about
1,100 ppm, about 500 ppm to about 1,200 ppm, about 500 ppm to about 1,300 ppm, about 500 ppm to about
1,400 ppm, about 500 ppm to about 1,500 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 1,000 ppm, about 600 ppm to about 1,100 ppm, about 600 ppm to about 1,200 ppm, about 600 ppm to about 1,300 ppm, about 600 ppm to about 1,400 ppm, about 600 ppm to about 1,500 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 700 ppm to about
1,100 ppm, about 700 ppm to about 1,200 ppm, about 700 ppm to about 1,300 ppm, about 700 ppm to about
1,400 ppm, about 700 ppm to about 1,500 ppm, about 800 ppm to about 900 ppm, about 800 ppm to about 1,000 ppm, about 800 ppm to about 1,100 ppm, about 800 ppm to about 1,200 ppm, about 800 ppm to about 1,300 ppm, about 800 ppm to about 1,400 ppm, about 800 ppm to about 1,500 ppm, about 900 ppm to about 1,000 ppm, about 900 ppm to about 1,100 ppm, about 900 ppm to about 1,200 ppm, about 900 ppm to about 1,300 ppm, about 900 ppm to about 1,400 ppm, about 900 ppm to about 1,500 ppm, about 1,000 ppm to about 1,100 ppm, about 1,000 ppm to about 1,200 ppm, about 1,000 ppm to about 1,300 ppm, about 1,000 ppm to about 1,400 ppm, about 1,000 ppm to about 1,500 ppm, about 1,100 ppm to about 1,200 ppm, about 1,100 ppm to about 1,300 ppm, about 1,100 ppm to about 1,400 ppm, about 1,100 ppm to about 1,500 ppm, about 1,200 ppm to about 1,300 ppm, about 1,200 ppm to about 1,400 ppm, about 1,200 ppm to about 1,500 ppm, about 1,300 ppm to about 1,400 ppm, about 1,300 ppm to about 1,500 ppm or about
1,400 ppm to about 1,500 ppm.
[4]
Composition according to any one of claims 1 to 3, characterized by the fact that the one or more disinfectants are in an amount of about
0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5 %, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0% , about 2.5%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0% or about 10.0% by weight of the composition, or at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1 %, at least
0.25%, at least 0.5%, at least 0.75%, at least 1.0%,
at least 1.5%, at least 2.0%, at least 2.5%, at least
3.0%, at least 4.0%, at least 5.0%, at least 6.0%,
at least 7.0%, at least 7.5%, at least 8.0%, at least
9.0% or at least 10.0% by weight of the composition, or at most
0.01%, maximum 0.05%, maximum 0.075%, maximum 0.1%, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum
1.0%, maximum 1.5%, maximum 2.0%, maximum 2.5%, maximum 3.0%, maximum 4.0%, maximum 5.0%, maximum 6 , 0%,
maximum 7.5%, maximum 8.0%, maximum 9.0% or maximum
10.0% by weight of the composition or about 0.1% to about 0.5%,
about 0.1% to about 0.75%, about 0.1% to about
1.0%, about 0.1% to about 1.5%, about 0.1% to about 2.0%, about 0.1% to about 2.5%, about 0 , 2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1.0%, about 0.2% to about 1, 5%, about 0.2%
about 2.0%, about 0.2% to about 2.5%, about 0.5% to about 1.0%, about 0.5% to about 1.5%, about 0.5% to about 2.0%, about 0.5% to about 2.5%, about 0.5% to about 3.0%, about 0.5% to about 4.0%, about 0.5% to about 5.0%, about 1.0% to about 2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0%, about 1.0% to about 6.0%, about 1.0% to about 7 , 0%, about 1.0% to about 7.5%, about 1.0% to about 8.0%, about 1.0% to about 9.0%, about 1, 0% to about 10.0%, about 2.0% to about 2.5%, about 2.0% to about 3.0%, about 2.0% to about 4.0 %, about 2.0% to about 5.0%, about 2.0% to about 6.0%, about 2.0% to about 7.0%, about 2.0% about 7.5%, about 2.0% to about 8.0%, about 2.0% to about 9.0%, about 2.0% to about 10.0%, about 5.0% to about 6.0%, about 5.0% to about 7.0%, about 5.0% to about 7.5%, about 5.0% around to 8.0%, about 5.0% to about 9.0%, about 5.0% to about 10.0%, about 5.0% to about 11.0%, about from 5.0% to about 12.0%, about 5.0% to about 13.0%, about 5.0% to about 14.0% or about 5.0% to about 15.0% by weight of the composition.
[5]
Composition according to any one of claims 1 to 3, characterized in that the one or more disinfectants are in an amount of about 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm , 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm or 1,000 ppm, or at least 100 ppm, at least least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 pp m, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm or at least
1,000 ppm, or at most 100 ppm, at most 125 ppm, at most 150 ppm, at most 175 ppm, at most 200 ppm, at most 225 ppm, at most 250 ppm, at most 275 ppm, at most 300 ppm, in maximum 325 ppm, maximum 350 ppm, maximum 375 ppm, maximum 400 ppm, maximum 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm, maximum 550 ppm, no maximum 575 ppm, maximum 600 ppm, maximum 625 ppm, maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, maximum 775 ppm, maximum 800 ppm, no maximum 825 ppm, maximum 850 ppm, maximum 875 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm or maximum 1,000 ppm or about 100 ppm at about 200 ppm, approximately from 100 ppm to about 300 ppm, about 100 ppm to about 400 ppm, about 100 ppm to about 500 ppm,
about 100 ppm to about 600 ppm, about 100 ppm to about 700 ppm, about 100 ppm to about 800 ppm, about
100 ppm to about 900 ppm, about 100 ppm to about 1,000 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 400 ppm, about 200 ppm to about 500 ppm,
about 200 ppm to about 600 ppm, about 200 ppm to about 700 ppm, about 200 ppm to about 800 ppm, about
200 ppm to about 900 ppm, about 200 ppm to about 1,000 ppm, about 300 ppm to about 400 ppm, about 300 ppm to about 500 ppm, about 300 ppm to about 600 ppm,
about 300 ppm to about 700 ppm, about 300 ppm to about 800 ppm, about 300 ppm to about 900 ppm, about
300 ppm to about 1,000 ppm, about 400 ppm to about
500 ppm, about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm,
about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 500 ppm to about 600 ppm, about
500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about 500 ppm to about 1,000 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 1,000 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 800 ppm to about 900 ppm, about 800 ppm to about 1,000 ppm or about 900 ppm to about 1,000 ppm.
Composition according to any one of claims 1 to 5, characterized in that the one or more disinfectants include one or more compounds containing a fraction of guanide or functional group, one or more compounds containing aldehyde, one or more organic peroxides, or any combination thereof.
7. Composition according to claim 6, characterized in that the one or more compounds containing guanide comprise, essentially consist of, or consist of a biguanide, a compound containing biguanide, a biguanidine, a compound containing biguanidine, a triguanide , a compound containing triguanide, or any combination thereof.
8. Composition according to claim 7, characterized by the fact that the one or more compounds containing biguanide include a polyhexamethylene biguanide (PHMB), a polyaminopropyl biguanide (PAPB),
a 1,1 '- (1,6-hexanediyl) bis {2- [N' - (2-ethylhexyl) carbamimidoyl] guanidine} (alexidine), a chlorhexidine, a chlorhexidine gluconate or any combination thereof .
Composition according to claim 6, characterized in that the one or more compounds containing aldehyde include one or more aldehydes, one or more dialdehydes, or any combination thereof.
10. Composition according to claim 9, characterized in that the one or more aldehydes include one or more linear aldehydes, one or more branched aldehydes, one or more cyclic aldehydes, one or more aromatic aldehydes, or any combination of the themselves.
11. Composition according to claim 9 or 10, characterized in that the one or more aldehydes include formaldehyde, acetaldehyde, propionaldehyde, butyraldehyde or any combination thereof.
12. Composition according to claim 9, characterized in that the one or more dialdehydes include one or more linear dialdehydes, one or more branched dialdehydes, one or more cyclic dialdehydes, one or more aromatic dialdehydes or any combination thereof .
13. Composition according to claim 9 or 10, characterized in that the one or more dialdehydes include oxaldehyde, malondialdehyde, glutaraldehyde, succinic dialdehyde, phthalaldehyde (ortho-phthalaldehyde), isophthalaldehyde (meta-phthalaldehyde), terephthalaldehyde (for phthalaldehyde) or any combination thereof.
14. Composition according to claim 6, characterized by the fact that the one or more organic peroxides include benzoyl peroxide, ethanoperoxoic acid (peracetic acid) or any combination thereof.
Composition according to any one of claims 6 to 14, characterized in that the one or more compounds containing guanide, the one or more compounds containing aldehyde and / or one or more organic peroxides are in an amount of about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0, 5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0 %, about 2.5%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 6.5%, about 7.0% , about 7.5%, about 8.0%, about 8.5%, about 9.0%, about 9.5%, about 10.0%, about 11%, about 12%, about 13%, about 14%, about 15%, about 20%, about 25% or about 30% by weight of the composition, or at least 0.01%, at least 0.05 %, at least 0.075%, at least 0.1%, at least 0.25%, at least 0.5%, at least 0.75%, at least 1.0%, at least 1.5%, at least least 2.0%, at least 2.5%, at least 3.0%, at least 4.0%, at least 5.0%,
at least 6.0%, at least 7.0%, at least 7.5%, at least
8.0%, at least 9.0%, at least 10.0%, at least 11%,
at least 12%, at least 13%, at least 14%, at least
15%, at least 20%, at least 25% or at least 30% by weight of the composition, or at most 0.01%, at most 0.05%, at most 0.075%, at most 0.1%, in the maximum 0.25%, maximum
0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0%, maximum 2.5%, maximum 3.0%, maximum 4 , 0%,
maximum 5.0%, maximum 6.0%, maximum 7.5%, maximum
8.0%, maximum 9.0%, maximum 10.0%, maximum 11%, maximum 12%, maximum 13%, maximum 14%, maximum 15%, maximum 20%, maximum 25% or maximum 30% by weight of the composition or about 0.1% to about 0.5%, about 0.1%
about 0.75%, about 0.1% to about 1.0%, about
0.1% to about 1.5%, about 0.1% to about 2.0%, about 0.1% to about 2.5%, about 0.1% to about 3 , 0%, about 0.1% to about 3.5%, about 0.1% to about 4.0%, about 0.1% to about 4.5%, about 0, 1% to about 5.0%, about 0.2% to about 0.5%, about 0.2% to about 0.75%,
about 0.2% to about 1.0%, about 0.2% to about 1.5%,
about 0.2% to about 2.0%, about 0.2% to about 2.5%,
about 0.2% to about 3.0%, about 0.2% to about 3.5%,
about 0.2% to about 4.0%, about 0.2% to about 4.5%,
about 0.2% to about 5.0%, about 0.5% to about 1.0%,
about 0.5% to about 1.5%, about 0.5% to about 2.0%,
about 0.5% to about 2.5%, about 0.5% to about 3.0%,
about 0.5% to about 4.0%, about 0.5% to about 5.0%,
about 0.5% to about 6.0%, about 0.5% to about 7.0%,
about 0.5% to about 8.0%, about 0.5% to about 9.0%,
about 0.5% to about 10.0%, about 1.0% to about
2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0%, about 1 , 0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%, about 1.0% to about 8, 0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 1.0% to about 15.0%, about 1.0 % to about 20.0%, about
1.0% to about 25.0%, about 1.0% to about 30.0%, about 2.0% to about 2.5%, about 2.0% to about 3 , 0%, about 2.0% to about 4.0%, about 2.0% to about 5.0%, about 2.0% to about 6.0%, about 2, 0% to about 7.0%, about 2.0% to about 7.5%, about 2.0% to about 8.0%, about 2.0% to about 9.0 %, about 2.0% to about 10.0%,
about 2.0% to about 15.0%, about 2.0% to about
20.0%, about 2.0% to about 25.0%, about 2.0% to about 30.0%, about 5.0% to about 6.0%, about 5 , 0% to about 7.0%, about 5.0% to about 7.5%, about 5.0%
about 8.0%, about 5.0% to about 9.0%, about
5.0% to about 10.0%, about 5.0% to about 11.0%, about 5.0% to about 12.0%, about 5.0% to about 13 , 0%,
about 5.0% to about 14.0%, about 5.0% to about
15.0%, about 5.0% to about 20.0%, about 5.0% to about 25.0%, about 5.0% to about 30.0%, about 6 , 0% to about 7.0%, about 6.0% to about 7.5%, about 6.0%
about 8.0%, about 6.0% to about 9.0%, about
6.0% to about 10.0%, about 6.0% to about 11.0%, about 6.0% to about 12.0%, about 6.0% to about 13 , 0%,
about 6.0% to about 14.0%, about 6.0% to about
15.0%, about 6.0% to about 20.0%, about 6.0% to about 25.0%, about 6.0% to about 30.0%, about 7 , 0% to about 8.0%, about 7.0% to about 9.0%, about 7.0%
about 10.0%, about 7.0% to about 11.0%, about
7.0% to about 12.0%, about 7.0% to about 13.0%, about 7.0% to about 14.0%, about 7.0% to about 15 , 0%,
about 7.0% to about 20.0%, about 7.0% to about
25.0%, about 7.0% to about 30.0%, about 8.0% to about 9.0%, about 8.0% to about 10.0%, about 8 , 0% to about 11.0%, about 8.0% to about 12.0%, about
8.0% to about 13.0%, about 8.0% to about 14.0%, about 8.0% to about 15.0%, about 8.0% to about 20 , 0%,
about 8.0% to about 25.0%, about 8.0% to about
30.0%, about 9.0% to about 10.0%, about 9.0% to about 11.0%, about 9.0% to about 12.0%, about 9 , 0% to about 13.0%, about 9.0% to about 14.0%, about
9.0% to about 15.0%, about 9.0% to about 20.0%, about 9.0% to about 25.0%, about 9.0% to about 30 , 0%,
about 10.0% to about 11.0%, about 10.0% to about 12.0%, about 10.0% to about 13.0%, about 10.0% to about from 14.0%, about 10.0% to about 15.0%, about 10.0% to about 20.0%, about 10.0% to about 25.0%, about 10.0% to about 30.0%, about 15.0% to about 20.0%, about 15.0% to about 25.0%, about 15.0% to about 30 , 0%, about 20.0% to about 25.0%, about 20.0% to about 30.0% or about 20.0% to about 30.0% by weight of the composition.
16. Composition according to any one of claims 6 to 14, characterized in that the one or more aldehydes and / or one or more dialdehydes are in an amount of about 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm or 1,000 ppm , or at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm at least
600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm or at least 1,000 ppm or at most 100 ppm, at most 125 ppm, at most 150 ppm, at most 175 ppm, max 200 ppm, max. 225 ppm, max. 250 ppm, max. 275 ppm, max. 300 ppm, max. 325 ppm, max. 350 ppm, max. 375 ppm, max. 400 ppm, max 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm, maximum 550 ppm, maximum 575 ppm, maximum 600 ppm, maximum 625 ppm, maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, maximum 775 ppm, maximum 800 ppm, maximum 825 ppm, maximum 850 ppm, maximum 875 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm or maximum 1,000 ppm.
17. Composition according to any one of claims 6 to 14, characterized in that the one or more aldehydes and / or one or more dialdehydes are in an amount of about 100 ppm to about 200 ppm, about 100 ppm to about 300 ppm, about 100 ppm to about 400 ppm, about 100 ppm to about 500 ppm, about 100 ppm to about 600 ppm, about 100 ppm to about 700 ppm,
about 100 ppm to about 800 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 1,000 ppm, about
200 ppm to about 300 ppm, about 200 ppm to about 400 ppm, about 200 ppm to about 500 ppm, about 200 ppm to about 600 ppm, about 200 ppm to about 700 ppm,
about 200 ppm to about 800 ppm, about 200 ppm to about 900 ppm, about 200 ppm to about 1,000 ppm, about
300 ppm to about 400 ppm, about 300 ppm to about 500 ppm, about 300 ppm to about 600 ppm, about 300 ppm to about 700 ppm, about 300 ppm to about 800 ppm,
about 300 ppm to about 900 ppm, about 300 ppm to about 1,000 ppm, about 400 ppm to about 500 ppm, about
400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm,
about 500 ppm to about 600 ppm, about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about
500 ppm to about 900 ppm, about 500 ppm to about 1,000 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm,
about 600 ppm to about 1,000 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 800 ppm to about
900 ppm, about 800 ppm to about 1,000 ppm, or about
900 ppm to about 1,000 ppm.
18. Composition according to any one of claims 1 to 17, characterized by the fact that it further comprises, essentially consists of or consists of one or more surfactants that act as foaming agents.
19. Composition characterized by the fact that it comprises, consists essentially of, or consists of available hypochlorous acid or chlorine and one or more surfactants that act as foaming agents.
20. Composition according to claim 19, characterized by the fact that the available free chlorine or hypochlorous acid is in an amount of 0.00005%, 0.00006%, 0.00007%, 0.000075%, 0, 00008%, 0.00009%, 0.0001%, 0.0005%, 0.001%, 0.0015%, 0.002%, 0.0025%, 0.003%, 0.0035%, 0.004%, 0.0045%, 0.005%, 0.0055%, 0.006%, 0.007%, 0.0075%, 0.008%, 0.009%, 0.01%, 0.02%, 0.03%, 0.04% or 0.05% in weight of the composition, or at least 0.00005%, at least 0.00006%, at least 0.00007%, at least 0.000075%, at least 0.00008%, at least 0.00009%, at least 0 , 0001%, at least 0.0005%, at least 0.001%, at least 0.0015%, at least 0.002%, at least 0.0025%, at least 0.003%, at least 0.0035%, at least 0.004 %, at least 0,0045%, at least 0,005%, at least 0,0055%, at least 0,006%, at least 0,007%, at least 0,0075%, at least 0,008%, at least 0,009%, at least 0.01%, at least 0.02%, at least 0.03%,
at least 0.04% or at least 0.05% by weight of the composition,
or at most 0.00005%, at most 0.00006%, at most
0.00007%, maximum 0.000075%, maximum 0.00008%, maximum
0.00009%, maximum 0.0001%, maximum 0.0005%, maximum
0.001%, maximum 0.0015%, maximum 0.002%, maximum
0.0025%, maximum 0.003%, maximum 0.0035%, maximum
0.004%, maximum 0.0045%, maximum 0.005%, maximum
0.0055%, maximum 0.006%, maximum 0.007%, maximum
0.0075%, maximum 0.008%, maximum 0.009%, maximum 0.01%,
maximum 0.02%, maximum 0.03%, maximum 0.04% or maximum 0.05% by weight of the composition or about 0.00075% to about 0.002%, about 0.00075% about 0.003%, about 0.00075% to about 0.004%, about 0.00075% to about
0.005%, about 0.00075% to about 0.006%, about
0.00075% to about 0.007%, about 0.00075% to about
0.008%, about 0.00075% to about 0.009%, about
0.00075% to about 0.01%, about 0.001% to about 0.002%,
about 0.001% to about 0.003%, about 0.001% to about 0.004%, about 0.001% to about 0.005%, about 0.001%
about 0.006%, about 0.001% to about 0.007%, about 0.001% to about 0.008%, about 0.001% to about
0.009%, about 0.001% to about 0.01%, about 0.002% to about 0.003%, about 0.002% to about 0.004%, about
0.002% to about 0.005%, about 0.002% to about 0.006%,
about 0.002% to about 0.007%, about 0.002% to about 0.008%, about 0.002% to about 0.009%, about 0.002% to about 0.01% by weight of the composition
21. Composition according to claim 19, characterized by the fact that the available free chlorine or hypochlorous acid is in an amount of 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0, 25 ppm, 0.30 ppm, 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0, 75 ppm, 0.80 ppm, 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm , 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1,000 ppm, 1,025 ppm, 1,050 ppm, 1,075 ppm, 1,100 ppm, 1,125 ppm, 1,150 ppm, 1,175 ppm, 1,200 ppm, 1,225 ppm,
1,250 ppm, 1,275 ppm, 1,300 ppm, 1,325 ppm, 1,350 ppm, 1,375 ppm, 1,400 ppm, 1,425 ppm, 1,450 ppm, 1,475 ppm or 1,500 ppm, or at least 0.05 ppm, at least 0.10 ppm, at least 0.20 ppm, at least 0.30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least 0.80 ppm, at least 0 , 90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm,
at least 40 ppm, at least 50 ppm, at least 60 ppm, at least 70 ppm, at least 80 ppm, at least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1,000 ppm, at least 1,025 ppm, at least 1,050 ppm, at least 1,075 ppm, at least 1,100 ppm, at least
1,125 ppm, at least 1,150 ppm, at least 1,175 ppm, at least 1,200 ppm, at least 1,225 ppm, at least 1,250 ppm, at least 1,275 ppm, at least 1,300 ppm, at least 1,325 ppm, at least 1,350 ppm, at least 1,375 ppm at least
1,400 ppm, at least 1,425 ppm, at least 1,450 ppm, at least 1,475 ppm or at least 1,500 ppm, or at most 0.05 ppm, at most 0.10 ppm, at most 0.20 ppm, at most 0.30 ppm, maximum 0.40 ppm, maximum 0.50 ppm, maximum 0.60 ppm, maximum 0.70 ppm, maximum 0.80 ppm, maximum 0.90 ppm, maximum 1 ppm, no maximum 10 ppm, maximum 20 ppm, maximum 30 ppm, maximum 40 ppm, maximum 50 ppm, maximum 60 ppm, maximum 70 ppm, maximum 80 ppm, maximum 90 ppm, maximum 100 ppm, no maximum 125 ppm, maximum 150 ppm, maximum 175 ppm, maximum 200 ppm, maximum 225 ppm, maximum 250 ppm, maximum 275 ppm, maximum 300 ppm, maximum 325 ppm, maximum 350 ppm, no maximum 375 ppm, maximum 400 ppm, maximum 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm, maximum 550 ppm, maximum 575 ppm, maximum 600 ppm, no maximum 625 ppm, maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, m maximum 775 ppm, maximum 800 ppm, maximum 825 ppm, maximum 850 ppm, maximum 875 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm, maximum 1,000 ppm maximum 1,025 ppm maximum
1,050 ppm, at most 1,075 ppm, at most 1,100 ppm, at most 1,125 ppm, at most 1,150 ppm, at most 1,175 ppm, at most 1,200 ppm, at most 1,225 ppm, at most 1,250 ppm, at most 1,275 ppm, at most 1,300 ppm maximum
1,325 ppm, at most 1,350 ppm, at most 1,375 ppm, at most 1,400 ppm, at most 1,425 ppm, at most 1,450 ppm, at most 1,475 ppm or at most 1,500 ppm, or about 0.5 ppm at about 20 ppm, about 0.5 ppm to about 25 ppm, about 0.5 ppm to about 30 ppm, about 0.5 ppm to about 35 ppm, about 0.5 ppm to about 40 ppm, about 0.5 ppm to about 45 ppm, about 0.5 ppm to about 50 ppm,
about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 60 ppm, about 0.5 ppm to about 65 ppm, about 0.5 ppm to about 70 ppm, about 0.5 ppm to about 75 ppm,
about 0.5 ppm to about 80 ppm, about 0.5 ppm to about 85 ppm, about 0.5 ppm to about 90 ppm, about 0.5 ppm to about 95 ppm, about 0.5 ppm to about 100 ppm,
about 0.75 ppm to about 20 ppm, about 0.75 ppm to about 25 ppm, about 0.75 ppm to about 30 ppm, about 0.75 ppm to about 35 ppm, about 0.75 ppm at about
40 ppm, about 0.75 ppm to about 45 ppm, about 0.75 ppm to about 50 ppm, about 0.75 ppm to about 55 ppm,
about 0.75 ppm to about 60 ppm, about 0.75 ppm to about 65 ppm, about 0.75 ppm to about 70 ppm, about 0.75 ppm to about 75 ppm, about 0.75 ppm at about
80 ppm, about 0.75 ppm to about 85 ppm, about 0.75 ppm to about 90 ppm, about 0.75 ppm to about 95 ppm,
about 0.75 ppm to about 100 ppm, about 1 ppm to about 20 ppm, about 1 ppm to about 25 ppm, about 1 ppm to about 30 ppm, about 1 ppm to about 35 ppm, about 1 ppm to about 40 ppm, about 1 ppm to about 45 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 55 ppm, about 1 ppm to about 60 ppm, about 1 ppm to about 65 ppm, about 1 ppm to about 70 ppm, about 1 ppm to about 75 ppm, about 1 ppm to about 80 ppm, about 1 ppm to about 85 ppm, about 1 ppm to about 90 ppm, about 1 ppm to about 95 ppm, about 1 ppm to about 100 ppm, about 5 ppm to about 20 ppm, about 5 ppm to about 25 ppm, about 5 ppm to about 30 ppm, about 5 ppm to about 35 ppm, about 5 ppm to about 40 ppm, about 5 ppm to about 45 ppm, about 5 ppm to about 50 ppm, about 5 ppm to about 55 ppm, about 5 ppm to about 60 ppm, about 5 ppm to about 65 ppm, about 5 ppm to about 70 ppm, about 5 ppm to about 75 ppm, about 5 ppm to about 80 ppm, about 5 ppm to about 85 ppm, about 5 ppm to about 90 ppm, about 5 ppm to about 95 ppm, about 5 ppm to about 100 ppm, about 10 ppm to about 20 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 30 ppm, about
10 ppm to about 35 ppm, about 10 ppm to about 40 ppm,
about 10 ppm to about 45 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 55 ppm, about 10 ppm to about 60 ppm, about 10 ppm to about 65 ppm,
about 10 ppm to about 70 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 80 ppm, about 10 ppm to about 85 ppm, about 10 ppm to about 90 ppm,
about 10 ppm to about 95 ppm, or about 10 ppm to about 100 ppm or about 1 ppm to about 25 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 75 ppm ,
about 1 ppm to about 100 ppm, about 1 ppm to about
125 ppm, about 1 ppm to about 150 ppm, about 1 ppm to about 175 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, about 1 ppm to about 250 ppm, about 1 ppm to about 275 ppm, about 1 ppm to about 300 ppm, about 1 ppm to about 325 ppm, about 1 ppm to about 350 ppm, about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about
10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, about 10 ppm to about 125 ppm, about 10 ppm to about 150 ppm, about 10 ppm to about 175 ppm, about 10 ppm to about 200 ppm, about 10 ppm to about 225 ppm, about 10 ppm to about 250 ppm, about 10 ppm to about 275 ppm, about 10 ppm to about 300 ppm, about 10 ppm to about 325 ppm, about 10 ppm to about 350 ppm, about 10 ppm to about 375 ppm, about 10 ppm to about 400 ppm, about 25 ppm to about 50 ppm, about 25 ppm to about 75 ppm, about 25 ppm to about 100 ppm, about 25 ppm to about 125 ppm, about 25 ppm to about 150 ppm, about 25 ppm to about 175 ppm, about 25 ppm to about 200 ppm, about 25 ppm to about 225 ppm, about 25 ppm to about 250 ppm, about 25 ppm to about 275 ppm, about 25 ppm to about 300 ppm, about 25 ppm to about 325 ppm, about 25 ppm to about 350 ppm, about 25 ppm to about 375 ppm, about from 25 ppm to about 400 ppm, about 50 ppm to about 75 ppm, about 50 ppm to about 100 ppm, about 50 ppm to about 125 ppm, about 50 ppm to about 150 ppm, about 50 ppm to about 175 ppm, about 50 ppm to about 200 ppm, about 50 ppm to about 225 ppm, about 50 ppm to about 250 ppm, about 50 ppm to about 275 ppm, about 50 ppm to about 300 ppm, about 50 ppm to about 325 ppm, about 50 ppm to about 350 ppm, about 50 ppm to about 375 ppm, about 50 ppm to about 400 ppm, about 75 ppm to about 100 ppm, about 75 ppm to about 125 ppm, about 75 ppm to about 150 ppm, about 75 ppm to about 175 ppm, about 75 ppm to about 200 ppm, about 75 ppm to about 225 ppm, about 75 ppm to about 250 ppm, about 75 ppm to about 275 ppm, about 75 ppm to about 300 ppm, about 75 ppm to about 325 ppm, about 75 ppm to about 350 ppm, about 75 ppm to about 375 ppm, about 75 ppm to about 400 pp m, about 100 ppm to about
125 ppm, about 100 ppm to about 150 ppm, about 100 ppm to about 175 ppm, about 100 ppm to about 200 ppm,
about 100 ppm to about 225 ppm, about 100 ppm to about 250 ppm, about 100 ppm to about 275 ppm, about
100 ppm to about 300 ppm, about 100 ppm to about 325 ppm, about 100 ppm to about 350 ppm, about 100 ppm to about 375 ppm, about 100 ppm to about 400 ppm,
about 150 ppm to about 175 ppm, about 150 ppm to about 200 ppm, about 150 ppm to about 225 ppm, about
150 ppm to about 250 ppm, about 150 ppm to about 275 ppm, about 150 ppm to about 300 ppm, about 150 ppm to about 325 ppm, about 150 ppm to about 350 ppm,
about 150 ppm to about 375 ppm, about 150 ppm to about 400 ppm, about 200 ppm to about 225 ppm, about
200 ppm to about 250 ppm, about 200 ppm to about 275 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 325 ppm, about 200 ppm to about 350 ppm,
about 200 ppm to about 375 ppm, about 200 ppm to about 400 ppm, about 250 ppm to about 275 ppm, about
250 ppm to about 300 ppm, about 250 ppm to about 325 ppm, about 250 ppm to about 350 ppm, about 250 ppm to about 375 ppm, about 250 ppm to about 400 ppm,
about 300 ppm to about 325 ppm, about 300 ppm to about 350 ppm, about 300 ppm to about 375 ppm, about
300 ppm to about 400 ppm, about 350 ppm to about 375 ppm, about 350 ppm to about 400 ppm, about 375 ppm to about 400 ppm, about 400 ppm to about 500 ppm,
about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about
400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 400 ppm to about 1,100 ppm, about 400 ppm to about 1,200 ppm, about 400 ppm to about 1,300 ppm,
about 400 ppm to about 1,400 ppm, about 400 ppm to about 1,500 ppm, about 500 ppm to about 600 ppm, about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about 500 ppm to about 1,000 ppm, about 500 ppm to about
1,100 ppm, about 500 ppm to about 1,200 ppm, about 500 ppm to about 1,300 ppm, about 500 ppm to about
1,400 ppm, about 500 ppm to about 1,500 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 1,000 ppm, about 600 ppm to about 1,100 ppm, about 600 ppm to about 1,200 ppm, about 600 ppm to about 1,300 ppm, about 600 ppm to about 1,400 ppm, about 600 ppm to about 1,500 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 700 ppm to about
1,100 ppm, about 700 ppm to about 1,200 ppm, about 700 ppm to about 1,300 ppm, about 700 ppm to about
1,400 ppm, about 700 ppm to about 1,500 ppm, about 800 ppm to about 900 ppm, about 800 ppm to about 1,000 ppm, about 800 ppm to about 1,100 ppm, about 800 ppm to about 1,200 ppm, about 800 ppm to about 1,300 ppm, about 800 ppm to about 1,400 ppm, about 800 ppm to about 1,500 ppm, about 900 ppm to about 1,000 ppm, about 900 ppm to about 1,100 ppm, about 900 ppm to about 1,200 ppm, about 900 ppm to about 1,300 ppm, about 900 ppm to about 1,400 ppm, about 900 ppm to about 1,500 ppm, about 1,000 ppm to about 1,100 ppm, about 1,000 ppm to about 1,200 ppm, about 1,000 ppm to about 1,300 ppm, about 1,000 ppm to about 1,400 ppm, about 1,000 ppm to about 1,500 ppm, about 1,100 ppm to about 1,200 ppm, about 1,100 ppm to about 1,300 ppm, about 1,100 ppm to about 1,400 ppm, about 1,100 ppm to about 1,500 ppm, about 1,200 ppm to about 1,300 ppm, about 1,200 ppm to about 1,400 ppm, about 1,200 ppm to about 1,500 ppm, about 1,300 ppm to about 1,400 ppm, about 1,300 ppm to about 1,500 ppm or about
1,400 ppm to about 1,500 ppm.
22. Composition according to any one of claims 18 to 21, characterized in that the one or more surfactants include one or more ionic surfactants, one or more zwitterionic (amphoteric) surfactants, one or more non-ionic surfactants, one or more biotensives or any combination of them
23. Composition according to claim 22, characterized by the fact that the one or more ionic surfactants include one or more anionic surfactants, one or more cationic surfactants or any combination thereof.
24. Composition according to claim 23, characterized in that the one or more anionic surfactants include one or more alkyl sulfates, one or more alkyl ether sulfates, one or more docusates such as sodium dioctyl sulfosuccinates, one or more sulfonate fluorotensive agents, one or more alkyldiphenyloxide, one or more alkyldiphenyloxide disulfonates, one or more potassium phosphate polyether esters, one or more alkyl benzene sulfonates, one or more alkylaryl ether phosphates, one or more ether phosphates alkyl, one or more alkyl carboxylates, one or more carboxylate fluorotensive agents, sodium lauroyl sarcosinate, sodium hexyldiphenyl ether sulfonate (DOWFAX ™ C6L) or any combination thereof.
25. Composition according to claim 24, characterized in that the one or more alkyl sulfates include ammonium lauryl sulfate, sodium lauryl sulfate (SDS) or any combination thereof.
26. Composition according to claim 24, characterized in that the one or more alkyl ether sulfates include sodium lauride sulfate, sodium mireth sulfate or any combination thereof.
27. Composition according to claim 24, characterized in that the one or more docusates include sodium dioctyl sulfosuccinate.
28. Composition according to claim 24, characterized in that the one or more sulfonate fluorotensive agents include perfluorooctane sulfonate (PFOS), perfluorobutane sulfonate or any combination thereof.
29. Composition according to Claim 24, characterized in that the one or more alkyldiphenyloxide disulfonates include DOWFAX ™ 2A1 (disodium phenyl ether lauryl disulfonate), DOWFAX ™ 3B2 (disodium phenyl ether disulfonate), DOWFAX ™ C10L (disodium phenyl ether decyl disulfonate), DOWFAX ™ 2EP, DOWFAX ™ 8390 (disodium phenyl ether cetyl disulfonate) or any combination thereof.
30. Composition according to claim 24, characterized in that the one or more polyether esters of potassium phosphate include TRITON ™ H-55, TRITON ™ H-66 or any combination thereof.
31. Composition according to claim 24, characterized in that the one or more alkyl carboxylates include fatty acid salts, sodium stearate or any combination thereof.
32. Composition according to claim 24, characterized in that the one or more fluorotensive surfactants of carboxylate include perfluorononanoate, perfluoro-octanoate or any combination thereof.
33. Composition according to claim 23, characterized in that the one or more cationic surfactants include one or more quaternary ammonium surfactants, pH-dependent primary amine surfactant, pH-dependent secondary amine surfactant, amine surfactant pH-dependent tertiary or any combination thereof.
34. Composition according to claim 33, characterized by the fact that one or more quaternary ammonium surfactants include benzalkonium chloride (BAC), benzethonium chloride (BZT), benzododecinium bromide (or dimethyldodecylbenzylammonium bromide), bronidox , (or 5-bromo-5-nitro-1,3-dioxane), carbetopendecinium bromide, ketalkonium chloride (CKC), cetrimony, cetrimide, cetylpyridinium chloride (CPC), cetyl trimethylammonium bromide (CTAB or cetrimonium bromide) ) and cetyl trimethylammonium chloride (CTAC or cetrimonium chloride), didecyldimethylammonium chloride (DDAC), dioctadecyldimethylammonium bromide (DODAB or dichloroethylammonium chloride) behenrimium), dofanium chloride, domiphene bromide, methylbenzetonium chloride, octenidine dihydrochloride, polyhydronium chloride, stearalkonium chloride (or dimethylbenzylocta) decylammonium), tetraethylammonium bromide, tetramethylammonium hydroxide (TMAH) and tonzonium bromide, or any combination thereof.
35. Composition according to claim 22, characterized by the fact that one or more zwitterionic surfactants include one or more sultaines, one or more betaines, one or more lecithins, 3 - [(3-colamidopropyl) dimethylammonium] -1 -propanesulfonate (CHAPS) or any combination thereof.
36. Composition according to claim 35, characterized by the fact that the one or more sultaines include cocamidopropyl hydroxysultaine.
37. Composition according to claim 35, characterized by the fact that the one or more betaines include cocamidopropyl betaine.
38. Composition according to claim 22, characterized by the fact that the one or more nonionic surfactants include one or more nonionic polyether surfactants, one or more nonionic polyhydroxyl surfactants or any combination thereof.
39. Composition according to claim 22, characterized in that the one or more non-ionic surfactants include one or more alcohol ethoxylates, one or more alkylphenolic ethoxylates, one or more phenolic ethoxylates, one or more amide ethoxylates, one or more glyceride ethoxylates, one or more fatty acid ethoxylates, one or more grease amine ethoxylates or any combination thereof.
40. Composition according to claim 22,
characterized by the fact that one or more non-ionic surfactants include one or more alkyl esters of polyoxyethylene glycol sorbitan (or ethoxylated sorbital esters),
one or more sorbital esters, one or more polyglycerol esters, one or more ethoxylated polyglycerol esters,
one or more alkyl glycosides, one or more ethoxylated alkyl glycosides, one or more sucrose esters, one or more ethoxylated sucrose esters, one or more amine oxides, one or more ethoxylated alcohols, one or more ethoxylated aliphatic alcohols, one or more alkylamines, one or more ethoxylated alkylamines, one or more ethoxylated alkyl phenols, one or more alkyl polysaccharides, one or more ethoxylated alkyl polysaccharides, one or more ethoxylated fatty acids, one or more ethoxylated fatty alcohols, one or more more ethoxylated fatty amines, one or more poloxamers
(polyethylene-polypropylene copolymers), one or more linear secondary alcohol ethoxylates, one or more alkyl phenyl polyglycolic ethers, one or more polyethylene glycol alkylaryl ethers, one or more polyoxyethylene glycol alkyl ethers, one or more polyethylene glycol ethers , one or more alkylphenolic ethers of polyoxyethylene glycol, one or more phenoxypolyethoxyethanols, one or more alkyl glycoside ethers, one or more alkyl maltoside ethers, one or more alkyl thioglucoside ethers, one or more digitonins, one or more glycol esters , one or more alkylaryl polyether sulfates, one or more alcohol sulfonates, one or more alkyl sorbitan esters, one or more glycerol alkyl esters, one or more cocamide ethanolamines, sucrose monolaurate, dodecyldimethylamine oxide, sodium cholate , 2-dodecoxyethanol (LUBROL®-PX) or any combination thereof.
41. Composition according to claim 40, characterized in that the one or more alkyl esters of polyoxyethylene glycol (or ethoxylated sorbital esters) include polysorbate 20 sorbitan monooleate (TWEEN® 20), mono- polysorbate 40 sorbitan oleate (TWEEN® 40), polysorbate 60 sorbitan mono-oleate (TWEEN® 60), polysorbate 61 sorbitan mono-oleate (TWEEN® 61), polysorbate 65 sorbitan mono-oleate (TWEEN® ® 65), polysorbate 80 sorbitan monooleate (TWEEN® 80), polysorbate 81 sorbitan monooleate (TWEEN® 81), polysorbate 85 sorbitan monooleate (TWEEN® 85) or any combination thereof .
42. Composition according to claim 40, characterized in that the one or more sorbital esters include sorbitan mono-oleate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan tristearate or any combination thereof .
43. Composition according to claim 40, characterized in that the one or more polyglycerol esters include glycerol mono-oleate, glycerol monolaurate, glycerol monopalmitate, glycerol monostearate, glycerol trioleate, glycerol ricinoleate, glycerol tristearate or any combination thereof.
44. Composition according to claim 40, characterized in that the one or more alkyl glycosides include arachidyl glycoside, C12-20 alkyl glycoside, caprylil / capryl glycoside, cetearyl glycoside, coco-glycoside, glycoside of ethyl and lauryl glycoside, decyl glycoside or any combination thereof.
45. Composition according to claim 40, characterized in that the one or more sucrose esters include sucrose mono-oleate, sucrose monolaurate, sucrose monopalmitate, sucrose monostearate, sucrose trioleate, sucrose ricinoleate, sucrose tristearate, sucrose diglycerides, sucrose triacetate or any combination thereof.
46. Composition according to claim 40, characterized in that the one or more ethoxylated alkyl phenols include ethoxylated nonyl-phenol, ethoxylated octyl-phenol or any combination thereof.
47. Composition according to claim 40, characterized in that the one or more ethoxylated fatty acids include ethoxylated castor oil.
48. Composition according to claim 40, characterized in that the one or more ethoxylated fatty alcohols include ethoxylated keto-oleyl alcohol, ethoxylated keto-stearyl alcohol, ethoxylated decyl alcohol, ethoxylated dodecyl alcohol, or any combination of ethoxylates of the same.
49. Composition according to claim 40, characterized in that the one or more poloxamers (polyethylene-polypropylene copolymers) include Poloxamer 124 (PLURONIC® L44), Poloxamer 181 (PLURONIC® L61), Poloxamer 182 (PLURONIC® L62), Poloxamer 184 (PLURONIC® L64), Poloxamer 188 (PLURONIC® F68), Poloxamer 237 (PLURONIC® F87), Poloxamer 338 (PLURONIC® L108), Poloxamer 407 (PLURONIC® F127) or any combination thereof.
50. Composition according to claim 40, characterized in that the one or more linear secondary alcohol ethoxylates include TERGITOL ™ 15-S-5, TERGITOL ™ 15-S-7, TERGITOL ™ 15-S-9, TERGITOL ™ 15-S-12, TERGITOL ™ 15-S-15, TERGITOL ™ 15-S-20, TERGITOL ™ 15-S-30,
TERGITOL ™ 15-S-40 or any combination thereof.
51. Composition according to claim 40, characterized in that the one or more alkyl polyoxyethylene glycol ethers include octaethylene glycol monododecyl ether, pentaethylene glycol monododecyl ether, BRIJ® 30, BRIJ® 35 or any combination thereof.
52. Composition according to claim 40, characterized in that the one or more polyoxyethylene glycol octylphenol ethers include polyoxyethylene ether (4-5) p-t-octyl phenol (TRITON® X-45), octylphenyl ether of polyoxyethylene (TRITON® X-100) or any combination thereof.
53. Composition according to claim 40, characterized in that the one or more alkylphenolic ethers of polyoxyethylene glycol include Nonoxynol-
9.
54. Composition according to claim 40, characterized in that the one or more phenoxypolyethoxyethanols include nonylphenoxypolyethoxyethanol, octylphenoxypolyethoxyethanol (IGEPAL® CA-630 or NONIDET ™ P-40) or any combination thereof.
55. Composition according to claim 40, characterized in that the one or more alkyl glycoside ethers include octyl glycopyranoside.
56. Composition according to claim 40, characterized in that the one or more alkyl maltoside ethers include dodecyl maltopyranide.
57. Composition according to claim 40, characterized in that the one or more alkyl thioglucoside ethers include heptyl thioglycopyranoside.
58. Composition according to claim 40, characterized in that the one or more alkyl esters of glycerol include glyceryl laurate.
59. Composition according to claim 40, characterized in that the one or more cocamide ethanolamines include cocamide monoethanolamine, cocamide diethanolamine or any combination thereof.
60. Composition according to claim 22, characterized by the fact that one or more bio-surfactants include one or more bio-based anionic surfactants, one or more non-ionic bio-based surfactants or any combination thereof.
61. Composition according to claim 60, characterized by the fact that one or more anionic bio-based surfactants include STEPONOL® AM 30-KE, an ammonium lauryl sulfate, and STEPONOL® EHS, a 2-ethyl hexyl sulfate sodium, or any combination thereof.
62. Composition according to claim 60, characterized by the fact that one or more bio-based non-ionic surfactants include STEPOSOL® MET-10U, a metathesis-derived non-ionic surfactant which is a short-chain unsaturated amide.
63. Composition according to any one of claims 18 to 62, characterized by the fact that the one or more surfactants are in a number of aspects, for example, about 0.001%, about 0.005%, about 0, 0075%, about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about about 2.0%, about 2.5%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0% or about 10.0% by weight of the composition, or at least 0.001%, at least 0.005%, at least 0.0075%, at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1%, at least 0.25%, at least 0.5%, at least 0.75%, at least 1.0 %, at least 1.5%, at least 2.0%, at least 2.5%, at least 3.0%, at least 4.0%, at least 5.0%, at least 6.0% at least 7.0%, at least 7.5%, at least at 8.0%, at least 9.0% or at least 10.0% by weight of the composition, or at most 0.001%, at most 0.005%, at most 0.0075%, at most 0.01%, at maximum 0.05%, maximum
0.075%, maximum 0.1%, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0 %,
maximum 2.5%, maximum 3.0%, maximum 4.0%, maximum
5.0%, at most 6.0%, at most 7.5%, at most 8.0%, at most 9.0% or at most 10.0% by weight of the composition or about 0.001% at about 0.005%, about 0.001% to about
0.0075%, about 0.001% to about 0.01%, about 0.001%
about 0.025%, about 0.001% to about 0.05%, about 0.001% to about 0.075%, about 0.001% to about 0.1%,
about 0.001% to about 0.25%, about 0.001% to about
0.75%, about 0.001% to about 1.0%, about 0.005% to about 0.0075%, about 0.005% to about 0.01%, about
0.005% to about 0.025%, about 0.005% to about 0.05%,
about 0.005% to about 0.075%, about 0.005% to about 0.1%, about 0.005% to about 0.25%, about 0.005%
about 0.75%, about 0.005% to about 1.0%, about
0.01% to about 0.05%, about 0.01% to about 0.075%,
about 0.01% to about 0.1%, about 0.01% to about
0.25%, about 0.01% to about 0.5%, about 0.01% to about 0.75%, about 0.01% to about 1.0%, about 0 , 01% to about 1.5%, about 0.01% to about 2.0%, about 0.01%
about 2.5%, about 0.05% to about 0.075%, about
0.05% to about 0.1%, about 0.05% to about 0.25%, about 0.05% to about 0.5%, about 0.05% to about 0 , 75%,
about 0.05% to about 1.0%, about 0.05% to about
1.5%, about 0.05% to about 2.0%, about 0.05% to about 2.5%, about 0.1% to about 0.5%, about 0 , 1% to about 0.75%, about 0.1% to about 1.0%, about 0.1% to about 1.5%, about 0.1% to about 2, 0%, about 0.1%
about 2.5%, about 0.1% to about 3.0%, about
0.1% to about 4.0%, about 0.1% to about 5.0%, about 0.2% to about 0.5%, about 0.2% to about 0 , 75%,
about 0.2% to about 1.0%, about 0.2% to about 1.5%,
about 0.2% to about 2.0%, about 0.2% to about 2.5%,
about 0.2% to about 3.0%, about 0.2% to about 4.0%,
about 0.2% to about 5.0%, about 0.5% to about 1.0%,
about 0.5% to about 1.5%, about 0.5% to about 2.0%,
about 0.5% to about 2.5%, about 0.5% to about 3.0%,
about 0.5% to about 4.0%, about 0.5% to about 5.0%,
about 0.5% to about 6.0%, about 0.5% to about 7.0%,
about 0.5% to about 8.0%, about 0.5% to about 9.0%,
about 0.5% to about 10.0%, about 1.0% to about
2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0%, about 1 , 0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%, about 1.0% to about 8, 0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 2.0% to about 2.5%, about 2.0 % to about 3.0%, about 2.0%
about 4.0%, about 2.0% to about 5.0%, about
2.0% to about 6.0%, about 2.0% to about 7.0%, about 2.0% to about 7.5%, about 2.0% to about 8 , 0%, about 2.0% to about 9.0%, about 2.0% to about 10.0%, about 5.0% to about 6.0%, about 5, 0% to about 7.0%, about 5.0% to about 7.5%, about 5.0% to about 8.0%, about 5.0% to about 9.0 %, about 5.0% to about 10.0%, about 5.0% to about 11.0%, about 5.0% to about 12.0%, about 5.0% about 13.0%, about 5.0% to about 14.0%, about 5.0% to about 15.0%, about 6.0% to about 7.0%, about 6.0% to about 7.5%, about 6.0% to about 8.0%, about 6.0% to about 9.0%, about 6.0% to about from 10.0%, about 6.0% to about 11.0%, about 6.0% to about 12.0%, about 6.0% to about 13.0%, about 6.0% to about 14.0% or about 6.0% to about 15.0% by weight of the composition.
63. Composition characterized by the fact that it comprises, consists essentially of, or consists of one or more compounds containing guanide and one or more alcohols.
64. Composition according to claim 63, characterized in that the one or more compounds containing guanide comprise, essentially consist of or consist of a biguanide, a compound containing biguanide, a biguanidine, a compound containing biguanidine, a triguanide, a compound containing triguanide or any combination thereof.
65. Composition according to claim 64, characterized in that the one or more compounds containing biguanide include a polyhexamethylene biguanide (PHMB), a polyaminopropyl biguanide (PAPB), a 1.1 '- (1, 6-hexanediyl) bis {2- [N '- (2-ethylhexyl) carbamimidoyl] guanidine} (alexidine), a chlorhexidine, a chlorhexidine gluconate or any combination thereof.
66. Composition according to any one of claims 63 to 65, characterized in that the one or more alcohols are methanol, ethanol, propanol, isopropanol, butanol, pentanol and 1-hexadecanol.
67. Composition according to any one of claims 63 to 66, characterized in that the one or more compounds containing guanide are in an amount of about 0.01%, about 0.05%, about 0.075% , about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 6.5%, about 7.0%, about 7.5%, about 8.0%, about 8.5%, about 9.0%, about 9.5%, about 10.0%. about 11%, about 12%, about 13%, about 14%, about 15%, about 20%, about 25% or about 30% by weight of the composition, or at least 0.01 %, at least
0.05%, at least 0.075%, at least 0.1%, at least 0.25%,
at least 0.5%, at least 0.75%, at least 1.0%, at least 1.5%, at least 2.0%, at least 2.5%, at least
3.0%, at least 4.0%, at least 5.0%, at least 6.0%,
at least 7.0%, at least 7.5%, at least 8.0%, at least
9.0%, at least 10.0%, at least 11%, at least 12%, at least 13%, at least 14%, at least 15%, at least 20%,
at least 25% or at least 30% by weight of the composition, or at most 0.01%, at most 0.05%, at most 0.075%, at most
0.1%, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0%, maximum 2 , 5%,
maximum 3.0%, maximum 4.0%, maximum 5.0%, maximum
6.0%, at most 7.5%, at most 8.0%, at most 9.0%, at most 10.0%, at most 11%, at most 12%, at most 13%,
maximum 14%, maximum 15%, maximum 20%, maximum 25%
or at most 30% by weight of the composition or about 0.1% to about 0.5%, about 0.1% to about 0.75%, about 0.1%
about 1.0%, about 0.1% to about 1.5%, about
0.1% to about 2.0%, about 0.1% to about 2.5%, about 0.1% to about 3.0%, about 0.1% to about 3 , 5%, about 0.1% to about 4.0%, about 0.1% to about 4.5%, about 0.1% to about 5.0%, about 0, 2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1.0%,
about 0.2% to about 1.5%, about 0.2% to about 2.0%,
about 0.2% to about 2.5%, about 0.2% to about 3.0%,
about 0.2% to about 3.5%, about 0.2% to about 4.0%,
about 0.2% to about 4.5%, about 0.2% to about 5.0%,
about 0.5% to about 1.0%, about 0.5% to about 1.5%,
about 0.5% to about 2.0%, about 0.5% to about 2.5%,
about 0.5% to about 3.0%, about 0.5% to about 4.0%,
about 0.5% to about 5.0%, about 0.5% to about 6.0%,
about 0.5% to about 7.0%, about 0.5% to about 8.0%,
about 0.5% to about 9.0%, about 0.5% to about
10.0%, about 1.0% to about 2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1 , 0% to about 5.0%, about 1.0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7, 5%, about 1.0% to about 8.0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 1.0 % to about 15.0%, about 1.0% to about 20.0%, about 1.0% to about 25.0%, about
1.0% to about 30.0%, about 2.0% to about 2.5%, about 2.0% to about 3.0%, about 2.0% to about 4 , 0%, about 2.0% to about 5.0%, about 2.0% to about 6.0%, about 2.0% to about 7.0%, about 2, 0% to about 7.5%, about 2.0% to about 8.0%, about 2.0% to about 9.0%, about 2.0% to about 10.0 %, about 2.0% to about 15.0%,
about 2.0% to about 20.0%, about 2.0% to about
25.0%, about 2.0% to about 30.0%, about 5.0% to about 6.0%, about 5.0% to about 7.0%, about 5 , 0% to about 7.5%, about 5.0% to about 8.0%, about 5.0% to about 9.0%, about 5.0% to about 10, 0%, about 5.0% to about 11.0%, about 5.0% to about 12.0%, about
5.0% to about 13.0%, about 5.0% to about 14.0%, about 5.0% to about 15.0%, about 5.0% to about 20 , 0%,
about 5.0% to about 25.0%, about 5.0% to about
30.0%, about 6.0% to about 7.0%, about 6.0% to about 7.5%, about 6.0% to about 8.0%, about 6 , 0% to about 9.0%, about 6.0% to about 10.0%, about 6.0% to about 11.0%, about 6.0% to about 12, 0%, about
6.0% to about 13.0%, about 6.0% to about 14.0%, about 6.0% to about 15.0%, about 6.0% to about 20 , 0%,
about 6.0% to about 25.0%, about 6.0% to about
30.0%, about 7.0% to about 8.0%, about 7.0% to about 9.0%, about 7.0% to about 10.0%, about 7 , 0% to about 11.0%, about 7.0% to about 12.0%, about
7.0% to about 13.0%, about 7.0% to about 14.0%, about 7.0% to about 15.0%, about 7.0% to about 20 , 0%,
about 7.0% to about 25.0%, about 7.0% to about
30.0%, about 8.0% to about 9.0%, about 8.0% to about 10.0%, about 8.0% to about 11.0%, about 8 , 0% to about 12.0%, about 8.0% to about 13.0%, about
8.0% to about 14.0%, about 8.0% to about 15.0%, about 8.0% to about 20.0%, about 8.0% to about 25 , 0%,
about 8.0% to about 30.0%, about 9.0% to about
10.0%, about 9.0% to about 11.0%, about 9.0% to about 12.0%, about 9.0% to about 13.0%, about 9 , 0% to about 14.0%, about 9.0% to about 15.0%, about 9.0% to about 20.0%, about 9.0% to about 25, 0%, about 9.0% to about 30.0%, about 10.0% to about 11.0%, about 10.0% to about 12.0%, about 10.0 % to about 13.0%, about 10.0% to about 14.0%, about 10.0% to about 15.0%, about 10.0% to about 20.0% , about 10.0% to about 25.0%, about 10.0% to about 30.0%, about 15.0% to about 20.0%, about 15.0% to about 25.0%, about 15.0% to about 30.0%, about 20.0% to about 25.0%, about 20.0% to about 30.0% or about from 20.0% to about 30.0% by weight of the composition.
68. Composition according to any one of claims 63 to 67, characterized in that the one or more alcohols are in an amount of about 5%, about 10%, about 15%, about 20%, about 25%, about 30%, about 35%, about 40%, about 45%, about 50%, about 55%, about 60%, about 65%, about 70%, about 75%, about 80%, about 85%, about 90%, about 95%, about 96%, about 97%, about 98% or about 99% by weight of the composition, or at least 5%, at least 10%, at least 15%, at least 20%, at least 25%, at least 30%, at least 35%, at least 40%, at least 45%, at least 50%, at least 55%, at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least
85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or at least 99% by weight of the composition, or at most 5%, at most 10%, at most 15%,
maximum 20%, maximum 25%, maximum 30%, maximum 35%,
maximum 40%, maximum 45%, maximum 50%, maximum 55%,
maximum 60%, maximum 65%, maximum 70%, maximum 75%,
maximum 80%, maximum 85%, maximum 90%, maximum 95%,
maximum 96%, maximum 97%, maximum 98% or maximum 99%
by weight of the composition or about 5% to about 10%, about 5% to about 20%, about 5% to about 30%, about
5% to about 40%, about 5% to about 50%, about 5%
about 60%, about 5% to about 70%, about 5% to about 80%, about 5% to about 90%, about 5% to about 95%, about 5% about 97%, about 5% to about
99%, about 10% to about 20%, about 10% to about
30%, about 10% to about 40%, about 10% to about
50%, about 10% to about 60%, about 10% to about
70%, about 10% to about 80%, about 10% to about
90%, about 10% to about 95%, about 10% to about
97%, about 10% to about 99%, about 20% to about
30%, about 20% to about 40%, about 20% to about
50%, about 20% to about 60%, about 20% to about
70%, about 20% to about 80%, about 20% to about
90%, about 20% to about 95%, about 20% to about
97%, about 20% to about 99%, about 30% to about
40%, about 30% to about 50%, about 30% to about
60%, about 30% to about 70%, about 30% to about
80%, about 30% to about 90%, about 30% to about
95%, about 30% to about 97%, about 30% to about
99%, about 35% to about 40%, about 35% to about
50%, about 35% to about 60%, about 35% to about
70%, about 35% to about 80%, about 35% to about
90%, about 35% to about 95%, about 35% to about
97%, about 35% to about 99%, about 40% to about
50%, about 40% to about 60%, about 40% to about
70%, about 40% to about 80%, about 40% to about
90%, about 40% to about 95%, about 40% to about
97%, about 40% to about 99%, about 45% to about
50%, about 45% to about 60%, about 45% to about
70%, about 45% to about 80%, about 45% to about
90%, about 45% to about 95%, about 45% to about
97%, about 45% to about 99%, about 50% to about
60%, about 50% to about 70%, about 50% to about
80%, about 50% to about 90%, about 50% to about
95%, about 50% to about 97%, about 50% to about
99%, about 60% to about 70%, about 60% to about
80%, about 60% to about 90%, about 60% to about
95%, about 60% to about 97%, about 60% to about
99%, about 70% to about 80%, about 70% to about
90%, about 70% to about 95%, about 70% to about
97%, about 70% to about 99%, about 80% to about 90%, about 80% to about 95%, about 80% to about 97%, about 80% to about 99%, about 90% to about 95%, about 90% to about 97%, about 90% to about 99% by weight of the composition.
69. Composition characterized by the fact that it comprises, consists essentially of, or consists of one or more compounds containing guanide.
70. Composition according to claim 69, characterized in that the one or more compounds containing guanide comprise, consist essentially of or consist of a biguanide, a compound containing biguanide, a biguanidine, a compound containing biguanidine, a triguanide, a compound containing triguanide or any combination thereof.
71. Composition according to claim 70, characterized by the fact that the one or more compounds containing biguanide include a polyhexamethylene biguanide (PHMB), a polyaminopropyl biguanide (PAPB), a 1.1 '- (1, 6-hexanediyl) bis {2- [N '- (2-ethylhexyl) carbamimidoyl] guanidine} (alexidine), a chlorhexidine, a chlorhexidine gluconate or any combination thereof.
72. Composition according to any one of claims 69 to 71, characterized in that the one or more alcohols are methanol, ethanol, propanol, isopropanol, butanol, pentanol and 1-hexadecanol.
73. Composition according to any one of claims 69 to 72, characterized in that the one or more compounds containing guanide are in an amount of about 0.01%, about 0.05%, about 0.075% , about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 6.5%, about 7.0%, about 7.5%, about 8.0%, about 8.5%, about 9.0%, about 9.5%, about 10.0%. about 11%, about 12%, about 13%, about 14%, about 15%, about 20%, about 25% or about 30% by weight of the composition, or at least 0.01 %, at least 0.05%, at least 0.075%, at least 0.1%, at least 0.25%, at least 0.5%, at least 0.75%, at least 1.0%, at least least 1.5%, at least 2.0%, at least 2.5%, at least 3.0%, at least 4.0%, at least 5.0%, at least 6.0%, at least 7.0%, at least 7.5%, at least 8.0%, at least 9.0%, at least 10.0%, at least 11%, at least 12%, at least 13%, at least 14%, at least 15%, at least 20%, at least 25% or at least 30% by weight of the composition, or at most 0.01%, at most 0.05%, at most 0.075%, at most 0 , 1%, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0%, maximum 2, 5%,
maximum 3.0%, maximum 4.0%, maximum 5.0%, maximum
6.0%, at most 7.5%, at most 8.0%, at most 9.0%, at most 10.0%, at most 11%, at most 12%, at most 13%,
maximum 14%, maximum 15%, maximum 20%, maximum 25%
or at most 30% by weight of the composition or about 0.1% to about 0.5%, about 0.1% to about 0.75%, about 0.1%
about 1.0%, about 0.1% to about 1.5%, about
0.1% to about 2.0%, about 0.1% to about 2.5%, about 0.1% to about 3.0%, about 0.1% to about 3 , 5%, about 0.1% to about 4.0%, about 0.1% to about 4.5%, about 0.1% to about 5.0%, about 0, 2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1.0%,
about 0.2% to about 1.5%, about 0.2% to about 2.0%,
about 0.2% to about 2.5%, about 0.2% to about 3.0%,
about 0.2% to about 3.5%, about 0.2% to about 4.0%,
about 0.2% to about 4.5%, about 0.2% to about 5.0%,
about 0.5% to about 1.0%, about 0.5% to about 1.5%,
about 0.5% to about 2.0%, about 0.5% to about 2.5%,
about 0.5% to about 3.0%, about 0.5% to about 4.0%,
about 0.5% to about 5.0%, about 0.5% to about 6.0%,
about 0.5% to about 7.0%, about 0.5% to about 8.0%,
about 0.5% to about 9.0%, about 0.5% to about
10.0%, about 1.0% to about 2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1 , 0% to about 5.0%, about 1.0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7, 5%, about 1.0% to about 8.0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 1.0 % to about 15.0%, about 1.0% to about 20.0%, about 1.0% to about 25.0%, about
1.0% to about 30.0%, about 2.0% to about 2.5%, about 2.0% to about 3.0%, about 2.0% to about 4 , 0%, about 2.0% to about 5.0%, about 2.0% to about 6.0%, about 2.0% to about 7.0%, about 2, 0% to about 7.5%, about 2.0% to about 8.0%, about 2.0% to about 9.0%, about 2.0% to about 10.0 %, about 2.0% to about 15.0%,
about 2.0% to about 20.0%, about 2.0% to about
25.0%, about 2.0% to about 30.0%, about 5.0% to about 6.0%, about 5.0% to about 7.0%, about 5 , 0% to about 7.5%, about 5.0% to about 8.0%, about 5.0% to about 9.0%, about 5.0% to about 10, 0%, about 5.0% to about 11.0%, about 5.0% to about 12.0%, about
5.0% to about 13.0%, about 5.0% to about 14.0%, about 5.0% to about 15.0%, about 5.0% to about 20 , 0%,
about 5.0% to about 25.0%, about 5.0% to about
30.0%, about 6.0% to about 7.0%, about 6.0% to about 7.5%, about 6.0% to about 8.0%, about 6 , 0% to about 9.0%, about 6.0% to about 10.0%, about 6.0% to about 11.0%, about 6.0% to about 12, 0%, about
6.0% to about 13.0%, about 6.0% to about 14.0%, about 6.0% to about 15.0%, about 6.0% to about 20 , 0%,
about 6.0% to about 25.0%, about 6.0% to about
30.0%, about 7.0% to about 8.0%, about 7.0% to about 9.0%, about 7.0% to about 10.0%, about 7 , 0% to about 11.0%, about 7.0% to about 12.0%, about
7.0% to about 13.0%, about 7.0% to about 14.0%, about 7.0% to about 15.0%, about 7.0% to about 20 , 0%,
about 7.0% to about 25.0%, about 7.0% to about
30.0%, about 8.0% to about 9.0%, about 8.0% to about 10.0%, about 8.0% to about 11.0%, about 8 , 0% to about 12.0%, about 8.0% to about 13.0%, about
8.0% to about 14.0%, about 8.0% to about 15.0%, about 8.0% to about 20.0%, about 8.0% to about 25 , 0%,
about 8.0% to about 30.0%, about 9.0% to about
10.0%, about 9.0% to about 11.0%, about 9.0% to about 12.0%, about 9.0% to about 13.0%, about 9 , 0% to about 14.0%, about 9.0% to about 15.0%, about
9.0% to about 20.0%, about 9.0% to about 25.0%, about 9.0% to about 30.0%, about 10.0% to about 11 , 0%,
about 10.0% to about 12.0%, about 10.0% to about
13.0%, about 10.0% to about 14.0%, about 10.0% to about 15.0%, about 10.0% to about 20.0%, about
10.0% to about 25.0%, about 10.0% to about 30.0%,
about 15.0% to about 20.0%, about 15.0% to about
25.0%, about 15.0% to about 30.0%, about 20.0% to about 25.0%, about 20.0% to about 30.0% or about 20 , 0% to about 30.0% by weight of the composition.
74. Composition according to any one of claims 1 to 73, characterized in that it additionally comprises, essentially consists of or consists of one or more carriers.
75. Composition according to claim 74, characterized in that the one or more carriers include an aqueous carrier, a semi-solid carrier, a solid carrier or any combination thereof.
76. Composition according to claim 74 or 75, characterized in that the one or more carriers include water, a vegetable oil, a mineral oil, an ester oil, an ether, one or more alcohols, a fatty alcohol , an isoparaffin, a hydrocarbon oil, a polyol, a wax or any combination thereof.
77. Composition according to claim 76, characterized in that the ester oil includes octal palmitate, isopropyl myristate or isopropyl palmitate.
78. Composition according to claim 76, characterized by the fact that the ether includes tippryl ether or isosorbide dimethyl.
79. Composition according to claim 76, characterized by the fact that the alcohol includes ethanol or isopropanol.
80. Composition according to claim 76, characterized by the fact that fatty alcohol includes cetyl alcohol, cetearyl alcohol, stearyl alcohol or beenyl alcohol.
81. Composition according to claim 76, characterized by the fact that isoparaffin includes isooctane, isododecane (IDD) or isohexadecane.
82. Composition according to claim 76, characterized in that the hydrocarbon oil includes mineral oil, petrolatum, isoeicosane or a polyolefin.
83. Composition according to claim 76, characterized by the fact that the polyol includes propylene glycol, glycerin, butylene glycol, pentylene glycol, hexylene glycol or caprylyl glycol.
84. Composition according to claim 76, characterized in that the wax includes beeswax, carnauba, ozocerite, microcrystalline wax, polyethylene wax or a botanical wax.
85. Composition according to any one of claims 74 to 84, characterized by the fact that the one or more carriers are in an amount of at least 25%, at least 30%, at least 35%, at least 40%, at least 45%, at least 50%, at least 55%, at least 60%,
at least 65%, at least 70%, at least 75%, at least
80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or at least 99%
by weight of the composition, or a maximum of 25%, a maximum of 30%, a maximum of 35%, a maximum of 40%, a maximum of 45%, a maximum of 50%, a maximum of 55%, a maximum of 60%, a maximum of 65% maximum 70%, maximum 75%, maximum 80%, maximum 85%, maximum 90%, maximum 95%, maximum 96%, maximum 97%, maximum 98% or maximum 99% by weight of the composition or about 25% to about 50%, about 25% to about 75%, about 25% to about
90%, about 25% to about 95%, about 25% to about
96%, about 25% to about 97%, about 25% to about
98%, about 25% to about 99%, about 50% to about
75%, about 50% to about 90%, about 50% to about
95%, about 50% to about 96%, about 50% to about
97%, about 50% to about 98%, about 50% to about
99%, about 75% to about 80%, about 75% to about
85%, about 75% to about 90%, about 75% to about
95%, about 75% to about 96%, about 75% to about
97%, about 75% to about 98%, about 75% to about
99%, about 80% to about 85%, about 80% to about
90%, about 80% to about 95%, about 80% to about
96%, about 80% to about 97%, about 80% to about
98%, about 80% to about 99%, about 85% to about
90%, about 85% to about 95%, about 85% to about
96%, about 85% to about 97%, about 85% to about 98%, about 85% to about 99%, about 90% to about 95%, about 90% to about 96%, about 90% to about 97%, about 90% to about 98%, about 90% to about 99% or about 95% to about 99% by weight of the composition.
86. Composition according to any one of claims 1 to 85, characterized in that it additionally comprises, essentially consists of or consists of one or more additional ingredients.
87. Composition according to claim 86, characterized in that the one or more additional ingredients include a preservative, a chelating agent or any combination thereof.
88. Composition according to any one of claims 1 to 87, characterized in that it has a pH of about 2 to about 5, about 2 to about 5.5, about 2 to about 6, about 2 to about 6.5, about 2 to about 7, about 2 to about 7.5, about 2 to about 8, about 2 to about 8.5, about 2 to about 9, about 2.5 to about 5, about 2.5 to about 5.5, about 2.5 to about 6, about 2.5 to about 6.5, about 2.5 to about 7, about 2.5 to about 7.5, about 2.5 to about 8, about 2.5 to about 8.5, about 2.5 to about 9, about 3 to about 5, about 3 to about 5.5, about 3 to about 6, about 3 to about 6.5,
about 3 to about 7, about 3 to about 7.5, about
3 to about 8, about 3 to about 8.5, about 3 to about 9, about 3.5 to about 5, about 3.5 to about
5.5, about 3.5 to about 6, about 3.5 to about 6.5,
about 3.5 to about 7, about 3.5 to about 7.5, about 3.5 to about 8, about 3.5 to about 8.5, about
3.5 to about 9, about 4 to about 5, about 4 to about 5.5, about 4 to about 6, about 4 to about 6.5,
about 4 to about 7, about 4 to about 7.5, about
4 to about 8, about 4 to about 8.5, about 4 to about 9, about 4.5 to about 5, about 4.5 to about
5.5, about 4.5 to about 6, about 4.5 to about 6.5,
about 4.5 to about 7, about 4.5 to about 7.5, about 4.5 to about 8, about 4.5 to about 8.5, about
4.5 to about 9, about 5 to about 5.5, about 5 to about 6, about 5 to about 6.5, about 5 to about
7, about 5 to about 7.5, about 5 to about 8, about 5 to about 8.5, about 5 to about 9, about 5.5 to about 6, about 5.5 to about 6.5, about 5.5 to about 7, about 5.5 to about 7.5, about 5.5 to about 8, about 5.5 to about 8.5, about 5.5 to about
9, about 6 to about 6.5, about 6 to about 7, about 6 to about 7.5, about 6 to about 8, about 6 to about 8.5, about 6 to about 9, about 6.5 to about 7, about 6.5 to about 7.5, about 6.5 to about
8, about 6.5 to about 8.5, about 6.5 to about 9, about 7 to about 7.5, about 7 to about 8, about 7 to about 8, 5, about 7 to about 9, about 7.5 to about 8, about 7.5 to about 8.5, about 7.5 to about 9, about 8 to about 8, 5, about 8 to about 9 or about 8.5 to about 9.
89. Composition according to any one of claims 1 to 87, characterized in that it has a pH of about 6 to about 8, about 6.7 to about 7.7, about 6.8 to about 7.6, about 6.9 to about 7.5, about 7.0 to about 7.4, about 7.1 to about 7.3 or about 7.2.
90. Composition according to any one of claims 1 to 87, characterized in that it has a pH of about 5.0 to about 6.5, about 5.2 to about 6.2, about 5.3 to about 6.1, about 5.4 to about 6.0, about 5.5 to about 5.9, about 5.6 to about 5.8 or about 5, 7.
91. Composition according to any one of claims 1 to 87, characterized in that it has a pH of about 5.3 to about 6.8, about 5.5 to about 6.5, about 5.6 to about 6.4, about 5.7 to about 6.3, about 5.8 to about 6.2, about 5.9 to about 6.1 or about 6, 0.
92. Composition according to any one of claims 1 to 91, characterized by the fact that it has a stability of about 1 day, about 2 days, 3 days,
4 days, 5 days, 6 days, 7 days, 8 days, 9 days, 10 days, 11 days, 12 days, 13 days, 14 days or 15 days, or at least 1 day, at least 2 days, at least 3 days, at least 4 days,
at least 5 days, at least 6 days, at least 7 days,
at least 8 days, at least 9 days, at least 10 days,
at least 11 days, at least 12 days, at least 13 days,
at least 14 days or at least 15 days, or at most 1 day, at most 2 days, at most 3 days, at most 4 days,
maximum 5 days, maximum 6 days, maximum 7 days, maximum 8 days, maximum 9 days, maximum 10 days, maximum
11 days, maximum 12 days, maximum 13 days, maximum 14 days or maximum 15 days or about 1 day to about 2 days, about 1 day to about 3 days, about 1 day to about 4 days, about 1 day to about 5 days, about
1 day to about 6 days, about 1 day to about 7 days,
about 1 day to about 8 days, about 1 day to about
9 days, about 1 day to about 10 days, about 1 day to about 11 days, about 1 day to about 12 days, about 1 day to about 13 days, about 1 day to about 14 days, about 1 day to about 15 days, about 2 days to about 3 days, about 2 days to about 4 days, about
2 days to about 5 days, about 2 days to about 6 days,
about 2 days to about 7 days, about 2 days to about 8 days, about 2 days to about 9 days, about 2 days to about 10 days, about 2 days to about 11 days,
about 2 days to about 12 days, about 2 days to about 13 days, about 2 days to about 14 days, about 2 days to about 15 days, about 3 days to about 4 days,
about 3 days to about 5 days, about 3 days to about 6 days, about 3 days to about 7 days, about 3 days to about 8 days, about 3 days to about 9 days,
about 3 days to about 10 days, about 3 days to about 11 days, about 3 days to about 12 days, about 3 days to about 13 days, about 3 days to about 14 days,
about 3 days to about 15 days, about 4 days to about 5 days, about 4 days to about 6 days, about 4 days to about 7 days, about 4 days to about 8 days,
about 4 days to about 9 days, about 4 days to about 10 days, about 4 days to about 11 days, about 4 days to about 12 days, about 4 days to about 13 days,
about 4 days to about 14 days, about 4 days to about 15 days, about 5 days to about 6 days, about 5 days to about 7 days, about 5 days to about 8 days,
about 5 days to about 9 days, about 5 days to about 10 days, about 5 days to about 11 days, about 5 days to about 12 days, about 5 days to about 13 days,
about 5 days to about 14 days, about 5 days to about 15 days, about 6 days to about 7 days, about 6 days to about 8 days, about 6 days to about 9 days,
about 6 days to about 10 days, about 6 days to about 11 days, about 6 days to about 12 days, about 6 days to about 13 days, about 6 days to about 14 days,
about 6 days to about 15 days, about 7 days to about 8 days, about 7 days to about 9 days, about 7 days to about 10 days, about 7 days to about 11 days,
about 7 days to about 12 days, about 7 days to about 13 days, about 7 days to about 14 days, about 7 days to about 15 days, about 8 days to about 9 days,
about 8 days to about 10 days, about 8 days to about 11 days, about 8 days to about 12 days, about 8 days to about 13 days, about 8 days to about 14 days,
about 8 days to about 15 days, about 9 days to about 10 days, about 9 days to about 11 days, about 9 days to about 12 days, about 9 days to about 13 days,
about 9 days to about 14 days, about 9 days to about 15 days, about 10 days to about 11 days, about 10 days to about 12 days, about 10 days to about 13 days,
about 10 days to about 14 days, about 10 days to about 15 days, about 11 days to about 12 days, about 11 days to about 13 days, about 11 days to about 14 days,
about 11 days to about 15 days, about 12 days to about 13 days, about 12 days to about 14 days, about 12 days to about 15 days, about 13 days to about 14 days,
about 13 days to about 15 days, or about 14 days to about 15 days.
93. Composition according to any one of claims 1 to 91, characterized by the fact that it has a stability of about 1 week, about 2 weeks, 3 weeks, 4 weeks, 5 weeks, 6, weeks, 7 weeks, 8 weeks, 9 weeks, 10 weeks, 11 weeks, 12 weeks, 13 weeks, 14 weeks or 15 weeks, or at least 1 week, at least 2 weeks, at least 3 weeks, at least 4 weeks, at least 5 weeks, at least 6 weeks, at least 7 weeks, at least 8 weeks, at least 9 weeks, at least 10 weeks, at least 11 weeks, at least 12 weeks, at least 13 weeks, at least 14 weeks or at least 15 weeks , or maximum 1 week, maximum 2 weeks, maximum 3 weeks, maximum 4 weeks, maximum 5 weeks, maximum 6 weeks, maximum 7 weeks, maximum 8 weeks, maximum 9 weeks 10 weeks, maximum 11 weeks, maximum 12 weeks, maximum 13 weeks, maximum 14 weeks or maximum 15 weeks or about 1 week about 2 weeks, about 1 week to about 3 weeks, about 1 week to about 4 weeks, about 1 week to about 5 weeks, about 1 week to about 6 weeks, about 1 week about 7 weeks, about 1 week about 8 weeks, about 1 week about 9 weeks, about 1 week about 10 weeks,
about 1 week to about 11 weeks, about 1 week to about 12 weeks, about 1 week to about 13 weeks, about 1 week to about 14 weeks, about
1 week to about 15 weeks, about 2 weeks to about 3 weeks, about 2 weeks to about 4 weeks, about 2 weeks to about 5 weeks, about 2 weeks to about 6 weeks, about 2 weeks to about 7 weeks, about 2 weeks to about 8 weeks, about 2 weeks to about 9 weeks, about 2 weeks to about 10 weeks, about 2 weeks to about 11 weeks, about 2 weeks to about 12 weeks, about 2 weeks to about 13 weeks,
about 2 weeks to about 14 weeks, about 2 weeks to about 15 weeks, about 3 weeks to about 4 weeks, about 3 weeks to about 5 weeks, about
3 weeks to about 6 weeks, about 3 weeks to about 7 weeks, about 3 weeks to about 8 weeks, about 3 weeks to about 9 weeks, about 3 weeks to about 10 weeks, about 3 weeks to about 11 weeks,
about 3 weeks to about 12 weeks, about 3 weeks to about 13 weeks, about 3 weeks to about 14 weeks, about 3 weeks to about 15 weeks, about
4 weeks to about 5 weeks, about 4 weeks to about 6 weeks, about 4 weeks to about 7 weeks, about 4 weeks to about 8 weeks, about 4 weeks to about 9 weeks, about 4 weeks to about 10 weeks, about 4 weeks to about 11 weeks, about 4 weeks to about 12 weeks, about 4 weeks to about 13 weeks,
about 4 weeks to about 14 weeks, about 4 weeks to about 15 weeks, about 5 weeks to about 6 weeks, about 5 weeks to about 7 weeks, about
5 weeks to about 8 weeks, about 5 weeks to about 9 weeks, about 5 weeks to about 10 weeks, about 5 weeks to about 11 weeks, about 5 weeks to about 12 weeks, about 5 weeks to about 13 weeks,
about 5 weeks to about 14 weeks, about 5 weeks to about 15 weeks, about 6 weeks to about 7 weeks, about 6 weeks to about 8 weeks, about
6 weeks to about 9 weeks, about 6 weeks to about 10 weeks, about 6 weeks to about 11 weeks,
about 6 weeks to about 12 weeks, about 6 weeks to about 13 weeks, about 6 weeks to about 14 weeks, about 6 weeks to about 15 weeks, about
7 weeks to about 8 weeks, about 7 weeks to about 9 weeks, about 7 weeks to about 10 weeks, about 7 weeks to about 11 weeks, about 7 weeks to about 12 weeks, about 7 weeks to about 13 weeks,
about 7 weeks to about 14 weeks, about 7 weeks to about 15 weeks, about 8 weeks to about 9 weeks, about 8 weeks to about 10 weeks, about
8 weeks to about 11 weeks, about 8 weeks to about 12 weeks, about 8 weeks to about 13 weeks, about 8 weeks to about 14 weeks, about 8 weeks to about 15 weeks, about 9 weeks to about 10 weeks, about 9 weeks to about 11 weeks, about 9 weeks to about 12 weeks, about 9 weeks to about 13 weeks, about 9 weeks to about 14 weeks, about 9 weeks to about 15 weeks, about 10 weeks to about 11 weeks, about 10 weeks to about 12 weeks, about 10 weeks to about 13 weeks, about 10 weeks to about 14 weeks, about 10 weeks to about 15 weeks, about 11 weeks to about 12 weeks, about 11 weeks to about 13 weeks, about 11 weeks to about 14 weeks, about 11 weeks to about 15 weeks, about 12 weeks to about 13 weeks, about 12 weeks to about 14 weeks, about 12 weeks to about 15 weeks, about 13 weeks to about 14 weeks, about 13 weeks to about 15 weeks, or about 14 weeks to about 15 weeks.
94. Composition according to any one of claims 1 to 91, characterized by the fact that it has a stability of about 1 month, about 2 months, 3 months, 4 months, 5 months, 6 months, 7 months, 8 months, 9 months, 10 months, 11 months, 12 months, 13 months, 14 months or 15 months, or at least 1 month, at least 2 months, at least 3 months, at least 4 months, at least 5 months, at least least 6 months,
at least 7 months, at least 8 months, at least 9 months,
at least 10 months, at least 11 months, at least 12 months, at least 13 months, at least 14 months or at least
15 months, or at most 1 month, at most 2 months, at most
3 months, maximum 4 months, maximum 5 months, maximum 6
months, maximum 7 months, maximum 8 months, maximum 9 months, maximum 10 months, maximum 11 months, maximum 12 months, maximum 13 months, maximum 14 months or maximum
15 months or about 1 month to about 2 months, about 1 month to about 3 months, about 1 month to about 4 months,
about 1 month to about 5 months, about 1 month to about
6 months, about 1 month to about 7 months, about 1 month to about 8 months, about 1 month to about 9 months, about 1 month to about 10 months, about 1 month to about 11 months, about 1 month to about 12 months, about 1 month to about 13 months, about 1 month to about 14 months, about 1 month to about 15 months, about 2 months to about 3 months, about 2 months to about 4 months, about 2 months to about 5 months, about 2 months to about 6 months,
about 2 months to about 7 months, about 2 months to about 8 months, about 2 months to about 9 months, about 2 months to about 10 months, about 2 months to about 11 months, about 2 months to about 12 months, about 2 months to about 13 months, about 2 months to about 14 months,
about 2 months to about 15 months, about 3 months to about 4 months, about 3 months to about 5 months, about 3 months to about 6 months, about 3 months to about
7 months, about 3 months to about 8 months, about 3 months to about 9 months, about 3 months to about 10 months, about 3 months to about 11 months, about 3 months to about 12 months, about 3 months to about 13 months,
about 3 months to about 14 months, about 3 months to about 15 months, about 4 months to about 5 months, about 4 months to about 6 months, about 4 months to about
7 months, about 4 months to about 8 months, about 4 months to about 9 months, about 4 months to about 10 months, about 4 months to about 11 months, about 4 months to about 12 months, about 4 months to about 13 months,
about 4 months to about 14 months, about 4 months to about 15 months, about 5 months to about 6 months, about 5 months to about 7 months, about 5 months to about
8 months, about 5 months to about 9 months, about 5 months to about 10 months, about 5 months to about 11 months, about 5 months to about 12 months, about 5 months to about 13 months, about 5 months to about 14 months,
about 5 months to about 15 months, about 6 months to about 7 months, about 6 months to about 8 months, about 6 months to about 9 months, about 6 months to about
10 months, about 6 months to about 11 months, about 6 months to about 12 months, about 6 months to about 13 months, about 6 months to about 14 months, about 6 months to about 15 months, about 7 months to about 8 months,
about 7 months to about 9 months, about 7 months to about 10 months, about 7 months to about 11 months, about
7 months to about 12 months, about 7 months to about 13 months, about 7 months to about 14 months, about 7 months to about 15 months, about 8 months to about 9 months,
about 8 months to about 10 months, about 8 months to about 11 months, about 8 months to about 12 months,
about 8 months to about 13 months, about 8 months to about 14 months, about 8 months to about 15 months,
about 9 months to about 10 months, about 9 months to about 11 months, about 9 months to about 12 months,
about 9 months to about 13 months, about 9 months to about 14 months, about 9 months to about 15 months,
about 10 months to about 11 months, about 10 months to about 12 months, about 10 months to about 13 months,
about 10 months to about 14 months, about 10 months to about 15 months, about 11 months to about 12 months,
about 11 months to about 13 months, about 11 months to about 14 months, about 11 months to about 15 months,
about 12 months to about 13 months, about 12 months to about 14 months, about 12 months to about 15 months,
about 13 months to about 14 months, about 13 months to about 15 months, or about 14 months to about 15 months.
95. Composition according to any one of claims 1 to 91, characterized by the fact that it has a stability of about 1 year, about 2 years, about 3 years, about 4 years or about 5 years, or at least 1 year, at least 2 years, at least 3 years, at least 4 years or at least 5 years, or at most 1 year, at most 2 years, at most 3 years, at most 4 years or at most 5 years or about 1 year to about 2 years, about 1 year to about 3 years, about 1 year to about 4 years, about 1 year to about 5 years, about 2 years to about 3 years , about 2 years to about 4 years, about 2 years to about 5 years, about 3 years to about 4 years, about 3 years to about 5 years or about 4 years to about 5 years .
96. Composition according to any one of claims 1 to 95, the composition of which is characterized by the fact that it does not comprise, essentially consists of, or consists of ozone.
97. Composition according to any one of claims 1 to 96, the composition of which is characterized by the fact that it does not comprise, essentially consists of, or consists of hydrogen peroxide.
98. Composition according to any one of claims 1 to 97, the composition of which is characterized by the fact that it does not comprise, essentially consists of, or consists of available hypochlorous acid or chlorine.
99. Composition according to any one of claims 1 to 98, the composition of which is characterized by the fact that it does not understand, essentially consists of, or consists of a surfactant.
100. Composition according to any one of claims 1 to 99, the composition of which is characterized by the fact that it does not understand, essentially consists of, or consists of a surfactant.
101. Composition according to any one of claims 1 to 100, the composition of which is characterized by the fact that it does not comprise, essentially consists of, or consists of a compound containing guanide.
102. Composition according to any one of claims 1 to 101, the composition being characterized by the fact that it does not comprise, essentially consists of, or consists of compounds containing aldehyde.
103. Composition according to any one of claims 1 to 102, characterized in that it is formulated as a single-phase formulation or a biphasic formulation.
104. Composition according to any one of claims 1 to 103, characterized in that it is formulated as a liquid composition, a colloidal composition, a semi-solid composition or a solid composition.
105. Composition according to any one of claims 1 to 104, characterized in that it is formulated as a liquid aerosol, foam, emulsion, gel, sun or solid sun.
106. Composition according to any one of claims 1 to 105, characterized in that it is formulated as a spray, a liquid aerosol, a wash, a lotion, a cream, a soap, a dry powder, a steam or a suspension.
107. Kit characterized by the fact that it comprises, essentially consists of, or consists of a composition as defined in any one of claims 1 to
106.
108. Kit according to claim 107, characterized in that it further comprises, essentially consists of or consists of one or more distribution or application systems, and / or instructions and / or a container.
109. Kit characterized by the fact that it comprises, consists essentially of, or consists of a first component that includes available free chlorine or hypochlorous acid and a second component that includes one or more disinfectants.
110. Kit characterized by the fact that it comprises, essentially consists of, or consists of a first component that includes one or more alcohols and a second component that includes one or more disinfectants.
111. Kit characterized by the fact that it comprises, essentially consists of, or consists of a first component that includes isopropyl alcohol and a second component that includes polyhexamethylene biguanide.
112. Kit according to any one of claims 109 to 111, characterized in that it further comprises, essentially consists of or consists of a third component that includes one or more cationic surfactants, and / or a fourth component that includes a solution of rinse and / or one or more distribution or application systems, and / or instructions and / or a container.
113. Kit according to claim 109 or 112, characterized in that the available free chlorine or hypochlorous acid is in an amount of about 0.00005%, about 0.00006%, about 0.00007% , about 0.000075%, about 0.00008%, about 0.00009%, about 0.0001%, about 0.0005%, about 0.001%, about 0.0015%, about 0.002%, about 0.0025%, about 0.003%, about 0.0035%, about 0.004%, about 0.0045%, about 0.005%, about 0.0055%, about 0.006% , about 0.007%, about 0.0075%, about 0.008%, about 0.009%, about 0.01%, about
0.02%, about 0.03%, about 0.04%, about 0.05%, about 0.06%, about 0.07%, about 0.075%, about 0.08 %,
about 0.09%, about 0.10%, about 0.11%, about
0.12%, about 0.13%, about 0.14% or about 0.15% by weight of the composition, or at least 0.00005%, at least
0.00006%, at least 0.00007%, at least 0.000075%, at least 0.00008%, at least 0.00009%, at least 0.0001%,
at least 0.0005%, at least 0.001%, at least 0.0015%,
at least 0.002%, at least 0.0025%, at least 0.003%,
at least 0.0035%, at least 0.004%, at least 0.0045%,
at least 0.005%, at least 0.0055%, at least 0.006%,
at least 0.007%, at least 0.0075%, at least 0.008%,
at least 0.009%, at least 0.01%, at least 0.02%, at least 0.03%, at least 0.04%, at least 0.05%, at least
0.06%, at least 0.07%, at least 0.075%, at least 0.08%,
at least 0.09%, at least 0.10%, at least 0.11%, at least 0.12%, at least 0.13%, at least 0.14% or at least
0.15% by weight of the composition, or a maximum of 0.00005%, a maximum
0.00006%, maximum 0.00007%, maximum 0.000075%, maximum
0.00008%, maximum 0.00009%, maximum 0.0001%, maximum
0.0005%, maximum 0.001%, maximum 0.0015%, maximum
0.002%, maximum 0.0025%, maximum 0.003%, maximum
0.0035%, maximum 0.004%, maximum 0.0045%, maximum
0.005%, maximum 0.0055%, maximum 0.006%, maximum
0.007%, maximum 0.0075%, maximum 0.008%, maximum
0.009%, maximum 0.01%, maximum 0.02%, maximum 0.03%, maximum 0.04%, maximum 0.05%, maximum 0.06%, maximum 0.07 %, maximum 0.075%, maximum 0.08%, maximum 0.09%, maximum 0.10%, maximum 0.11%, maximum 0.12%, maximum 0.13%, maximum 0.14% or maximum 0.15% by weight of the composition or about 0.00075% to about 0.002%, about 0.00075% to about 0.003%, about 0.00075% to about 0.004%, about 0.00075% to about 0.005%, about 0.00075% to about 0.006%, about 0.00075% to about 0.007%, about 0.00075% to about 0.008% , about 0.00075% to about 0.009%, about 0.00075% to about 0.01%, about 0.001% to about 0.002%, about 0.001% to about 0.003%, about 0.001 % to about 0.004%, about 0.001% to about 0.005%, about 0.001% to about 0.006%, about 0.001% to about 0.007%, about 0.001% to about 0.008%, about 0.001 % to about 0.009%, about 0.001% to about 0.01%, about 0.002% to about 0.003%, about 0.0 02% to about 0.004%, about 0.002% to about 0.005%, about 0.002% to about 0.006%, about 0.002% to about 0.007%, about 0.002% to about 0.008%, about 0.002% to about 0.009%, about 0.002% to about 0.01% by weight of the composition
114. Kit according to claim 109 or 112, characterized in that the available hypochlorous acid or free chlorine is in an amount of 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm, 0.30 ppm, 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm, 0.80 ppm, 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm , 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1,000 ppm, 1,025 ppm, 1,050 ppm, 1,075 ppm, 1,100 ppm, 1,125 ppm, 1,150 ppm, 1,175 ppm, 1,200 ppm, 1,225 ppm,
1,250 ppm, 1,275 ppm, 1,300 ppm, 1,325 ppm, 1,350 ppm, 1,375 ppm, 1,400 ppm, 1,425 ppm, 1,450 ppm, 1,475 ppm, or 1,500 ppm, or at least 0.05 ppm, at least 0.10 ppm, at least at least 0.20 ppm, at least 0.30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least 0.80 ppm, at least 0.90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm, at least 40 ppm, at least 50 ppm, at least 60 ppm, at least 70 ppm, at least 80 ppm, at least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm,
at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1,000 ppm, at least 1,025 ppm, at least 1,050 ppm, at least 1,075 ppm, at least 1,100 ppm, at least
1,125 ppm, at least 1,150 ppm, at least 1,175 ppm, at least 1,200 ppm, at least 1,225 ppm, at least 1,250 ppm, at least 1,275 ppm, at least 1,300 ppm, at least 1,325 ppm, at least 1,350 ppm, at least 1,375 ppm at least
1,400 ppm, at least 1,425 ppm, at least 1,450 ppm, at least 1,475 ppm or at least 1,500 ppm, or at most 0.05 ppm, at most 0.10 ppm, at most 0.20 ppm, at most 0.30 ppm, maximum 0.40 ppm, maximum 0.50 ppm, maximum 0.60 ppm, maximum 0.70 ppm, maximum 0.80 ppm, maximum 0.90 ppm, maximum 1 ppm, no maximum 10 ppm, maximum 20 ppm, maximum 30 ppm, maximum 40 ppm, maximum 50 ppm, maximum 60 ppm, maximum 70 ppm, maximum 80 ppm, maximum 90 ppm, maximum 100 ppm, no maximum 125 ppm, maximum 150 ppm, maximum 175 ppm, maximum 200 ppm, maximum 225 ppm, maximum 250 ppm, maximum 275 ppm, maximum 300 ppm, maximum 325 ppm, maximum 350 ppm, no maximum 375 ppm, maximum 400 ppm, maximum 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm, maximum 550 ppm, maximum 575 ppm, maximum 600 ppm, no maximum 625 ppm, maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, m maximum 775 ppm, maximum 800 ppm, maximum 825 ppm, maximum 850 ppm, maximum 875 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm, maximum 1,000 ppm maximum 1,025 ppm maximum
1,050 ppm, at most 1,075 ppm, at most 1,100 ppm, at most 1,125 ppm, at most 1,150 ppm, at most 1,175 ppm, at most 1,200 ppm, at most 1,225 ppm, at most 1,250 ppm, at most 1,275 ppm, at most 1,300 ppm maximum
1,325 ppm, at most 1,350 ppm, at most 1,375 ppm, at most 1,400 ppm, at most 1,425 ppm, at most 1,450 ppm, at most 1,475 ppm or at most 1,500 ppm, or about 0.5 ppm at about 20 ppm, about 0.5 ppm to about 25 ppm, about 0.5 ppm to about 30 ppm, about 0.5 ppm to about 35 ppm, about 0.5 ppm to about 40 ppm, about 0.5 ppm to about 45 ppm, about 0.5 ppm to about 50 ppm, about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 60 ppm, about 0, 5 ppm to about 65 ppm, about 0.5 ppm to about 70 ppm, about 0.5 ppm to about 75 ppm,
about 0.5 ppm to about 80 ppm, about 0.5 ppm to about 85 ppm, about 0.5 ppm to about 90 ppm, about 0.5 ppm to about 95 ppm, about 0.5 ppm to about 100 ppm,
about 0.75 ppm to about 20 ppm, about 0.75 ppm to about 25 ppm, about 0.75 ppm to about 30 ppm, about 0.75 ppm to about 35 ppm, about 0.75 ppm at about
40 ppm, about 0.75 ppm to about 45 ppm, about 0.75 ppm to about 50 ppm, about 0.75 ppm to about 55 ppm,
about 0.75 ppm to about 60 ppm, about 0.75 ppm to about 65 ppm, about 0.75 ppm to about 70 ppm, about 0.75 ppm to about 75 ppm, about 0.75 ppm at about
80 ppm, about 0.75 ppm to about 85 ppm, about 0.75 ppm to about 90 ppm, about 0.75 ppm to about 95 ppm,
about 0.75 ppm to about 100 ppm, about 1 ppm to about 20 ppm, about 1 ppm to about 25 ppm, about 1 ppm to about 30 ppm, about 1 ppm to about 35 ppm, about 1 ppm to about 40 ppm, about 1 ppm to about 45 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 55 ppm, about 1 ppm to about 60 ppm, about 1 ppm to about 65 ppm, about 1 ppm to about 70 ppm, about 1 ppm to about 75 ppm, about 1 ppm to about 80 ppm, about 1 ppm to about 85 ppm, about 1 ppm to about 90 ppm, about 1 ppm to about 95 ppm, about 1 ppm to about 100 ppm, about 5 ppm to about 20 ppm, about 5 ppm to about 25 ppm, about 5 ppm to about 30 ppm, about 5 ppm to about 35 ppm, about 5 ppm to about 40 ppm, about 5 ppm to about 45 ppm, about 5 ppm to about 50 ppm, about 5 ppm to about 55 ppm, about 5 ppm to about 60 ppm, about 5 ppm to about 65 ppm, about 5 ppm to about 70 ppm, about 5 ppm to about 75 ppm, about 5 ppm to about 80 ppm, about 5 ppm to about 85 ppm, about 5 ppm to about 90 ppm, about 5 ppm to about 95 ppm, about 5 ppm to about 100 ppm, about 10 ppm to about 20 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 30 ppm, about
10 ppm to about 35 ppm, about 10 ppm to about 40 ppm,
about 10 ppm to about 45 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 55 ppm, about 10 ppm to about 60 ppm, about 10 ppm to about 65 ppm,
about 10 ppm to about 70 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 80 ppm, about 10 ppm to about 85 ppm, about 10 ppm to about 90 ppm,
about 10 ppm to about 95 ppm, or about 10 ppm to about 100 ppm or about 1 ppm to about 25 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 75 ppm ,
about 1 ppm to about 100 ppm, about 1 ppm to about
125 ppm, about 1 ppm to about 150 ppm, about 1 ppm to about 175 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, about 1 ppm to about 250 ppm, about 1 ppm to about 275 ppm, about 1 ppm to about 300 ppm, about 1 ppm to about 325 ppm, about 1 ppm to about 350 ppm, about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about
10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, about 10 ppm to about 125 ppm, about 10 ppm to about 150 ppm, about 10 ppm to about 175 ppm, about 10 ppm to about 200 ppm, about 10 ppm to about 225 ppm, about 10 ppm to about 250 ppm, about 10 ppm to about 275 ppm, about 10 ppm to about 300 ppm, about 10 ppm to about 325 ppm, about 10 ppm to about 350 ppm, about 10 ppm to about 375 ppm, about 10 ppm to about 400 ppm, about 25 ppm to about 50 ppm, about 25 ppm to about 75 ppm, about 25 ppm to about 100 ppm, about 25 ppm to about 125 ppm, about 25 ppm to about 150 ppm, about 25 ppm to about 175 ppm, about 25 ppm to about 200 ppm, about 25 ppm to about 225 ppm, about 25 ppm to about 250 ppm, about 25 ppm to about 275 ppm, about 25 ppm to about 300 ppm, about 25 ppm to about 325 ppm, about 25 ppm to about 350 ppm, about 25 ppm to about 375 ppm, about from 25 ppm to about 400 ppm, about 50 ppm to about 75 ppm, about 50 ppm to about 100 ppm, about 50 ppm to about 125 ppm, about 50 ppm to about 150 ppm, about 50 ppm to about 175 ppm, about 50 ppm to about 200 ppm, about 50 ppm to about 225 ppm, about 50 ppm to about 250 ppm, about 50 ppm to about 275 ppm, about 50 ppm to about 300 ppm, about 50 ppm to about 325 ppm, about 50 ppm to about 350 ppm, about 50 ppm to about 375 ppm, about 50 ppm to about 400 ppm, about 75 ppm to about 100 ppm, about 75 ppm to about 125 ppm, about 75 ppm to about 150 ppm, about 75 ppm to about 175 ppm, about 75 ppm to about 200 ppm, about 75 ppm to about 225 ppm, about 75 ppm to about 250 ppm, about 75 ppm to about 275 ppm, about 75 ppm to about 300 ppm, about 75 ppm to about 325 ppm, about 75 ppm to about 350 ppm, about 75 ppm to about 375 ppm, about 75 ppm to about 400 pp m, about 100 ppm to about
125 ppm, about 100 ppm to about 150 ppm, about 100 ppm to about 175 ppm, about 100 ppm to about 200 ppm,
about 100 ppm to about 225 ppm, about 100 ppm to about 250 ppm, about 100 ppm to about 275 ppm, about
100 ppm to about 300 ppm, about 100 ppm to about 325 ppm, about 100 ppm to about 350 ppm, about 100 ppm to about 375 ppm, about 100 ppm to about 400 ppm,
about 150 ppm to about 175 ppm, about 150 ppm to about 200 ppm, about 150 ppm to about 225 ppm, about
150 ppm to about 250 ppm, about 150 ppm to about 275 ppm, about 150 ppm to about 300 ppm, about 150 ppm to about 325 ppm, about 150 ppm to about 350 ppm,
about 150 ppm to about 375 ppm, about 150 ppm to about 400 ppm, about 200 ppm to about 225 ppm, about
200 ppm to about 250 ppm, about 200 ppm to about 275 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 325 ppm, about 200 ppm to about 350 ppm,
about 200 ppm to about 375 ppm, about 200 ppm to about 400 ppm, about 250 ppm to about 275 ppm, about
250 ppm to about 300 ppm, about 250 ppm to about 325 ppm, about 250 ppm to about 350 ppm, about 250 ppm to about 375 ppm, about 250 ppm to about 400 ppm,
about 300 ppm to about 325 ppm, about 300 ppm to about 350 ppm, about 300 ppm to about 375 ppm, about
300 ppm to about 400 ppm, about 350 ppm to about 375 ppm, about 350 ppm to about 400 ppm, about 375 ppm to about 400 ppm, about 400 ppm to about 500 ppm,
about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about
400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 400 ppm to about 1,100 ppm, about 400 ppm to about 1,200 ppm, about 400 ppm to about 1,300 ppm,
about 400 ppm to about 1,400 ppm, about 400 ppm to about 1,500 ppm, about 500 ppm to about 600 ppm,
about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about
500 ppm to about 1,000 ppm, about 500 ppm to about
1,100 ppm, about 500 ppm to about 1,200 ppm, about 500 ppm to about 1,300 ppm, about 500 ppm to about
1,400 ppm, about 500 ppm to about 1,500 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 1,000 ppm, about 600 ppm to about 1,100 ppm, about 600 ppm to about 1,200 ppm, about 600 ppm to about 1,300 ppm, about 600 ppm to about 1,400 ppm, about 600 ppm to about 1,500 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 700 ppm to about
1,100 ppm, about 700 ppm to about 1,200 ppm, about 700 ppm to about 1,300 ppm, about 700 ppm to about
1,400 ppm, about 700 ppm to about 1,500 ppm, about 800 ppm to about 900 ppm, about 800 ppm to about 1,000 ppm, about 800 ppm to about 1,100 ppm, about 800 ppm to about 1,200 ppm, about 800 ppm to about 1,300 ppm, about 800 ppm to about 1,400 ppm, about 800 ppm to about 1,500 ppm, about 900 ppm to about 1,000 ppm, about 900 ppm to about 1,100 ppm, about 900 ppm to about 1,200 ppm, about 900 ppm to about 1,300 ppm, about 900 ppm to about 1,400 ppm, about 900 ppm to about 1,500 ppm, about 1,000 ppm to about 1,100 ppm, about 1,000 ppm to about 1,200 ppm, about 1,000 ppm to about 1,300 ppm, about 1,000 ppm to about 1,400 ppm, about 1,000 ppm to about 1,500 ppm, about 1,100 ppm to about 1,200 ppm, about 1,100 ppm to about 1,300 ppm, about 1,100 ppm to about 1,400 ppm, about 1,100 ppm to about 1,500 ppm, about 1,200 ppm to about 1,300 ppm, about 1,200 ppm to about 1,400 ppm, about 1,200 ppm to about 1,500 ppm, about 1,300 ppm to about 1,400 ppm, about 1,300 ppm to about 1,500 ppm or about
1,400 ppm to about 1,500 ppm.
115. Kit according to any one of claims 109, 110 or 112 to 114, characterized in that the one or more disinfectants are in an amount of about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 0.7 %, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0%, about 2.5%, about 3.0% , about 4.0%, about 5.0%, about 6.0%, about 7.0%, about 7.5%, about 8.0%, about 9.0% or about 10.0% by weight of the composition, or at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1%, at least 0.25%, at least 0.5 %, at least 0.75%, at least 1.0%, at least 1.5%, at least 2.0%, at least 2.5%, at least 3.0%, at least 4.0% at least 5.0%, at least 6.0%, at least 7.0%, at least 7.5%, at least 8.0%, at least 9.0% or at least 10.0% in weight of the composition, or at most 0.01%, at most 0.05%, at most 0.075%, in the maximum 0.1%, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum
1.0%, maximum 1.5%, maximum 2.0%, maximum 2.5%, maximum 3.0%, maximum 4.0%, maximum 5.0%, maximum 6 , 0%,
maximum 7.5%, maximum 8.0%, maximum 9.0% or maximum
10.0% by weight of the composition or about 0.1% to about 0.5%,
about 0.1% to about 0.75%, about 0.1% to about
1.0%, about 0.1% to about 1.5%, about 0.1% to about 2.0%, about 0.1% to about 2.5%, about 0 , 2% to about 0.5%, about 0.2% to about 0.75%, about 0.2% to about 1.0%, about 0.2% to about 1, 5%, about 0.2%
about 2.0%, about 0.2% to about 2.5%, about
0.5% to about 1.0%, about 0.5% to about 1.5%, about 0.5% to about 2.0%, about 0.5% to about 2 , 5%, about 0.5% to about 3.0%, about 0.5% to about 4.0%, about 0.5% to about 5.0%, about 1, 0% to about 2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0 %, about 1.0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%, about 1.0% about 8.0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 2.0% to about 2.5%,
about 2.0% to about 3.0%, about 2.0% to about 4.0%,
about 2.0% to about 5.0%, about 2.0% to about 6.0%,
about 2.0% to about 7.0%, about 2.0% to about 7.5%,
about 2.0% to about 8.0%, about 2.0% to about 9.0%,
about 2.0% to about 10.0%, about 5.0% to about
6.0%, about 5.0% to about 7.0%, about 5.0% to about 7.5%, about 5.0% to about 8.0%, about 5 , 0% to about 9.0%, about 5.0% to about 10.0%, about 5.0% to about 11.0%, about 5.0% to about 12, 0%, about 5.0% to about 13.0%, about 5.0% to about 14.0% or about 5.0% to about 15.0% by weight of the composition.
116. Kit according to any one of claims 109, 110 or 112 to 114, characterized in that the one or more disinfectants are in an amount of about 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm , 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm or 1,000 ppm, or at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least and at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least
850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm or at least
1,000 ppm, or at most 100 ppm, at most 125 ppm, at most 150 ppm, at most 175 ppm, at most 200 ppm, at most 225 ppm, at most 250 ppm, at most 275 ppm, at most 300 ppm, in maximum 325 ppm, maximum 350 ppm, maximum 375 ppm, maximum 400 ppm, maximum 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm, maximum 550 ppm, no maximum 575 ppm, maximum 600 ppm, maximum 625 ppm, maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, maximum 775 ppm, maximum 800 ppm, no maximum 825 ppm, maximum 850 ppm, maximum 875 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm or maximum 1,000 ppm or about 100 ppm at about 200 ppm, approximately from 100 ppm to about 300 ppm, about 100 ppm to about 400 ppm, about 100 ppm to about 500 ppm, about 100 ppm to about 600 ppm, about 100 ppm to about 700 ppm, about from 100 ppm to about 800 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 1,000 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 400 ppm, about 200 ppm to about 500 ppm, about 200 ppm to about 600 ppm, about 200 ppm to about 700 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 900 ppm, about 200 ppm to about 1,000 ppm, about 300 ppm to about 400 ppm, about 300 ppm to about 500 ppm, about 300 ppm to about 600 ppm, about 300 ppm to about 700 ppm, about 300 ppm to about 800 ppm, about 300 ppm to about 900 ppm, about 300 ppm to about 1,000 ppm, about 400 ppm to about 500 ppm, about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm, about 500 ppm to about 600 ppm, about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about 50 0 ppm to about 1,000 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 1,000 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 800 ppm to about 900 ppm, about 800 ppm to about 1,000 ppm or about 900 ppm to about 1,000 ppm.
117. Kit according to any one of claims 109, 110 or 112 to 116, characterized in that the one or more disinfectants include one or more compounds containing a fraction of guanide or functional group, one or more compounds containing aldehyde , one or more organic peroxides or any combination thereof.
118. Kit according to claim 117,
characterized by the fact that the one or more guanide-containing compounds comprise, essentially consist of or consist of a biguanide, a compound containing biguanide, a biguanidine, a compound containing biguanidine, a triguanide, a compound containing triguanide or any combination thereof.
119. Kit according to claim 118, characterized by the fact that the one or more compounds containing biguanide include a polyhexamethylene biguanide (PHMB), a polyaminopropyl biguanide (PAPB), a 1.1 '- (1, 6-hexanediyl) bis {2- [N '- (2-ethylhexyl) carbamimidoyl] guanidine} (alexidine), a chlorhexidine, a chlorhexidine gluconate or any combination thereof.
120. Kit according to claim 117, characterized in that the one or more compounds containing aldehyde include one or more aldehydes, one or more dialdehydes or any combination thereof.
121. Kit according to claim 120, characterized in that the one or more aldehydes include one or more linear aldehydes, one or more branched aldehydes, one or more cyclic aldehydes, one or more aromatic aldehydes or any combination thereof .
122. Kit according to claim 120 or 121, characterized in that the one or more aldehydes include formaldehyde, acetaldehyde, propionaldehyde, butyraldehyde or any combination thereof.
123. Kit according to claim 120, characterized in that the one or more dialdehydes include one or more linear dialdehydes, one or more branched dialdehydes, one or more cyclic dialdehydes, one or more aromatic dialdehydes or any combination thereof .
124. Kit according to claim 120 or 121, characterized in that the one or more dialdehydes include oxaldehyde, malondialdehyde, glutaraldehyde, succinic dialdehyde, phthalaldehyde (ortho-phthalaldehyde), isophthalaldehyde (meta-phthalaldehyde), tereftalaldehyde (for phthalaldehyde) or any combination thereof.
125. Kit according to claim 117, characterized in that the one or more organic peroxides include benzoyl peroxide, ethanoperoxoic acid (peracetic acid) or any combination thereof.
126. Kit according to any one of claims 117 to 125, characterized in that the one or more compounds containing guanide, the one or more compounds containing aldehyde and / or one or more organic peroxides are in an amount of about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0, 5%, about 0.6%, about 0.7%, about 0.8%, about 0.9%, about 1.0%, about 1.5%, about 2.0 %, about 2.5%, about 3.0%, about 4.0%, about 5.0%, about 6.0%, about 6.5%, about 7.0% , about 7.5%, about 8.0%, about 8.5%, about 9.0%, about 9.5%, about 10.0%. about 11%, about 12%, about 13%, about 14%, about 15%, about 20%, about
25% or about 30% by weight of the composition, or at least
0.01%, at least 0.05%, at least 0.075%, at least 0.1%,
at least 0.25%, at least 0.5%, at least 0.75%, at least 1.0%, at least 1.5%, at least 2.0%, at least
2.5%, at least 3.0%, at least 4.0%, at least 5.0%,
at least 6.0%, at least 7.0%, at least 7.5%, at least
8.0%, at least 9.0%, at least 10.0%, at least 11%,
at least 12%, at least 13%, at least 14%, at least
15%, at least 20%, at least 25% or at least 30% by weight of the composition, or at most 0.01%, at most 0.05%, at most 0.075%, at most 0.1%, in the maximum 0.25%, maximum
0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0%, maximum 2.5%, maximum 3.0%, maximum 4 , 0%,
maximum 5.0%, maximum 6.0%, maximum 7.5%, maximum
8.0%, maximum 9.0%, maximum 10.0%, maximum 11%, maximum 12%, maximum 13%, maximum 14%, maximum 15%, maximum 20%, maximum 25% or maximum 30% by weight of the composition or about 0.1% to about 0.5%, about 0.1%
about 0.75%, about 0.1% to about 1.0%, about
0.1% to about 1.5%, about 0.1% to about 2.0%, about 0.1% to about 2.5%, about 0.1% to about 3 , 0%, about 0.1% to about 3.5%, about 0.1% to about 4.0%, about 0.1% to about 4.5%, about 0, 1% to about 5.0%, about 0.2% to about 0.5%, about 0.2% to about 0.75%,
about 0.2% to about 1.0%, about 0.2% to about 1.5%,
about 0.2% to about 2.0%, about 0.2% to about 2.5%,
about 0.2% to about 3.0%, about 0.2% to about 3.5%,
about 0.2% to about 4.0%, about 0.2% to about 4.5%,
about 0.2% to about 5.0%, about 0.5% to about 1.0%,
about 0.5% to about 1.5%, about 0.5% to about 2.0%,
about 0.5% to about 2.5%, about 0.5% to about 3.0%,
about 0.5% to about 4.0%, about 0.5% to about 5.0%,
about 0.5% to about 6.0%, about 0.5% to about 7.0%,
about 0.5% to about 8.0%, about 0.5% to about 9.0%,
about 0.5% to about 10.0%, about 1.0% to about
2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0%, about 1 , 0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%, about 1.0% to about 8, 0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 1.0% to about 15.0%, about 1.0 % to about 20.0%, about
1.0% to about 25.0%, about 1.0% to about 30.0%, about 2.0% to about 2.5%, about 2.0% to about 3 , 0%, about 2.0% to about 4.0%, about 2.0% to about 5.0%, about 2.0% to about 6.0%, about 2, 0% to about 7.0%, about 2.0% to about 7.5%, about 2.0% to about 8.0%, about 2.0% to about 9.0 %, about 2.0% to about 10.0%,
about 2.0% to about 15.0%, about 2.0% to about
20.0%, about 2.0% to about 25.0%, about 2.0% to about 30.0%, about 5.0% to about 6.0%, about 5 , 0% to about 7.0%, about 5.0% to about 7.5%, about 5.0%
about 8.0%, about 5.0% to about 9.0%, about
5.0% to about 10.0%, about 5.0% to about 11.0%, about 5.0% to about 12.0%, about 5.0% to about 13 , 0%,
about 5.0% to about 14.0%, about 5.0% to about
15.0%, about 5.0% to about 20.0%, about 5.0% to about 25.0%, about 5.0% to about 30.0%, about 6 , 0% to about 7.0%, about 6.0% to about 7.5%, about 6.0%
about 8.0%, about 6.0% to about 9.0%, about
6.0% to about 10.0%, about 6.0% to about 11.0%, about 6.0% to about 12.0%, about 6.0% to about 13 , 0%,
about 6.0% to about 14.0%, about 6.0% to about
15.0%, about 6.0% to about 20.0%, about 6.0% to about 25.0%, about 6.0% to about 30.0%, about 7 , 0% to about 8.0%, about 7.0% to about 9.0%, about 7.0%
about 10.0%, about 7.0% to about 11.0%, about
7.0% to about 12.0%, about 7.0% to about 13.0%, about 7.0% to about 14.0%, about 7.0% to about 15 , 0%,
about 7.0% to about 20.0%, about 7.0% to about
25.0%, about 7.0% to about 30.0%, about 8.0% to about 9.0%, about 8.0% to about 10.0%, about 8 , 0% to about 11.0%, about 8.0% to about 12.0%, about 8.0% to about 13.0%, about 8.0% to about 14, 0%, about 8.0% to about 15.0%, about 8.0% to about 20.0%, about 8.0% to about 25.0%, about 8.0 % to about 30.0%, about 9.0% to about 10.0%, about 9.0% to about 11.0%, about 9.0% to about 12.0% , about 9.0% to about 13.0%, about 9.0% to about 14.0%, about 9.0% to about 15.0%, about 9.0% to about 20.0%, about 9.0% to about 25.0%, about 9.0% to about 30.0%, about 10.0% to about 11.0%, about from 10.0% to about 12.0%, about 10.0% to about 13.0%, about 10.0% to about 14.0%, about 10.0% to about 15.0%, about 10.0% to about 20.0%, about 10.0% to about 25.0%, about 10.0% to about 30.0%, about 15 , 0% to about 20.0%, about 15.0% to about 25.0%, about 15.0% to about d and 30.0%, about 20.0% to about 25.0%, about 20.0% to about 30.0% or about 20.0% to about 30.0% by weight of composition.
127. Kit according to any one of claims 117 to 125, characterized in that the one or more aldehydes and / or one or more dialdehydes are in an amount of about 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm,
525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm,
850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm or 1,000 ppm, or at least 100 ppm, at least 125 ppm
150 ppm, at least 175 ppm, at least 200 ppm, at least
225 ppm, at least 250 ppm, at least 275 ppm, at least
300 ppm, at least 325 ppm, at least 350 ppm, at least
375 ppm, at least 400 ppm, at least 425 ppm, at least
450 ppm, at least 475 ppm, at least 500 ppm, at least
525 ppm, at least 550 ppm, at least 575 ppm, at least
600 ppm, at least 625 ppm, at least 650 ppm, at least
675 ppm, at least 700 ppm, at least 725 ppm, at least
750 ppm, at least 775 ppm, at least 800 ppm, at least
825 ppm, at least 850 ppm, at least 875 ppm, at least
900 ppm, at least 925 ppm, at least 950 ppm, at least
975 ppm or at least 1,000 ppm or at most 100 ppm, at most 125 ppm, at most 150 ppm, at most 175 ppm, at most 200 ppm, at most 225 ppm, at most 250 ppm, at most 275 ppm, at most 300 ppm, maximum 325 ppm, maximum 350 ppm, maximum 375 ppm, maximum 400 ppm, maximum 425 ppm, maximum 450 ppm, maximum 475 ppm, maximum 500 ppm, maximum 525 ppm 550 ppm, maximum 575 ppm, maximum 600 ppm, maximum 625 ppm, maximum 650 ppm, maximum 675 ppm, maximum 700 ppm, maximum 725 ppm, maximum 750 ppm, maximum 775 ppm, maximum 800 ppm, maximum 825 ppm, maximum 850 ppm, maximum 875 ppm, maximum 900 ppm, maximum 925 ppm, maximum 950 ppm, maximum 975 ppm or maximum 1,000 ppm.
128. Kit according to any one of claims 117 to 125, characterized in that the one or more aldehydes and / or one or more dialdehydes are in an amount of about 100 ppm to about 200 ppm, about 100 ppm to about 300 ppm, about 100 ppm to about 400 ppm, about 100 ppm to about 500 ppm, about 100 ppm to about 600 ppm, about 100 ppm to about 700 ppm, about 100 ppm to about 800 ppm, about 100 ppm to about 900 ppm, about 100 ppm to about 1,000 ppm, about 200 ppm to about 300 ppm, about 200 ppm to about 400 ppm, about 200 ppm to about 500 ppm, about 200 ppm to about 600 ppm, about 200 ppm to about 700 ppm, about 200 ppm to about 800 ppm, about 200 ppm to about 900 ppm, about 200 ppm to about 1,000 ppm, about 300 ppm to about 400 ppm, about 300 ppm to about 500 ppm, about 300 ppm to about 600 ppm, about 300 ppm to about 700 ppm, about 300 ppm to about 800 ppm, about from 300 ppm to about 900 ppm, about 300 ppm to about 1,000 ppm, about 400 ppm to about 500 ppm, about 400 ppm to about 600 ppm, about 400 ppm to about 700 ppm, about 400 ppm to about 800 ppm, about 400 ppm to about 900 ppm, about 400 ppm to about 1,000 ppm,
about 500 ppm to about 600 ppm, about 500 ppm to about 700 ppm, about 500 ppm to about 800 ppm, about 500 ppm to about 900 ppm, about 500 ppm to about 1,000 ppm, about 600 ppm to about 700 ppm, about 600 ppm to about 800 ppm, about 600 ppm to about 900 ppm, about 600 ppm to about 1,000 ppm, about 700 ppm to about 800 ppm, about 700 ppm to about 900 ppm, about 700 ppm to about 1,000 ppm, about 800 ppm to about 900 ppm, about 800 ppm to about 1,000 ppm or about 900 ppm to about 1,000 ppm.
129. Kit according to any one of claims 109, 110 or 112 to 128, characterized in that the one or more alcohols are methanol, ethanol, propanol, isopropanol, butanol, pentanol and 1-hexadecanol.
130. Kit according to any one of claims 109, 110 or 112 to 129, characterized in that the one or more alcohols are in an amount of about 40%, about 45%, about 50%, about about 55%, about 60%, about 65%, about 70%, about 75%, about 80%, about 85%, about 90%, about 95%, about 96%, about 97%, about 98% or about 99% by weight of the composition, or at least 40%, at least 45%, at least 50%, at least 55%, at least 60%, at least 65%, at least at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or at least 99% by weight composition, or a maximum of 40%, a maximum of 45%, a maximum of 50%, a maximum of 55%, a maximum of 60%, a maximum of 65%, a maximum of 70%, a maximum of 75%, a maximum of 80%, maximum 85%, maximum 90%, maximum 95%, maximum 96%, maximum 97%, maximum 98% or maximum 99% by weight of the composition, about 40% to about 50%, about 40% a about 60%, about 40% to about 70%, about 40% to about 80%, about 40% to about 90%, about 40% to about 95%, about 40% to about 97%, about 40% to about 99%, about 50% to about 60%, about 50% to about 70%, about 50% to about 80%, about 50% to about 90%, about 50% to about 95%, about 50% to about 97%, about 50% to about 99%, about 60% to about 70%, about 60% to about 80%, about 60% to about 90%, about 60% to about 95%, about 60% to about 97%, about 60% to about 99%, about 70% to about 80%, about 70% to about 90%, about 70% to about 95%, about 70% to about 97%, about 70% to about 99%, about 80% to about 90%, about 80% to about 95%, about 80% to about 97%, about 80% to about 99%, about 90% to about 95%, about 90% to about 97%, about 90% to about 99% by weight of the composition.
131. Kit according to any one of claims 112 to 130, characterized in that the one or more cationic surfactants include one or more quaternary ammonium surfactants, pH-dependent primary amine surfactant, pH-dependent secondary amine surfactant , pH-dependent tertiary amine surfactant or any combination thereof.
132. Kit according to claim 131, characterized in that the one or more quaternary ammonium surfactants include benzalkonium chloride (BAC), benzethonium chloride (BZT), benzododecinium bromide (or dimethyldodecylbenzylammonium bromide), bronidox , (or 5-bromo-5-nitro-1,3-dioxane), carbetopendecinium bromide, ketalkonium chloride (CKC), cetrimony, cetrimide, cetylpyridinium chloride (CPC), cetyl trimethylammonium bromide (CTAB or cetrimonium bromide) ) and cetyl trimethylammonium chloride (CTAC or cetrimonium chloride), didecyldimethylammonium chloride (DDAC), dioctadecyldimethylammonium bromide (DODAB or dichloroethylammonium chloride) behenrimone), dofanium chloride, domiphene bromide, methylbenzetonium chloride, octenidine dihydrochloride, polyhydronium chloride, stearalkonium chloride (or dimethylbenzyloctadecyl) ammonium), tetraethylammonium bromide, tetramethylammonium hydroxide (TMAH) and tonzonium bromide, or any combination thereof.
133. Kit according to any of the claims
112 to 132, characterized by the fact that the one or more cationic surfactants are in a number of aspects, for example, about 0.001%, about 0.005%, about
0.0075%, about 0.01%, about 0.05%, about 0.075%,
about 0.1%, about 0.2%, about 0.3%, about 0.4%,
about 0.5%, about 0.6%, about 0.7%, about 0.8%,
about 0.9%, about 1.0%, about 1.5%, about 2.0%,
about 2.5%, about 3.0%, about 4.0%, about 5.0%,
about 6.0%, about 7.0%, about 7.5%, about 8.0%,
about 9.0% or about 10.0% by weight of the composition, or at least 0.001%, at least 0.005%, at least 0.0075%,
at least 0.01%, at least 0.05%, at least 0.075%, at least 0.1%, at least 0.25%, at least 0.5%, at least
0.75%, at least 1.0%, at least 1.5%, at least 2.0%,
at least 2.5%, at least 3.0%, at least 4.0%, at least
5.0%, at least 6.0%, at least 7.0%, at least 7.5%,
at least 8.0%, at least 9.0% or at least 10.0% by weight of the composition, or at most 0.001%, at most 0.005%, at most 0.0075%, at most 0.01%, at most 0.05% at most
0.075%, maximum 0.1%, maximum 0.25%, maximum 0.5%, maximum 0.75%, maximum 1.0%, maximum 1.5%, maximum 2.0 %,
maximum 2.5%, maximum 3.0%, maximum 4.0%, maximum
5.0%, at most 6.0%, at most 7.5%, at most 8.0%, at most 9.0% or at most 10.0% by weight of the composition or about 0.001% at about 0.005%, about 0.001% to about
0.0075%, about 0.001% to about 0.01%, about 0.001%
about 0.025%, about 0.001% to about 0.05%, about 0.001% to about 0.075%, about 0.001% to about 0.1%,
about 0.001% to about 0.25%, about 0.001% to about
0.75%, about 0.001% to about 1.0%, about 0.005% to about 0.0075%, about 0.005% to about 0.01%, about
0.005% to about 0.025%, about 0.005% to about 0.05%,
about 0.005% to about 0.075%, about 0.005% to about 0.1%, about 0.005% to about 0.25%, about 0.005%
about 0.75%, about 0.005% to about 1.0%, about
0.01% to about 0.05%, about 0.01% to about 0.075%,
about 0.01% to about 0.1%, about 0.01% to about
0.25%, about 0.01% to about 0.5%, about 0.01% to about 0.75%, about 0.01% to about 1.0%, about 0 , 01% to about 1.5%, about 0.01% to about 2.0%, about 0.01%
about 2.5%, about 0.05% to about 0.075%, about
0.05% to about 0.1%, about 0.05% to about 0.25%, about 0.05% to about 0.5%, about 0.05% to about 0 , 75%,
about 0.05% to about 1.0%, about 0.05% to about
1.5%, about 0.05% to about 2.0%, about 0.05% to about 2.5%, about 0.1% to about 0.5%, about 0 , 1% to about 0.75%, about 0.1% to about 1.0%, about 0.1% to about 1.5%, about 0.1% to about 2, 0%, about 0.1%
about 2.5%, about 0.1% to about 3.0%, about
0.1% to about 4.0%, about 0.1% to about 5.0%, about 0.2% to about 0.5%, about 0.2% to about 0 , 75%,
about 0.2% to about 1.0%, about 0.2% to about 1.5%,
about 0.2% to about 2.0%, about 0.2% to about 2.5%,
about 0.2% to about 3.0%, about 0.2% to about 4.0%,
about 0.2% to about 5.0%, about 0.5% to about 1.0%,
about 0.5% to about 1.5%, about 0.5% to about 2.0%,
about 0.5% to about 2.5%, about 0.5% to about 3.0%,
about 0.5% to about 4.0%, about 0.5% to about 5.0%,
about 0.5% to about 6.0%, about 0.5% to about 7.0%,
about 0.5% to about 8.0%, about 0.5% to about 9.0%,
about 0.5% to about 10.0%, about 1.0% to about
2.5%, about 1.0% to about 3.0%, about 1.0% to about 4.0%, about 1.0% to about 5.0%, about 1 , 0% to about 6.0%, about 1.0% to about 7.0%, about 1.0% to about 7.5%, about 1.0% to about 8, 0%, about 1.0% to about 9.0%, about 1.0% to about 10.0%, about 2.0% to about 2.5%, about 2.0 % to about 3.0%, about 2.0%
about 4.0%, about 2.0% to about 5.0%, about
2.0% to about 6.0%, about 2.0% to about 7.0%, about 2.0% to about 7.5%, about 2.0% to about 8 , 0%, about 2.0% to about 9.0%, about 2.0% to about 10.0%,
about 5.0% to about 6.0%, about 5.0% to about 7.0%,
about 5.0% to about 7.5%, about 5.0% to about 8.0%,
about 5.0% to about 9.0%, about 5.0% to about
10.0%, about 5.0% to about 11.0%, about 5.0% to about 12.0%, about 5.0% to about 13.0%, about 5 , 0% to about 14.0% or about 5.0% to about 15.0% by weight of the composition.
134. Method for cleaning, disinfecting and / or sterilizing a device, the method being characterized by the fact that it comprises, essentially consists of, or consists of applying a composition, as defined in any one of claims 1 to 108, or applying the components, as defined in any one of claims 109 to 133, to a device, the application of which cleans, disinfects and / or sterilizes the device.
135. Composition according to any one of claims 1 to 108, or components, as defined in any one of claims 109 to 133, characterized by the fact that they are intended for use in cleaning, disinfecting and / or sterilizing a device .
136. Use of a composition, as defined in any of claims 1 to 108, or use of components, as defined in any of claims 109 to 133, characterized by the fact that it is intended to clean, disinfect and / or sterilize a device.
137. Method for cleaning, disinfecting and / or sterilizing a surface area, the method being characterized by the fact that it comprises, essentially consists of, or consists of applying a composition, as defined in any one of claims 1 to 108, or applying the components, as defined in any of claims 109 to 133, to a device, the application of which cleans, disinfects and / or sterilizes the device.
138. Composition according to any one of claims 1 to 108, or components as defined in any one of claims 109 to 133, characterized by the fact that they are intended for use in cleaning, disinfecting and / or sterilizing an area of surface.
139. Use of a composition according to any one of claims 1 to 108, or use of components as defined in any one of claims 109 to 133, characterized by the fact that it is intended to clean, disinfect and / or sterilize a surface area.
140. Method according to claim 137, or use as defined in claim 138 and according to claim 139, characterized in that the surface area is a porous surface area or a non-porous surface area .
141. Method according to claim 137 or 140, or use, as defined in any of claims 138 to 140, characterized by the fact that the surface area comprises a table top, a bench, a floor, a wall, a ceiling, a window, a door, a handle, a shower, a bathtub, a sink, faucet, a toilet, a toilet seat, a drain, an equipment, a machinery, personal protective equipment, equipment personal risk, a medical device, a dental device, a pharmaceutical device, a veterinary device, a mortuary device or human skin.
142. Method, according to claim 141, or use, according to claim 141, characterized by the fact that the medical device is a surgical instrument, a respiratory therapy instrument, an anesthesia instrument, a catheter, a implant, probe, endoscope, arthroscope, laparoscope, blade, cystoscope, spirometer, CPAP mask and tube, dialysis instrument and accessories, cardiopulmonary machine and accessories, cardiopulmonary bypass machine and accessories and a diaphragm adjustment ring.
143. Method for cleaning, disinfecting and / or sterilizing a microbial infection in an individual, the method being characterized by the fact that it comprises, consists essentially of, or consists of applying a composition, as defined in any one of claims 1 to 108, or applying the components, as defined in any one of claims 109 to 133, to the individual, the application of which cleans, disinfects and / or sterilizes the device.
144. Composition according to any one of claims 1 to 108, or components, as defined in any one of claims 109 to 133, characterized by the fact that they are intended for use in cleaning, disinfecting and / or sterilizing an infection microbial in an individual.
145. Use of a composition, as defined in any of claims 1 to 108, or use of components, as defined in any of claims 109 to 133, characterized by the fact that it is intended to clean, disinfect and / or sterilize a microbial infection in an individual.
146. Method according to claim 143, or use as defined in claim 144 and according to claim 145, characterized in that the application of the composition is applied topically or administered enterally or parenterally.
147. Method according to any one of claims 137, 140, 141, 143 or 146, or use according to any one of claims 138 to 141 or 144 to 146, characterized in that the composition is applied daily , every other day, every three days, once a week, multiple times a week, once a month, multiple times a month, once a year or multiple times a year, as desired.
148. Method according to any one of claims 137, 140, 141, 143, 146 or 147, or the use according to any one of claims 138 to 141 or 144 to 147, characterized by the fact that the composition is applied multiple times a day.
149. Method according to any one of claims 134, 137 or 143, or use according to any one of claims 135, 136, 138, 139, 144 or 145, characterized in that the composition is applied to a device, such as a medical device, a surface or an individual, for example, for about 1 minute, about 5 minutes, about 10 minutes, about 15 minutes, about 20 minutes, about 25 minutes, about 30 minutes, about 35 minutes, about 40 minutes, about 45 minutes, about 50 minutes, about 55 minutes, about 60 minutes, about 70 minutes, about 80 minutes, about 90 minutes, about 100 minutes, about 110 minutes, or about 120 minutes; or is applied to a device, such as a medical device, a surface or an individual, for example, for at least 1 minute, at least 5 minutes, at least 10 minutes, at least 15 minutes, at least 20 minutes, at least 25 minutes, at least 30 minutes, at least 35 minutes, at least 40 minutes, at least 45 minutes, at least 55 minutes, at least 60 minutes, at least 70 minutes, at least 80 minutes, at least 90 minutes, at least 100 minutes, at least 110 minutes or at least 120 minutes.
In still other aspects of this modality, a composition disclosed in this document is applied to the device, such as a medical device, a surface or an individual, for example for a maximum of 1 minute, a maximum of 5 minutes, a maximum of 10 minutes, a maximum of 15 minutes, maximum 20 minutes, maximum 25 minutes, maximum 30 minutes, maximum 35 minutes, maximum 40 minutes, maximum 45 minutes, maximum 50 minutes, maximum 55 minutes, maximum 60 minutes, maximum 70 minutes, maximum 80 minutes, maximum 90 minutes, maximum 100 minutes, maximum 110 minutes or maximum 120 minutes; or is applied to a device, such as a medical device, a surface, or an individual, for example, for about 1 minute to about 5 minutes, about 1 minute to about 10 minutes, about 1 minute to about 15 minutes, about 1 minute to about 20 minutes, about 1 minute to about 25 minutes, about 1 minute to about 30 minutes, about 1 minute to about 35 minutes, about 1 minute to about 40 minutes, about 1 minute to about 45 minutes, about 1 minute to about 50 minutes, about 1 minute to about 55 minutes, about 1 minute to about 60 minutes, about 5 minutes to about 10 minutes, about 5 minutes to about 15 minutes,
about 5 minutes to about 20 minutes, about 5 minutes to about 25 minutes, about 5 minutes to about 30 minutes, about 5 minutes to about 35 minutes, about
5 minutes to about 40 minutes, about 5 minutes to about 45 minutes, about 5 minutes to about 50 minutes,
about 5 minutes to about 55 minutes, about 5 minutes to about 60 minutes, about 5 minutes to about 70 minutes, about 5 minutes to about 80 minutes, about
5 minutes to about 90 minutes, about 5 minutes to about 100 minutes, about 5 minutes to about 110 minutes,
about 5 minutes to about 120 minutes, about 10 minutes to about 15 minutes, about 10 minutes to about 20 minutes, about 10 minutes to about 25 minutes,
about 10 minutes to about 30 minutes, about 10 minutes to about 35 minutes, about 10 minutes to about 40 minutes, about 10 minutes to about 45 minutes,
about 10 minutes to about 50 minutes, about 10 minutes to about 55 minutes, about 10 minutes to about 60 minutes, about 10 minutes to about 70 minutes,
about 10 minutes to about 80 minutes, about 10 minutes to about 90 minutes, about 10 minutes to about 100 minutes, about 10 minutes to about 110 minutes,
about 10 minutes to about 120 minutes, about 15 minutes to about 20 minutes, about 15 minutes to about 25 minutes, about 15 minutes to about 30 minutes,
about 15 minutes to about 35 minutes, about 15 minutes to about 40 minutes, about 15 minutes to about 45 minutes, about 15 minutes to about 50 minutes,
about 15 minutes to about 55 minutes, about 15 minutes to about 60 minutes, about 15 minutes to about 70 minutes, about 15 minutes to about 80 minutes,
about 15 minutes to about 90 minutes, about 15 minutes to about 100 minutes, about 15 minutes to about 110 minutes, about 15 minutes to about 120 minutes,
about 20 minutes to about 25 minutes, about 20 minutes to about 30 minutes, about 20 minutes to about 35 minutes, about 20 minutes to about 40 minutes,
about 20 minutes to about 45 minutes, about 20 minutes to about 50 minutes, about 20 minutes to about 55 minutes, about 20 minutes to about 60 minutes,
about 20 minutes to about 70 minutes, about 20 minutes to about 80 minutes, about 20 minutes to about 90 minutes, about 20 minutes to about 100 minutes,
about 20 minutes to about 110 minutes, about 20 minutes to about 120 minutes, about 25 minutes to about 30 minutes, about 25 minutes to about 35 minutes,
about 25 minutes to about 40 minutes, about 25 minutes to about 45 minutes, about 25 minutes to about 50 minutes, about 25 minutes to about 55 minutes,
about 25 minutes to about 60 minutes, about 25 minutes to about 70 minutes, about 25 minutes to about 80 minutes, about 25 minutes to about 90 minutes,
about 25 minutes to about 100 minutes, about 25 minutes to about 110 minutes, about 25 minutes to about 120 minutes, about 30 minutes to about 35 minutes,
about 30 minutes to about 40 minutes, about 30 minutes to about 45 minutes, about 30 minutes to about 50 minutes, about 30 minutes to about 55 minutes,
about 30 minutes to about 60 minutes, about 30 minutes to about 70 minutes, about 30 minutes to about 80 minutes, about 30 minutes to about 90 minutes,
about 30 minutes to about 100 minutes, about 30 minutes to about 110 minutes, about 30 minutes to about 120 minutes, about 35 minutes to about 40 minutes,
about 35 minutes to about 45 minutes, about 35 minutes to about 50 minutes, about 35 minutes to about 55 minutes, about 35 minutes to about 60 minutes,
about 35 minutes to about 70 minutes, about 35 minutes to about 80 minutes, about 35 minutes to about 90 minutes, about 35 minutes to about 100 minutes,
about 35 minutes to about 110 minutes, about 35 minutes to about 120 minutes, about 40 minutes to about 45 minutes, about 40 minutes to about 50 minutes,
about 40 minutes to about 55 minutes, about 40 minutes to about 60 minutes, about 40 minutes to about 70 minutes, about 40 minutes to about 80 minutes,
about 40 minutes to about 90 minutes, about 40 minutes to about 100 minutes, about 40 minutes to about 110 minutes, about 40 minutes to about 120 minutes,
about 45 minutes to about 50 minutes, about 45 minutes to about 55 minutes, about 45 minutes to about 60 minutes, about 45 minutes to about 70 minutes,
about 45 minutes to about 80 minutes, about 45 minutes to about 90 minutes, about 45 minutes to about 100 minutes, about 45 minutes to about 110 minutes,
about 45 minutes to about 120 minutes, about 50 minutes to about 55 minutes, about 50 minutes to about 60 minutes, about 50 minutes to about 70 minutes,
about 50 minutes to about 80 minutes, about 50 minutes to about 90 minutes, about 50 minutes to about 100 minutes, about 50 minutes to about 110 minutes,
about 50 minutes to about 120 minutes, about 55 minutes to about 60 minutes, about 55 minutes to about 70 minutes, about 55 minutes to about 80 minutes,
about 55 minutes to about 90 minutes, about 55 minutes to about 100 minutes, about 55 minutes to about 110 minutes, about 55 minutes to about 120 minutes,
about 60 minutes to about 70 minutes, about 60 minutes to about 80 minutes, about 60 minutes to about 90 minutes, about 60 minutes to about 100 minutes,
about 60 minutes to about 110 minutes, about 60 minutes to about 120 minutes, about 70 minutes to about 80 minutes, about 70 minutes to about 90 minutes,
about 70 minutes to about 100 minutes, about 70 minutes to about 110 minutes, about 70 minutes to about 120 minutes, about 80 minutes to about 90 minutes,
about 80 minutes to about 100 minutes, about 80 minutes to about 110 minutes, about 80 minutes to about 120 minutes, about 90 minutes to about 100 minutes,
about 90 minutes to about 110 minutes, about 90 minutes to about 120 minutes, about 100 minutes to about 110 minutes, about 100 minutes to about 120 minutes, or about 110 minutes to about 120 minutes.

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同族专利:

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公开号 | 公开日

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EP3645017A4|2021-05-19|

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JP2020526577A|2020-08-31|

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US20200375188A1|2020-12-03|

---

WO2019006217A1|2019-01-03|

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EP3645017A1|2020-05-06|

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US10412968B2|2019-09-17|

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US20190364901A1|2019-12-05|

---

AU2018294246A1|2020-02-13|

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ZA202000532B|2021-04-28|

---

US20200375189A1|2020-12-03|

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KR20200034722A|2020-03-31|

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US10750747B2|2020-08-25|

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US10750748B2|2020-08-25|

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CA3067855A1|2019-01-03|

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IL271623D0|2020-02-27|

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SG11201912534SA|2020-01-30|

---

US20190364900A1|2019-12-05|

---

US20190000086A1|2019-01-03|

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CN111032060A|2020-04-17|

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法律状态:
2021-11-03| B350| Update of information on the portal [chapter 15.35 patent gazette]|

优先权:

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申请号 | 申请日 | 专利标题

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US201762526175P| true| 2017-06-28|2017-06-28|

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US62/526,175|2017-06-28|

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US201762577225P| true| 2017-10-26|2017-10-26|

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US62/577,225|2017-10-26|

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PCT/US2018/040155|WO2019006217A1|2017-06-28|2018-06-28|Compositions, methods and uses for cleaning, disinfecting and/or sterilizing|

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